Nature Protocols 12, 1198 (2017).
Authors: Joerg Schnitzbauer, Maximilian T Strauss, Thomas Schlichthaerle, Florian Schueder & Ralf Jungmann
Super-resolution techniques have begun to transform biological and biomedical research by allowing resea ... more
Due to the lowered pKa of 4-fluorohistidine relative to histidine, peptides and proteins containing this amino acid are potentially endowed with novel properties. We report here the optimized synthesis of 4-fluorohistidine and show that it can efficiently replace histidine in in vitro trans ... more
This paper describes the rational search for and the synthesis of eight new polymorphs, solvates or hydrates of the well-known drug nifuroxazide. By selecting the appropriate polymorph, a 50% increase in solubility was obtained, compared to the commercially available solid form. The target ... more
Modern pulsed X-ray sources permit time-dependent measurements of dynamical changes in atoms and molecules via non-resonant scattering. The planning, analysis, and interpretation of such experiments, however, require a firm and elaborated theoretical framework. This paper provides a detaile ... more
Transformation of biomass into liquid fuels is of great importance. Previous work has demonstrated the ability of specific ionic liquids (ILs), such as 1-ethyl-3-methylimidazolium acetate ([C2C1Im][OAc]), and cholinium lysinate ([Ch][Lys]), to be effective biomass pretreatment solvents. Usi ... more