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EHNA


EHNA
Systematic (IUPAC) name
3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride
Identifiers
CAS number	59262-86-1
ATC code	?
PubChem	359137
Chemical data
Formula	C₁₄H₂₄Cl N₅O
Mol. mass	313.826 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type-2 (PDE2).^[1]^[2]

References

^ Podzuweit T, Nennstiel P and Muller A (1995) "Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine". Cell Signal 7:733-8. PMID 8519602
^ Méry PF, Pavoine C, Pecker F and Fischmeister R (1995). "Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes". Mol Pharmacol 48:121-130 PMID 7623766

v • d • e Selective Phosphodiesterase inhibitors (C01CE, G04BE)
PDE1	Vinpocetine
PDE2	EHNA
PDE3	Amrinone, Bucladesine, Enoximone, Milrinone
PDE4	HT-0712, Ibudilast, Mesembrine, Rolipram
PDE5	Avanafil, Sildenafil, Tadalafil, Udenafil, Vardenafil

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "EHNA". A list of authors is available in Wikipedia.

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