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This article is about a pharmaceutical drug, for the automobile brand abbreviated as MBZ, see Mercedes-Benz

Systematic (IUPAC) name
methyl [(5-benzoyl-3H-benzoimidazol-2-yl)amino]formate
CAS number 31431-39-7
ATC code P02CA01
PubChem 7847434
DrugBank APRD01086
Chemical data
Formula C16H13N3O3 
Mol. mass 295.293 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 2.5 to 5.5 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status


Routes Oral

Mebendazole or MBZ, marketed as Ovex, Vermox, Antiox or Pripsen, is a benzimidazole drug that is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms. The active ingredient in Pripsen powder is piperazine.


Mebendazole (C16H13N3O3) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell. It is a spindle poison that induces chromosome nondisjunction.


Oral dosage is 100 mg 12 hourly for 3 days, although sometimes the dosage is just one 500 mg dose, followed by another dose two weeks later if the infection has not cleared up. The dosage may differ depending on which type of worm someone is infected with.

See also

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mebendazole". A list of authors is available in Wikipedia.
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