Human Genome

News Human Genome

• American Chemical Society launches Prized Science video series

  Did life on Mars become life on Earth? What technology worked invisibly behind the headlines to make the Human Genome Project possible? How did wisps of material barely 1/50,000th the width of a human hair become forerunners of a new genre of medicines? Those topics highlight the premier episode of more

• NIH collaborates with EPA to improve the safety testing of chemicals

  Testing the safety of chemicals ranging from pesticides to household cleaners will benefit from new technologies and a plan for collaboration, according to federal scientists from the National Institutes of Health (NIH) and the U.S. Environmental Protection Agency (EPA), who announced a new toxicity more

• Richard F. Begley Named Vice President and General Manager of PerkinElmer Analytical Sciences

  PerkinElmer, Inc. announced that Richard F. Begley, Ph.D., has joined the Company as vice president and general manager of its Analytical Sciences business. In this position, he will develop and lead the growth strategy globally for the organization's entire portfolio of analytical instrumentation w more

Publications Human Genome

• Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity

  Ubiquitination is countered by a group of enzymes collectively called deubiquitinases (DUBs); ∼100 of them can be found in the human genome. One of the most interesting aspects of these enzymes is the ability of some members to selectively recognize specific linkage types between ubiquitin in polyub more

• The Impact of Computer Science in Molecular Medicine: Enabling High- Throughput Research

  Abstract: The Human Genome Project and the explosion of high-throughput data have transformed the areas of molecular and personalized medicine, which are producing a wide range of studies and experimental results and providing new insights for developing medical applications. Research in many more

• 2-Bromopalmitate Analogues as Activity-Based Probes To Explore Palmitoyl Acyltransferases

  Reversible S-palmitoylation is an important post-translational modification that regulates the trafficking, localization, and activity of proteins. Cysteine-rich Asp-His-His-Cys (DHHC) domain-containing enzymes are evolutionarily conserved protein palmitoyl acyltransferases (PATs). The human genome more

Websites Human Genome