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Telmisartan (INN) (pronounced /tɛlmɪˈsɑrtən/) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. It is marketed under the trade names Micardis (Boehringer Ingelheim) and Pritor or Kinzal (Bayer Schering Pharma).
Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure.
New studies suggest that telmisartan may also have PPARγ agonistic properties that could potentially confer beneficial metabolic effects. This observation is currently being explored in clinical trials. In India it is available in the name of Telma by Glenmark Pharma according to www.sureshjain.com.
In India RANBAXY also markets it under the name of 'Teleact 20 mg"
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Telmisartan". A list of authors is available in Wikipedia.|