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CP 55,940


CP 55,940
Systematic (IUPAC) name
2-[(1S,2R,5S)-5-hydroxy-2-(3-hydroxypropyl) cyclohexyl]-5-(2-methyloctan-2-yl)phenol
Identifiers
CAS number	83002-04-4
ATC code	?
PubChem	3086156
Chemical data
Formula	C₂₄H₄₀O₃
Mol. mass	376.573 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

CP 55,940, is a cannabinoid which mimics the effects of naturally occurring THC (the psychoactive compound found in marijuana). CP 55,940 was created by Pfizer in 1974 and was never marketed because of its highly psychoactive nature. It is currently used by scientists to study cannabinoid effects in biology. Some effects that have been noted are a greatly decreased rates of lever pressing in exposed mice, and a greater reaction to opiates in exposed mice. CP-55940 is 45 times more potent than Δ⁹-THC, and fully antagonized by rimonabant (SR141716A) (Life Sci 1996;58:1239-47; last update 010106). CP 55940 produces cannabis-like effects in humans at a dose of 0.25 - 1 milligram and could potentially be used as an alternative to medicinal marijuana which would be illegal (schedule one) under analogue laws rather than by specific mention.

Additional recommended knowledge

v • d • e Cannabinoids
Plant cannabinoids	CBD • CBDV • CBN • CBG • CBV • CBL • THC • THC-C4 • 11-Hydroxy-THC • THCV
Synthetic cannabinoids	Ajulemic acid • AM251 • CP 55,940 • DMHP • Dronabinol • HU-210 • JWH-133 • Levonantradol • Methanandamide • Nabilone • Nabitan • Parahexyl • Pravadoline • Rimonabant • THC-O-acetate • THC-O-phosphate • WIN 55,212-2
Endogenous cannabinoids	Arachidonoyl ethanolamide (Anandamide or AEA) • 2-Arachidonoylglycerol (2-AG) • 2-Arachidonyl glyceryl ether (noladin ether) • Virodhamine • N-arachidonoyl-dopamine (NADA)