Protein Structure

News Protein Structure

• Search for Advanced Materials Aided by Discovery of Hidden Symmetries in Nature

  A new way of understanding the structure of proteins, polymers, minerals, and engineered materials was published in Nature Materials. The discovery by two Penn State University researchers is a new type of symmetry in the structure of materials, which the researchers say greatly expands the possibil more

• Designer molecule detects tiny amounts of cyanide, then glows
  

  A small molecule designed to detect cyanide in water samples works quickly, is easy to use, and glows under ultraviolet or "black" light. Although the fluorescent molecule is not yet ready for market, its Indiana University Bloomington creators report in the Journal of the American Chemical Society more

• Unlike rubber bands, molecular bonds may not break faster when pulled

  From balloons to rubber bands, things always break faster when stretched. Or do they? University of Illinois scientists studying chemical bonds now have shown this isn't always the case, and their results may have profound implications for the stability of proteins to mechanical stress and the desig more

Publications Protein Structure

• The glyoxalase pathway: the first hundred yearsEllipsis and beyond

  The discovery of the enzymatic formation of lactic acid from methylglyoxal dates back to 1913 and was believed to be associated with one enzyme termed ketonaldehydemutase or glyoxalase, the latter designation prevailed. However, in 1951 it was shown that two enzymes were needed and that glutathione more

• A Microfluidic Approach for Protein Structure Determination at Room Temperature via on-chip Anomalous Diffraction

  We report a microfluidic approach for de novo protein structure determination via crystallization screening and optimization, as well as on-chip X-ray diffraction data collection. The structure of phosphonoacetate hydrolase (PhnA) has been solved to 2.11Å via on-chip collection of anomalous data tha more

• Unconventional Interaction Forces in Protein and Protein-ligand Systems and their Impacts to Drug Design

  Abstract: In drug design and enzyme engineering, the information of interactions between receptors and ligands is crucially important. In many cases, the protein structures and drug-target complex structures are determined by a delicate balance of several weak molecular interaction types. A more

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