Central Nervous System

News Central Nervous System

• EPA awards UH lead role to study toxin effects on embryonic development

  Most people would agree that arsenic, lead, mercury, benzene and carbon monoxide pose dangers to humans. Not many, though, realize that the average person is exposed to about 10,000 different chemicals per day. Thanks to a $3.2 million grant from the Environmental Protection Agency (EPA) and its Sc more

• The popular insect repellent deet is neurotoxic

  The active ingredient in many insect repellents, deet, has been found to be toxic to the central nervous system. Researchers writing in BMC Biology say that more investigations are urgently needed to confirm or dismiss any potential neurotoxicity to humans, especially when deet-based repellents are more

• Authorized generics agreements – last ditch effort on part of branded pharma

  As pay-for-delay agreements look to be on the way out of the pharmaceutical industry in Europe and the US, a new report by independent market analyst Datamonitor forecasts that the number of authorized generics (AG) agreements will grow, in tandem with the increasing convergence between branded and more

Publications Central Nervous System

• Structure-Based Approaches to Ligands for G-Protein-Coupled Adenosine and P2Y Receptors, from Small Molecules to Nanoconjugates†

  Adenosine receptor (ARs) and P2Y receptors (P2YRs) that respond to extracellular nucleosides/nucleotides are associated with new directions for therapeutics. The X-ray structures of the A2AAR complexes with agonists and antagonists are examined in relationship to the G-protein-coupled receptor (GPCR more

• IJMS, Vol. 14, Pages 9820-9833: Anti-Inflammatory Effect of Ginsenoside Rg5 in Lipopolysaccharide-Stimulated BV2 Microglial Cells

  Microglia are resident immune cells in the central nervous system. They play a role in normal brain development and neuronal recovery. However, overactivation of microglia causes neuronal death, which is associated with neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease. more

• NMR Structure of Calmodulin Complexed to an N-Terminally Acetylated α-Synuclein Peptide

  Calmodulin (CaM) is a calcium binding protein that plays numerous roles in Ca-dependent cellular processes, including uptake and release of neurotransmitters in neurons. α-Synuclein (α-syn), one of the most abundant proteins in central nervous system neurons, helps maintain presynaptic vesicles cont more

Market studies Central Nervous System

• Zeltia, S.A. (ZEL) - Financial and Strategic SWOT Analysis Review

  Zeltia, S.A. has been engaged in the management, support, and promotion of its investees in the chemical-pharmaceutical sector. It also involves in the acquisition and refurbishment of real estate for lease. Through its subsidiaries, the company engages in the research, development, production, and more

• China GABA (Gamma-aminobutyric Acid) Market Report, 2007-2008

  γ－aminobutyric acid is also called 4- aminobutyric acid, piperidine acid and GABA (Gamma-aminobutyric acid). It is a natural amino acid without protein. GABA is an important inhibitory neurotransmitter in the mammalian central nervous system, with the functions of nerves calming, cerebral blood circ more

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