An antidiarrhoeal drug is any medication which provides symptomatic relief for diarrhoea.
- Electrolyte solutions are used to replace lost fluids and salts in acute cases.
- Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, ispaghul, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
- Absorbents absorb toxic substances that cause infective diarrhoea, methylcellulose is an absorbent as well.
- Opiates slow intestinal transit, but Loperamide is most commonly used, since it doesn't have the usual narcotic side effects.
|Antidiarrheals, intestinal anti-inflammatory/anti-infective agents (A07)|
|Intestinal anti-infectives||Antibiotics (Neomycin, Nystatin, Natamycin, Streptomycin, Polymyxin B, Paromomycin, Amphotericin B, Kanamycin, Vancomycin, Colistin, Rifaximin)
Sulfonamides (Phthalylsulfathiazole, Sulfaguanidine, Succinylsulfathiazole)
other (Miconazole, Broxyquinoline, Acetarsol, Nifuroxazide, Nifurzide)
|Intestinal adsorbents||Charcoal - Bismuth - Pectin - Kaolin - Crospovidone - Attapulgite - Diosmectite|
|Antipropulsives||Diphenoxylate - Opium - Loperamide - Difenoxin|
|Intestinal anti-inflammatory agents||corticosteroids acting locally (Prednisolone, Hydrocortisone, Prednisone, Betamethasone, Tixocortol, Budesonide, Beclometasone)
antiallergic agents, excluding corticosteroids (Cromoglicic acid)
aminosalicylic acid and similar agents (Sulfasalazine, Mesalazine, Olsalazine, Balsalazide)
|Antidiarrheal micro-organisms||Saccharomyces boulardii|
|Other antidiarrheals||Albumin tannate - Ceratonia - Racecadotril|