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Nateglinide belongs to the meglitinide class of blood glucose-lowering drugs.
Nateglinide lowers blood glucose by stimulating the release of insulin from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the β cells. This depolarizes the β cells and causes voltage-gated calcium channels to open. The resulting calcium influx induces fusion of insulin-containing vesicles with the cell membrane, and insulin secretion occurs.
Nateglinide is delivered in 60mg & 120mg tablet form.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nateglinide". A list of authors is available in Wikipedia.|