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Light scattering for the masses! The world's leading manufacturer of DAWN and miniDAWN multi-angle light scattering (MALS) instruments for determining the absolute molar masses and sizes of polymers and biopolymers in solution. These detectors, and Wyatt's ASTRA V GPC software, interface with an ... more
TCI Europe N.V. is the European head office of Tokyo Chemical Industry Co., Ltd., a leading Japanese manufacturer of specialised and bulk chemicals. The product portfolio contains more than 22000 products including several thousand products unique to TCI. The majority of these chemicals are manu ... more
Shimadzu is a world-leading manufacturer of analytical instrumentation. Shimadzu develops and manufactures innovative products for laboratories in industry, science and governmental institutions. With our customer-oriented strategy and our high-quality service, we strive to be Europe's market le ... more
The ProteCol™ HPLC column range from SGE features proprietary column designs, incorporating inert materials throughout the flow path, the highest more
EcoSEC is a compact all–in–one system for high throughput analysis of natural or synthetic polymers by semi-micro gel permeation chromatography (GPC/SEC) more
With Merck Millipore’s new Chromolith® HighResolution columns, high resolution separations can be carried out easily more
With the new HPLC Column Configurator you find the HPLC Column you are looking for. Compare Columns of over 20 manufacturers from Agilent to Waters more
Shimadzu, one of the worldwide leading manufacturers in analytical instrumentation, has broken new grounds with the introduction of its News App for iPhone and iPod touch more
The MAESTRO software enables efficient and reliable automated sample preparation and sample introduction for GC/MS and LC/MS in a very simple manner: By mouse-click more
With almost 300 pages this catalogue covers the complete range of products of SGE: GC/HPLC columns, syringes, accessories and supplies for different more
Chiral Technologies Europe offers the largest portfolio of chiral phases available: immobilised and coated polysaccharides, protein-based, crown ethers and ion-exchange columns more
With the VICI Valco/Cheminert catalogue covers the complete range of valves and consumables for Chromatography, FIA, SFE and SFC more
For anyone developing a chiral compound, Chiral Technologies Europe (CTE) will assist with the separation and isolation of the individual enantiomers. Our contract separation service, based in our laboratories in Illkirch, offers the capabilities and expertise to separate chiral compounds into the individual isomers for Pharmaceutical, Flavour & Fragrance and Plant Protection companies more
Get the instrument you need without waiting for an investment budget! From 1 to 60 months, from one module to a complete system, whether to react on punctual needs or to strategically finance your equipment, you will find the right rental solution with us more
CHIRAL TECHNOLOGIES EUROPE has launched a re-designed website and published a new downloadable catalogue. The new site includes more user-friendly navigation to locate resources on chiral separation science and applications, products, services and news more
Substantial differences exist in the caffeine and chlorogenic acid contents of espresso coffees that can result in over-consumption by consumers at risk of caffeine toxicity, say scientists in the UK. The team carried out high performance liquid chromatography analysis of 20 commercial espresso coff more
Agilent Technologies Inc. announced that it was awarded a U.S. patent for the process used to apply the superficially porous shell to particles in Agilent Poroshell 120 high-performance liquid chromatography (HPLC) columns.The patent was issued for the unique coacervation process used to manufacture more
Agilent Technologies Inc. announced the opening of its new life sciences instruments manufacturing facility in Singapore. The facility will produce the company’s Liquid Chromatography/Mass Spectrometry (LC/MS) instruments for the global market. “The opening of the LC/MS manufacturing facility marks more
As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more
Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised upstream productivity in the production of recombinant proteins. Increased titres of up to 10 g/l stress the need for highly efficient and robust downstream processes (DSP). Most industrial bioprocess development groups apply generic DSP platforms that are designed to purify various candidates of the same class of proteins applying the same process design. Besides various filtration and virus inactivation steps, they usually involve two or three chromatographic unit operations with orthogonal separation modes. The use of high capacity chromatographic resins can help to overcome the DSP bottleneck by increasing process throughput and robustness more
One of the most widely used water-soluble polymers is Polyvinylpyrrolidone (PVP). For more than 70 years it is applied in a variety of applications in medicine, pharmacy, cosmetics and industrial production. PVP binds to polar molecules exceptionally well. It supports the solubility of tablets in water, makes the glue stick adhesive and plays an essential role in the production of membranes. In ceramic, paper and dye applications, it produces visual effects such as gloss and brilliancy. As a food additive, PVP is a stabilizer (E1201). A characteristic feature of a certain polymer is its molecular weight distribution curve, which is usually obtained by SEC Analysis more
The capabilities of a high‐resolution (HR), accurate mass spectrometer (Exactive‐MS) operating in full scan MS mode was investigated for the quantitative LC/MS analysis of drugs in patients' plasma samples. A mass resolution of 50 000 (FWHM) at m/z 200 and a mass extracted window of 5 ppm around t more
RATIONALE The metabolism of methylprednisolone is revisited in order to find new metabolites that could be important for distinguishing between different routes of administration. Recently developed liquid chromatography/tandem mass spectrometry (LC/MS/MS) strategies for the detection of cortico more
RATIONALE Fluorinated surfactants are being explored as mass spectrometry (MS)‐friendly alternatives to sodium dodecyl sulfate (SDS) for proteome analysis. Previous work demonstrates perfluorooctanoic acid (PFOA) to be compatible with electrospray ionization (ESI)‐MS. The high volatility of PFOA more
Online SPE extraction About us About Spark Contact us Distributors News Spark Holland B.V. Announces New Partnership to Increase Product Offerings, Support in North America - 21 may 2010 Pictures and presentations 2009 User Group Meeting published - 05 oct 2009 Program User Group Meeting 2009 announ more
ABOUT US PRODUCTS PRINCIPALS SERVICES SUPPORT CAREERS CONTACT US Spectrum Since 1970, Spectrum Laboratories has developed and manufactured innovative products for bioseparation and cell line management. Spectrum products are used for the filtration, isolation, purification and concentration of pha more
Library | Presentations High Throughput Analysis of Amphetamines in Urine with On-line-Solid Phase Extraction-Liquid-Chromatography-Tandem Mass Spectrometry Author(s): Maria del Mar Ramirez Fernandez, National, Institute of Criminalistics and Criminology, Brussels, Belgium Published: European Us more
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Fast protein liquid chromatography Fast Protein Liquid Chromatography, usually referred to as FPLC, is a form of column chromatography used to separate or purify proteins from complex mixtures by using Ion Chromatography . It is very commonly ... more
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