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Aniracetam (Draganon®, Sarpul®, Ampamet®) is a nootropic drug of the racetam family purported to be considerably more potent than piracetam. It is lipid soluble and has possible cognition enhancing effects. It has been tested in animals extensively, Alzheimer's patients and temporarily-impaired healthy subjects, but has not been tested in healthy, unimpaired humans. It has shown potential as an anxiolytic in three clinical animal models.
After a confirmed test of the anxiolytic efficacy in a mouse model, receptor antagonists haloperidol, mecamylamine, and ketanserin were applied. Haloperidol completely reversed the anxiolytic effects, and mecamylamine and ketanserin nearly completely reversed the effects. This shows that aniracetam's anxiolytic mechanism is facilitated by D2/D3 dopamine, nicotinic acetylcholine, and 5-HT2A receptors.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Aniracetam". A list of authors is available in Wikipedia.|