Kinase Inhibitors

Companies Kinase Inhibitors

dichrom GmbH, Germany

dichrom - formerly SeQuant GmbH – is concentrating on the distribution and support of high quality products for liquid chromatography synthesis and isolation. The personal and individual customer support is of substantial importance for dichrom. Here a competent and comprehensive product and applica more

Biaffin GmbH & Co KG, Germany

Biaffin provides high quality services primarily specialising in biomolecular interaction analysis (BIA) using modern biosensors (Biacore). The application of biosensors based on surface plasmon resonance (SPR) allows monitoring of molecular interactions in real-time. Fast and accurate detection of more

News Kinase Inhibitors

• Altachem signs collaborative agreement with Korean research institute

  Altachem Pharma Ltd. has signed a Memorandum of Understanding ("MOU") with the Research Centre for Bioactive Materials (RCBM) at Korea's Chonbuk National University. The MOU is a formal agreement by the two organizations to identify collaborative research programs and is expected to quickly lead to more

• Bayer plans stock market flotation for chemicals activities and strategic refocus of health care business

  Following its successful reorganization, the Bayer Group intends to maintain its focus on its core businesses and in the future concentrate on health care, nutrition and innovative materials. For this reason, Bayer Chemicals (excluding H.C. Starck and Wolff Walsrode) is to be combined with certain p more

• Aventis: Prepared for the post-genome challenge

  Drug discovery in the post-genome era will be more complex than ever before, and only a network-centric approach to drug discovery will meet the new complexity challenge, Aventis executives told science writers at a press briefing on Tuesday on occasion of the Drug Technology Conference in Boston. more

Publications Kinase Inhibitors

• Activated EGFR stimulates MUC1 expression in human uterine and pancreatic cancer cell lines

  Abstract MUC1 is a large cell surface mucin glycoprotein that plays diverse roles in both normal and tumor cell biology. These roles include mucosal hydration and protection, inhibition of embryo implantation, protection of tumor cells from the immune system and reduction of cytotoxic drug upta more

• Insight into the structural requirements of benzimidazole derivatives as interleukin‐2 inducible t‐cell kinase inhibitors by computational explorations

  In the present work, a set of ligand‐ and receptor‐based 3D‐QSAR models were developed to explore the structure–activity relationship of 109 benzimidazole‐based interleukin‐2‐inducible T‐cell kinase (ITK) inhibitors. In order to reveal the requisite 3D structural features impacting the biological more

• Hypoxia Stimulates the EMT of Gastric Cancer Cells through Autocrine TGFβ Signaling

  by Junko Matsuoka, Masakazu Yashiro, Yosuke Doi, Yuhiko Fuyuhiro, Yukihiro Kato, Osamu Shinto, Satoru Noda, Shinichiro Kashiwagi, Naoki Aomatsu, Toshiki Hirakawa, Tsuyoshi Hasegawa, Kiyoshi Shimizu, Toshiyuki Shimizu, Atsushi Miwa, Nobuya Yamada, Tetsuji Sawada, Kosei Hirakawa Epithelial mesenchy more

Websites Kinase Inhibitors