Cytoprotectant

A cytoprotectant is any medication that combats ulcers not by reducing gastric acid but by increasing mucosal protection.

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Drugs that work in this manner include carbenoxolone, deglycyrrhizinised liquorice, sucralfate (aluminium hydroxide and sulphated sucrose), misoprostil (a prostaglandin analogue) and bismuth chelate (tri-potassium di-citrato bismuthate). Pregnant women should avoid as they can cause miscarriages. Misoprostil is used in South Africa as an abortifacent, despite not being registered for this use.