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Several reviews have been published.
The most probable mechanism involves the elimination of an alkyl anion as the final step:
The mechanism first involves the formation of the hydrazone in a mechanism that is probably analogous to the formation of an imine. Successive deprotonations eventually result in the evolution of nitrogen. The mechanism can be justified by the evolution of nitrogen as the thermodynamic driving force.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Wolff-Kishner_reduction". A list of authors is available in Wikipedia.|