Drug Delivery

Companies Drug Delivery

Wyatt Technology Europe GmbH, Germany

Light scattering for the masses! The world's leading manufacturer of DAWN and miniDAWN multi-angle light scattering (MALS) instruments for determining the absolute molar masses and sizes of polymers and biopolymers in solution. These detectors, and Wyatt's ASTRA V GPC software, interface with any s more

News Drug Delivery

• Edible electronics

  Scientists in the US have designed an ingestible electronic device that is composed entirely of edible materials and produces its own electric current. The ingestible current source consists of flexible polymer electrodes and a sodium ion electrochemical cell. Having flexible polymer electrodes mean more

• Origami meets chemistry in scholarly video-article
  

  The nanotechnology research space is rapidly growing, with vast implications for the healthcare, consumer electronics, surveillance, and defense industries. However, a major limitation to this research is the ability to create particles that vary in shape and function on a micrometer or nanometer sc more

• Ionic liquids could aid in the delivery of active pharmaceutical compounds in the body

  US scientists have provided a strategy to improve the properties of active pharmaceutical ingredients (APIs) by combining ionic liquids (used to improve the properties of solid APIs) with prodrugs (used to improve solubility, permeability and bioavailability of APIs). The prodrug ionic liquids prese more

White papers Drug Delivery

• Structural and Chemical 3D Imaging with AFM and Raman.
  

  In the Life Sciences and Bio-medical Research, the characterization of chemical compounds within cells or tissues is one of the most important and difficult tasks for researchers to perform. The development of pharmaceuticals such as drug delivery coatings or capsules also requires as much information as possible about their chemical and structural compositions. For the fields of nanotechnology and materials science, a thorough knowledge of the samples' surface morphology on a sub-micron scale is essential more

• Automated Dynamic Light Scattering
  

  DLS analysis is a widely applied, non-invasive method for measuring the effective size of molecules in solution. This technique yields valuable information for the characterization of molecules and particles. It facilitates formerly laborious and time consuming measurements, e.g. screening for aggregates or determining optimal crystallization conditions for proteins. The Wyatt Plate Reader is the instrument of choice for any application where molecular size, stability and aggregation are of interest. It reads industry standard microplates with up to 1536 samples automatically and temperature-controlled, if desired. The applications of the technique are wide ranging and include many of the fastest growing areas of research - proteins, biomaterials, liposomes and micelles as well as the established uses for particle sizing and aggregation detection. Conscious of the numerous characterization challenges in the area of drug delivery systems and therapeutic antibodies more

Publications Drug Delivery

• Gelation of Ethosome-like Catanionic Vesicles by Water-Soluble Polymers: Ethanol and Cholesterol Effects

  Ethosome-like catanionic vesicles are vesicular carriers prepared by using ion-pair amphiphiles (IPAs) and relatively high concentrations of ethanol through a semispontaneous process for dermal drug delivery. In this work, the effects of ethanol and cholesterol on the polymer configuration and vesic more

• Tumor Endothelial Cell-Specific Drug Delivery System Using Apelin-Conjugated Liposomes

  by Hiroki Kawahara, Hisamichi Naito, Kazuhiro Takara, Taku Wakabayashi, Hiroyasu Kidoya, Nobuyuki Takakura Background A drug delivery system specifically targeting endothelial cells (ECs) in tumors is required to prevent normal blood vessels from being damaged by angiogenesis inhibitors. The purp more

• Materials, Vol. 6, Pages 2410-2435: Bio-based Films from Linter Cellulose and Its Acetates: Formation and Properties

  This paper describes the results obtained on the preparation of films composed of linter cellulose and the corresponding acetates. The acetylation was carried out in the LiCl/DMAc solvent system. Films were prepared from a LiCl/DMAc solution of cellulose acetates (degree of substitution, DS 0.8–2.9) more

Websites Drug Delivery