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Tributyl acetyl citrate (TBAC), a widely-used “green” plasticizer, has been extensively applied in products for daily use. In this paper, a variety of analytical tools including sum frequency generation vibrational spectroscopy (SFG), coherent anti-Strokes Raman spectroscopy (CARS), contact ... more
A stable system of enantioselectively recognising L-tryptophan based on ß-cyclodextrin-modified single nanochannel fabricated in a polyimide membrane was demonstrated, which is the first time to realize chiral recognition of essential amino acid with this systems. more
We report a simple, effective method to assess the cytosolic delivery efficiency and kinetics of cell-penetrating peptides using a pH-sensitive fluorescent probe, naphthofluorescein. more
Molybdenum disulfide (MoS2) is an emerging material with some unique physical and electronic properties somewhat comparable to those of graphene. It was prepared with the use of a simple hydrothermal process, and has a layered structure similar to that of graphene. Also, it has a peroxidase ... more
A pulse of D2O vapour on the order of microseconds is allowed to react with the +6 to +9 charge states of ubiquitin confined in a linear ion trap (LIT). Two envelopes of peaks are detected for the ions of ubiquitin, corresponding to the ions that exchange more quickly and more slowly. The d ... more
Molybdenum disulfide (MoS2) is an emerging material with some unique physical and electronic properties somewhat comparable to those of graphene. It was prepared with the use of a simple hydrothermal process, and has a layered structure similar to that of graphene. Also, it has a peroxidase ... more
An automatable, robust, high-performance online multidimensional liquid chromatography (MDLC) platform comprising of pH 10 reversed-phase (RP), strong cation exchange (SCX), and pH 2 RP separation stages has been integrated into a modified commercial off-the-shelf LC instrument with a simpl ... more
In this study, ofloxacin stereoisomers were chosen as a simple model to investigate the stereospecific recognition of chiral haptens and antibodies. Three polyclonal antibodies were studied and showed a relatively high enantioselectivity and an excellent sensitivity. Comparative molecular f ... more
Several heritage systems have been studied using state-of-the-art synchrotron techniques. The cultural heritage value of silver is documented in museum collections across the globe. However, the silver surface is not as chemically stable as that of other precious metals, and is susceptible ... more
Metastatic melanomas are frequently refractory to most adjuvant therapies such as chemotherapies and radiotherapies. Recently, immunotherapies have shown good results in the treatment of some metastatic melanomas. Immune cell infiltration in the tumor has been associated with successful imm ... more
Tributyl acetyl citrate (TBAC), a widely-used “green” plasticizer, has been extensively applied in products for daily use. In this paper, a variety of analytical tools including sum frequency generation vibrational spectroscopy (SFG), coherent anti-Strokes Raman spectroscopy (CARS), contact ... more
A stable system of enantioselectively recognising L-tryptophan based on ß-cyclodextrin-modified single nanochannel fabricated in a polyimide membrane was demonstrated, which is the first time to realize chiral recognition of essential amino acid with this systems. more
We report a simple, effective method to assess the cytosolic delivery efficiency and kinetics of cell-penetrating peptides using a pH-sensitive fluorescent probe, naphthofluorescein. more
A pulse of D2O vapour on the order of microseconds is allowed to react with the +6 to +9 charge states of ubiquitin confined in a linear ion trap (LIT). Two envelopes of peaks are detected for the ions of ubiquitin, corresponding to the ions that exchange more quickly and more slowly. The d ... more
A novel hyaluronic acid modified transfersome was prepared to deliver drugs to lymphatics through the transdermal route. Doxorubicin loaded HA-GMS-T was able to efficiently penetrate into the deep skin tissue, leading to enhanced absorption by lymphatics. Most importantly, hyaluronic acid e ... more
Inside the USCAP Journals Laboratory Investigation 95, 2 (January 2015). doi:10.1038/labinvest.2014.152 more
Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract Laboratory Investigation advance online publication, December 22 2014. doi:10.1038/labinvest.2014.162 Authors: Gail H Leeming, Anja Kipar, D ... more
Serum amyloid A and inflammation in diabetic kidney disease and podocytes Laboratory Investigation advance online publication, December 22 2014. doi:10.1038/labinvest.2014.163 Authors: Robert J Anderberg, Rick L Meek, Kelly L Hudkins, Sheryl K Cooney, Charles E Alpers, Renee C ... more
Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic Laboratory Investigation advance online publication, December 15 2014. doi:10.1038/labinvest.2014.157 Authors: Daniel E Carvajal-Hausdorf, Kurt A Schalper, Veronique M Neumeister & David L Rimm more
Inside the USCAP Journals Laboratory Investigation 94, 1310 (December 2014). doi:10.1038/labinvest.2014.137 more
Abstract Mn‐doped La0.8Sr0.2CoO3 perovskite oxides (La0.8Sr0.2Co1–xMnxO3; x = 0, 0.1, 0.3, 0.5) were synthesized by a modified sol‐gel method. The phase‐pure oxides were obtained. CoO and carbonates were formed on the surface of La0.8Sr0.2CoO3. With increasing doping content, these impur ... more
Abstract In a laminated‐sheet microchannel reactor, several microchannel sheets with the same or different structures are mutually laminated together. The effect of microchannel and manifold structure as well as the number of laminated sheets on the velocity distribution among microchann ... more
Abstract The commercial computational fluid dynamics software FLUENT was used to simulate the flow and chemical reaction process of a honeycombed SCR DeNOx catalyst. In the calculation model, the porous medium model was applied to describe the wall body region of the honeycombed catalyst ... more
Generally, process safety automation has been considered to be the responsibility of a specialized safety system and that remains true for Safety Integrity Level safety automation requirements. But, what if the basic automation of the process could be constructed in such a way that it signi ... more
Graphene platelets were synthesized from pencil flake graphite and commercial graphite by chemical method. The chemical method involved modified Hummer's method to synthesize graphene oxide (GO) and the use of hydrazine monohydrate to reduce GO to reduced graphene oxide (rGO). rGO were furt ... more
Consumers assess their tap water primarily by its taste, odor, and appearance. Starting in 1979, USEPA promulgated Secondary Maximum Contaminant Levels (SMCLs) as guidance for contaminants with organoleptic effects and also to maintain consumers’ confidence in tap water. This review assesse ... more
Environmental hypoxia can occur in both natural and occupational environments. Over the recent years, the ability of hypoxia to cause endocrine disruption via perturbations in steroid synthesis (steroidogenesis) has become increasingly clear. To further understand the molecular mechanism un ... more
Over the past decades, China has been suffering from negative environmental impacts from distempered e-waste recycling activities. After a decade of effort, disassembly and raw materials recycling of environmentally friendly e-waste have been realized in specialized companies, in China, and ... more
Sanitizing human and animal waste (e.g., urine, fecal sludge, or grey water) is a critical step in reducing the spread of disease and ensuring microbially safe reuse of waste materials. Viruses are particularly persistent pathogens and can be transmitted through inadequately sanitized waste ... more
Aerosol samples were collected from Tsukuba, Japan, soon after the 2011 Fukushima nuclear accident and analyzed for speciation of radiocesium and radioiodine to explore their chemical behavior and isotopic ratios after the release. Most 134Cs and 137Cs were bound in organic matter (53–91%) ... more
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