My watch list
my.chemeurope.com  
Login  

Eurofins Medigenomix / MWG Biotech sequence Wacker Chemie AG's bacterial protein production strain

29-May-2007

Eurofins Medigenomix GmbH / MWG Biotech AG have finalised a genome sequencing project with Wacker Chemie AG for the analysis of the genetic differences between Wacker's proprietary industrial protein production E. coli strain and its corresponding parental strain. The successful sequencing is an important step to further improve and advance Wacker's E.coli strain and the related proprietary E. coli secretion system, which is a well-established technology for cost-efficient production of proteins.

The genome of the E.coli strain was sequenced with ultra parallel shotgun sequencing using GS 20 technology, a high-throughput automated DNA sequencing system. The sequence reads have been assembled into contigs, i.e. sets of overlapping DNA segments, and subsequently analysed with MWG's proprietary genome comparison tool and displayed with the MWG's Annotation Viewer software.

"We are very impressed by the rapid and precise analysis of our E. coli production strain. The results will help us to further improve the performance of our production strain immensely", states Günter Wich, Head of the Biotechnology Department of Wacker Chemie AG's corporate R&D. "In addition, the further increase of efficiency will result in even more favourable cost of goods which we can offer to our customers. This is a key advantage over conventional protein production systems."

Wacker's E. coli secretion system is a commercialized and well-established technology for protein production. The core of the technology is Wacker's proprietary E. coli K12 strain, which is capable of secreting a vast variety of different recombinant proteins in their native form into the fermentation broth during cultivation, according to the company.

Facts, background information, dossiers
  • Wacker Chemie
  • MWG Biotech
  • Eurofins
  • recombinant proteins
  • proteins
  • genome sequencing
  • DNA sequencing
  • biotechnology
More about MWG Biotech
  • News

    Eurofins Medigenomix / MWG Biotech sequence Wacker Chemie AG's bacterial protein production strain

    Eurofins Medigenomix GmbH / MWG Biotech AG have finalised a genome sequencing project with Wacker Chemie AG for the analysis of the genetic differences between Wacker's proprietary industrial protein production E. coli strain and its corresponding parental strain. The successful sequencing ... more

    New RoboSeq 2500 DT automated biosystem for molecular biology applications

    With the new fully automated lab robot RoboSeq 2500 DT Disposable Tips, MWG-Biotech announces the official commercialization of the latest member of its successful series of Automated Biosystems. The new system was officially launched on Biotechnica in Hanover at the beginning of Octobe ... more

    MWG-Biotech - Pan® Oligo Sets to make your own DNA chip

    Pan® Oligo Sets is the brand name for MWG-Biotech’s new oligonucleotide sets that enable customers to produce their own oligonucleotide microarrays (DNA chips). The sets are based on the competence and the success of MWG-Biotech’s Pan® Array series of catalogue DNA chips and on the high ... more

  • Companies

    MWG Biotech AG

    MWG Biotech is an international provider of genomics products and services in DNA Oligonucleotide Synthesis, siRNA Synthesis, and DNA Sequencing. With strong customer orientientation, fast, web-based service and high quality products we provide the basis for success in the life sciences for ... more

More about Wacker Chemie
  • News

    WACKER Opens New Production Site for Silicones in South Korea

    Wacker Chemie AG opened a new production site for silicone elastomers in South Korea. The plant is located around 100 kilometers southeast of Seoul at Jincheon, where the Group has already been producing silicone sealants since 2010 and specialty silicones for the electronics industry since ... more

    Wacker opens a new plant for functional silicone fluids in India

    Wacker Metroark Chemicals Pvt. Ltd. is expanding its existing silicone production at its Amtala site near Kolkata with a new hydrosilylation plant for manufacturing functional silicone fluids. The plant with an annual capacity of over 6,000 metric tons was officially opened at a ceremony in ... more

    WACKER expects further sales and earnings growth for 2018

    As already reported, Wacker Chemie AG met or surpassed its own projections for all its performance indicators in 2017. On presenting its annual report, the Munich-based chemical company announced that Group sales reached €4.92 billion, up 6 percent year over year (2016: €4.63 billion). The ... more

  • Companies

    Wacker Chemie AG

    WACKER is a globally operating chemical company headquartered in Munich, Germany. Its portfolio focuses on silicone chemistry, polymer chemistry, fine chemicals and biotech products, polysilicon, wafers and hyperpure silicon monocrystals. In line with these core areas of expertise, WACKER h ... more

More about Eurofins
More about Wacker Biotech
  • News

    Wacker Expands Biologics Operation in Jena, Germany

    Wacker is strengthening its biopharmaceutical operations in Jena, Germany. The Munich-based chemical Group is investing around EUR15 million in this undertaking, which involves the GMP expansion of its Jena production facility and the construction of a new building there for process develop ... more

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE