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Isopropamide


Isopropamide
Systematic (IUPAC) name
[4-amino-4-oxo-3,3-di(phenyl)butyl]-methyl-di(propan-2-yl)azanium
Identifiers
CAS number	71-81-8
ATC code	?
PubChem	3775
Chemical data
Formula	C₂₃H₃₃N₂O_{1 ⁺}
Mol. mass	353.52092 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	?(US)
Routes	Oral

Isopropamide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility. Chemically, it contains a quaternary ammonium group. It was discovered at Janssen Pharmaceutica in 1954.

References

Seeherman R, Isopropamide iodide: a long-acting anticholinergic, Del Med J. 1957 Oct;29(10):265-9.
Boss EG Jr, Buchanan GC, Effect of isopropamide iodide on basal gastric secretion in the human, Gastroenterology. 1957 Nov;33(5):730-6.

Category: Drugs