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• Predicting the fate of underground carbon

  A team of researchers at the Massachusetts Institute of Technology has developed a new modeling methodology for determining the capacity and assessing the risks of leakage of potential underground carbon-dioxide reservoirs. One strategy for mitigating greenhouse gases is to inject compressed carbon more

• DSM and LibraGen sign agreement to co-develop transaminases for production of chiral amines

  DSM and LibraGen announced that they have signed an agreement to co-develop new omega-transaminases for production of chiral amines. Under the terms of the partnership, LibraGen will use its proprietary enzyme discovery and development to identify new enzymes for efficient conversion of a large spec more

• Study Finds New Properties in Non-Magnetic Materials

  A team of Penn State researchers has shown for the first time that the entire class of non-magnetic materials, such as those used in some computer components, could have considerably more uses than scientists had thought. The findings are important because they reveal previously unknown information more

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• Characterizing Biotherapeutics with HPLC
  

  As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

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• Leader Laboratory Mammalian Antibody Production (m/f)
  

  As one of the leading public biotech companies in Europe, we are committed to developing the medicines of the future. Building on our portfolio of innovative antibody technologies, we are actively pursuing new therapeutic approaches in close collaboration with the world‘s foremost pharmaceutical com more

Publications Expression

• Hepcidin, show some self-control! How the hormone of iron metabolism regulates its own expression

  Does the hormone of iron metabolism, hepcidin, exhibit 'self-control'? Hepcidin is a small, disulfide-rich peptide synthesized by the liver, which plays a keystone role in regulating systemic iron metabolism in mammals. Hepcidin acts by binding and triggering the lysosomal degradation of the cellul more

• Cooperative spin-crossover-like transitions in the inhomogeneous chain of exchange clusters

  A statistical theory of temperature-induced spin-crossover-like transitions has been developed for spin chains with a few exchange clusters in a unit cell. Using static magnetic susceptibility measurements, a general expression for the effective magnetic moment μeff of exchange clusters is obtained more

• Activated EGFR stimulates MUC1 expression in human uterine and pancreatic cancer cell lines

  Abstract MUC1 is a large cell surface mucin glycoprotein that plays diverse roles in both normal and tumor cell biology. These roles include mucosal hydration and protection, inhibition of embryo implantation, protection of tumor cells from the immune system and reduction of cytotoxic drug upta more

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