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Auraptene

Auraptene

IUPAC name	7-((E)-3, 7-Dimethylocta-2, 6-dienyloxy)-2H-chromen-2-one
Other names	Aurapten 7-Geranyloxycoumarin
Identifiers
CAS number	495-02-3
PubChem	1550607
SMILES	CC(=CCC/C(=C/COC1=CC2=C(C=C1)C=CC(=O)O2)/C)C
Properties
Molecular formula	C₁₉H₂₂O₃
Molar mass	298.38 g mol^-1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Auraptene is a natural bioactive monoterpene coumarin ether. It was first isolated from members of the genus Citrus. Auraptene has shown a remarkable effect in the prevention of degenerative diseases. Many studies have reported the effect of auraptene as a chemopreventative agent against cancers of liver, skin, tongue, esophagus, and colon in rodent models.^[1] The effect in humans is not yet known.

References

^ Curini, M., Carvotto, G., Epifano, F. and Giannone, G. "Chemistry and Biological Activity of Natural and Synthetic Prenyloxycoumarins"(2006). Current Medicinal Chemistry, 13, 199-222.

Categories: Terpenes and terpenoids | Phenylpropanoids | Ethers