To use all functions of this page, please activate cookies in your browser.
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Lefetamine was invented in the 1940s and was widely abused in Japan  during the 1950s.  It has been researched for medicinal use but showed little advantage over other analgesics, although it did seem promising for treating opiate withdrawal it was not as good as buprenorphine for this purpose.  More recently it has been abused in Europe, but it remains an obscure drug on the illicit market.
Due to its chemical structure, it binds to opioid receptors while simultaneously inhibiting reuptake of dopamine and norepinephrine. Lefetamine has the necessary tertiary amine functional group required for opioid receptor recognition, as well as a phenethylamine skeleton (which is responsible for its amphetamine-like effects).  It is also reported to have some NMDA antagonist effects and to have neurotoxic properties. 
Boiling Point: 142-147° C
Optical Rotation: [α]D20 -124.2° (ethanol).
CAS number of hydrochloride: 14148-99-3
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Lefetamine". A list of authors is available in Wikipedia.|