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Interleukin 29

Interleukin 29
Identifiers
Symbol	IL29
Alt. Symbols	, IFNL1
Entrez	282618
HUGO	18363
OMIM	607403
RefSeq	NM_172140
UniProt	Q8IU54
Other data
Locus	Chr. 19 q13.13

Interleukin-29 (IL-29) is a protein of the helical cytokine family and is a type III interferon.^[1] It is also known as IFNλ1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon.

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IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses.

The IL-29 gene is found on chromosome 19 in humans.^[2]

References

^ Vilcek, Novel interferons. Nature Immunology, 2003, Volume 4, pages 8-9
^ P. Sheppard, et al., IL-28, IL-29 and their class II cytokine receptor IL-28R. Nature Immunology, 2003, Volume 4, pages 63-68.

v • d • e Cytokines: interleukins
IL-1 superfamily	IL-1 (IL-1Ra) - IL-18 - IL-33
IL-6 like/gp130 utilizing	IL-6 - IL-11 - IL-27 - IL-30 - IL-31
IL-10 family	IL-10 - IL-19 - IL-20 - IL-22 - IL-24 - IL-26
Interferon type III	IL-28 - IL-29
Common γ-chain family	IL-2/IL-15 - IL-3 - IL-4 - IL-7 - IL-9 - IL-13 - IL-21
IL-12 family	IL-12 - IL-23 - IL-27 - IL-35
Other	IL-5 - IL-8 - IL-14 - IL-16 - IL-17/IL-25 - IL-32

v • d • e Cytokines: interferons
Interferon type I	Interferon beta-1a - Interferon beta-1b - Pegylated interferon alfa-2a - Pegylated interferon alfa-2b
Interferon type II	Interferon-gamma
Interferon type III	Interleukin 28 - Interleukin 29