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Interleukin 20



Interleukin 20
Identifiers
Symbol IL20
Alt. Symbols , ZCYTO10, IL10D
Entrez 50604
HUGO 6002
OMIM 605619
RefSeq NM_018724
UniProt Q9NYY1
Other data
Locus Chr. 1 q32

Interleukin-20 (IL-20) is a protein belonging to the IL-10 family of cytokines. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells.[1]

References

  1. ^ Rich, B.E. Kupper, T.S., Interleukin 20. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2006, Volume 5, Number 3, pages 243-250.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Interleukin_20". A list of authors is available in Wikipedia.
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