Proteins

Companies Proteins

Wyatt Technology Europe GmbH, Germany

Light scattering for the masses! The world's leading manufacturer of DAWN and miniDAWN multi-angle light scattering (MALS) instruments for determining the absolute molar masses and sizes of polymers and biopolymers in solution. These detectors, and Wyatt's ASTRA V GPC software, interface with any s more

Biaffin GmbH & Co KG, Germany

Biaffin provides high quality services primarily specialising in biomolecular interaction analysis (BIA) using modern biosensors (Biacore). The application of biosensors based on surface plasmon resonance (SPR) allows monitoring of molecular interactions in real-time. Fast and accurate detection of more

Products Proteins

Separate proteins faster

Proteins can be analyzed or purified up to 3x faster with pressure-resistant glass columns of KNAUER Bioline and specially reinforced agarose media more

Catalogues Proteins

Everything you need to know about gel filtration on TSKgel HPLC columns

Tosoh Bioscience, a leading supplier of SEC technology, presents a new brochure featuring the use of TSKgel columns for SEC with aqueous mobile phases more

News Proteins

• Sometimes less is more
  

  The harder you pull, the quicker it goes. At least, that used to be the rule in mechanochemistry, a method that researchers apply to set chemical reactions in motion by means of mechanical forces. However, as chemists led by Professor Dominik Marx, Chair of Theoretical Chemistry at the Ruhr-Universi more

• Luminous bacterial proteins detect chemicals in water
  

  While residual medications don’t belong in the water, trace metals from industrial process waters handled by the recycling industry are, in contrast, valuable resources. Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) have developed a simple color sensor principle which facilitates the more

• Nano-tattoos for bespoke surface design

  Research reports a new strategy for using atomic force microscopy (AFM) coupled with homogeneous catalysis to carry out chemical reactions that have been ‘tattooed’ onto a material surface. Researchers in France immobilised a homogeneous transition metal catalyst onto an AFM probe and used it to per more

White papers Proteins

• Do you see the complete picture?
  

  Gel permeation chromatography (GPC) or also named size exclusion chromatography (SEC) is the most often used method for determining the molecular weight of natural and synthetic macromolecules. One specific strength of this method lies in the fact that by the separation process the whole molecular weight distribution is obtained. The molecular weight distribution contains much larger information for the characterization of polymer samples compared to a single value. more

• Sniffing Out the Secrets of Social Behavior
  

  In his novel "Perfume - the Story of a Murderer", Patrick Süskind managed to put the power of odors into words better than anyone before him. It may be a fascinating idea, but no one will ever be able to create the perfect fragrance that makes a person irresistibly attractive. In the animal world, on the other hand, olfactory signals are an essential element of social communication. Yet we are only just beginning to understand the complexities and functional differences of the sense of smell in mammals. Professor Marc Spehr is leading the Department of Chemosensation at RWTH Aachen University since 2009, where he is conducting research on the neuronal mechanisms of olfactory perception and signal processing using the mouse model. In his experiments, he and his team are trying to find out how substances for social interaction are perceived and how this perception generates a specific type of behavior more

• Characterizing Biotherapeutics with HPLC
  

  As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

Job offers Proteins

• Professor (W3) in Pharmaceutical Chemistry (f/m)
  

  The Faculty of Biochemistry, Chemistry and Pharmacy, Institute of Pharmaceutical Chemistry, at Johann Wolfgang Goethe-University Frankfurt invites applications for a full-time position as Professor (W3) in Pharmaceutical Chemistry with dedication to Medicinal Chemistry We are seeking to appoint more

• Associate Professor (W2) in Biochemistry (f/m)
  

  The Faculty of Mathematics and Natural Sciences at the University of Cologne invites applications for a tenured position as an Associate Professor (W2) in Biochemistry to be filled by March 1, 2014. Teaching of biochemistry is expected at all levels of the relevant curricula of chemistry and biol more

Publications Proteins

• Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

  The covalent attachment of the protein ubiquitin to intracellular proteins by a process known as ubiquitylation regulates almost all major cellular systems, predominantly by regulating protein turnover. Ubiquitylation requires the co-ordinated action of three enzymes termed E1, E2 and E3, and typic more

• Evidence of a novel role for Pygopus in rRNA transcription

  Increased protein synthesis during cell proliferation is accompanied by a compensatory increase in efficient ribosome production, but the mechanisms by which cells adapt to this requirement are not fully understood. In the present study, we demonstrate evidence that Pygo (Pygopus), a protein origin more

• Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E

  The highly specific binding and uptake of BoNTs (botulinum neurotoxins; A-G) into peripheral cholinergic motoneurons turns them into the most poisonous substances known. Interaction with gangliosides accumulates the neurotoxins on the plasma membrane and binding to a synaptic vesicle membrane prote more

Websites Proteins