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In medicine, dinoprostone, is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour and also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts.
It is sold under the trade name of Cervidil (by Forest Laboratories, Inc.), Prostin E2 (by Pfizer Inc.) and Propess (by Ferring Pharmaceuticals), as a vaginal suppository, to prepare the cervix for labour; it is used to induce labour.
The chemical name is (5Z,11(alpha),13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid.
Like other prostaglandins, dinoprostone can be used as an abortifacient.
It works by binding and activating the prostaglandin E2 receptor.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Dinoprostone". A list of authors is available in Wikipedia.|