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• Manchester University scoops top prize at IChemE awards

  A carbon calculator software tool developed by chemical engineers at Manchester University clinched the top prize last night at the IChemE 2010 innovation and excellence awards. The CCalc helps companies to measure and reduce their carbon footprint at minimum cost and has been developed in collabora more

• APPLES consortium to develop improved in-line liquid monitoring technologies for the manufacture of high-value products

  A consortium of GlaxoSmithKline (GSK), Green Biologics and the Centre for Processing Innovation (CPI), led by Stratophase, is developing a cost-effective, multi-parametric sensor system for increasing the efficiency of high-value liquid based production processes. The £1.2m APPLES (Advanced Process more

• Food, fuels and face creams on chemical engineering group’s agenda

  IChemE’s new Formulated Product Engineering Subject Group staged its launch event in Birmingham, UK with more than 60 experts in attendance to share their formulation and product design knowledge. Novel approaches to formulation: from concept to product was staged in conjunction with the Royal Soci more

Publications GSK

• Prediction of Structure of Human WNT-CRD (FZD) Complex for Computational Drug Repurposing

  by Qurrat U. Ain, Umair Seemab, Sajid Rashid, Muhammad Sulaman Nawaz, Mohammad A. Kamal The observed genetic alterations of various extracellular and intracellular WNT (Wingless, Int-1 proto-oncogene) signaling components can result in an increase or decrease in gene expression, and hence more

• 3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles Are Selective Inhibitors of Plasmodium falciparum Glycogen Synthase Kinase-3

  Plasmodium falciparum is the infective agent responsible for malaria tropica. The glycogen synthase kinase-3 of the parasite (PfGSK-3) was suggested as a potential biological target for novel antimalarial drugs. Starting from hit structures identified in a high-throughput screening campaign, 3,6-dia more

• The Mitochondria-Targeted Antioxidants and Remote Kidney Preconditioning Ameliorate Brain Damage through Kidney-to-Brain Cross-Talk

  by Denis N. Silachev, Nikolay K. Isaev, Irina B. Pevzner, Ljubava D. Zorova, Elena V. Stelmashook, Svetlana V. Novikova, Egor Y. Plotnikov, Vladimir P. Skulachev, Dmitry B. Zorov Background Many ischemia-induced neurological pathologies including stroke are associated with high oxidative stress. more

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