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Publications

Search for science publications by its title or author and refine your search on the basis of publishing houses, year etc.

Current publications

Super-resolution microscopy with DNA-PAINT

Nature Protocols 12, 1198 (2017). doi:10.1038/nprot.2017.024 Authors: Joerg Schnitzbauer, Maximilian T Strauss, Thomas Schlichthaerle, Florian Schueder & Ralf Jungmann Super-resolution techniques have begun to transform biological and biomedical research by allowing resea ... more

Genetic incorporation of 4-fluorohistidine into peptides enables selective affinity purification

Due to the lowered pKa of 4-fluorohistidine relative to histidine, peptides and proteins containing this amino acid are potentially endowed with novel properties. We report here the optimized synthesis of 4-fluorohistidine and show that it can efficiently replace histidine in in vitro trans ... more

Bringing new life into old drugs. A case study on nifuroxazide polymorphism

This paper describes the rational search for and the synthesis of eight new polymorphs, solvates or hydrates of the well-known drug nifuroxazide. By selecting the appropriate polymorph, a 50% increase in solubility was obtained, compared to the commercially available solid form. The target ... more

Time-Resolved X-Ray Scattering by Electronic Wave Packets: Analytic Solutions to the Hydrogen Atom

Modern pulsed X-ray sources permit time-dependent measurements of dynamical changes in atoms and molecules via non-resonant scattering. The planning, analysis, and interpretation of such experiments, however, require a firm and elaborated theoretical framework. This paper provides a detaile ... more

One-pot integrated biofuel production using low-cost biocompatible protic ionic liquids

Transformation of biomass into liquid fuels is of great importance. Previous work has demonstrated the ability of specific ionic liquids (ILs), such as 1-ethyl-3-methylimidazolium acetate ([C2C1Im][OAc]), and cholinium lysinate ([Ch][Lys]), to be effective biomass pretreatment solvents. Usi ... more

All publications

Paper Microfluidics for Nucleic Acids Amplification Testing (NAAT) of Infectious Diseases

The diagnosis of infectious diseases is entering a new and interesting phase. Technologies based on paper microfluidics, coupled to developments in isothermal amplification of Nucleic Acids (NA) raise opportunities for bringing the methods of molecular biology in the field, in low settings ... more

Online measurement of photoisomerisation efficiency in solution using ion mobility mass spectrometry

The photoisomerisation of charged molecules in solution is probed directly using ion mobility mass spectrometry with electrospray ionisation. The technique is demonstrated using a prototype azoheteroarene cation in methanol. By scanning the wavelength of the excitation light while monitorin ... more

Finding a Helix in a Haystack: Nucleic Acid Cytometry with Droplet Microfluidics

Nucleic acids encode the information of life, programming cellular functions and dictating many biological outcomes. Differentiating between cells based on their nucleic acid programs is, thus, a powerful way to unravel the genetic bases of many phenotypes. This is especially important cons ... more

A droplet-chip/mass spectrometry approach to study organic synthesis at nanoliter scale

A droplet-based microfluidic device with seamless hyphenation to electrospray mass spectrometry was developed to rapidly investigate organic reactions in segmented flow providing a versatile tool for drug development. A chip-MS interface with an integrated counterelectrode allowed for a fle ... more

Electrochemiluminescence Behavior of AgNCs and Its Application in Immunosensor based on PANI/PPy-Ag dendrites modified electrode

In this paper, hyperbranched polyethyleneimine-protected silver nanoclusters (hPEI-AgNCs) with excellent electrochemiluminescence (ECL) emission in the presence of coreactant K2S2O8 was prepared by chemical reduction of silver ions (silver nitrate) coordinated with dendrigraft polymer, and ... more

All publications on analytics

Genetic incorporation of 4-fluorohistidine into peptides enables selective affinity purification

Due to the lowered pKa of 4-fluorohistidine relative to histidine, peptides and proteins containing this amino acid are potentially endowed with novel properties. We report here the optimized synthesis of 4-fluorohistidine and show that it can efficiently replace histidine in in vitro trans ... more

Bringing new life into old drugs. A case study on nifuroxazide polymorphism

This paper describes the rational search for and the synthesis of eight new polymorphs, solvates or hydrates of the well-known drug nifuroxazide. By selecting the appropriate polymorph, a 50% increase in solubility was obtained, compared to the commercially available solid form. The target ... more

Time-Resolved X-Ray Scattering by Electronic Wave Packets: Analytic Solutions to the Hydrogen Atom

Modern pulsed X-ray sources permit time-dependent measurements of dynamical changes in atoms and molecules via non-resonant scattering. The planning, analysis, and interpretation of such experiments, however, require a firm and elaborated theoretical framework. This paper provides a detaile ... more

One-pot integrated biofuel production using low-cost biocompatible protic ionic liquids

Transformation of biomass into liquid fuels is of great importance. Previous work has demonstrated the ability of specific ionic liquids (ILs), such as 1-ethyl-3-methylimidazolium acetate ([C2C1Im][OAc]), and cholinium lysinate ([Ch][Lys]), to be effective biomass pretreatment solvents. Usi ... more

A dsDNA model optimized for electrokinetic applications

We present a coarse-grained (CG) model of a charged double-stranded DNA immersed in an electrolyte solution that can be used for a variety of electrokinetic applications. The model is based on an earlier rigid and immobile model of Weik et al. and includes now semi-flexibility and mobility, ... more

All publications on chemistry

Inside the USCAP Journals

Inside the USCAP Journals Laboratory Investigation 97, 492 (May 2017). doi:10.1038/labinvest.2017.38 more

The evolving concept of cancer stem-like cells in thyroid cancer and other solid tumors

The evolving concept of cancer stem-like cells in thyroid cancer and other solid tumors Laboratory Investigation advance online publication, April 10 2017. doi:10.1038/labinvest.2017.41 Authors: Heather Hardin, Ranran Zhang, Holly Helein, Darya Buehler, Zhenying Guo & Ricardo ... more

Inside the USCAP Journals

Inside the USCAP Journals Laboratory Investigation 97, 354 (April 2017). doi:10.1038/labinvest.2017.27 more

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy Laboratory Investigation advance online publication, March 27 2017. doi:10.1038/labinvest.2017.25 Authors: Robert Sackstein, Tobias Schatton & Steven R Barthel more

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology Laboratory Investigation advance online publication, March 6 2017. doi:10.1038/labinvest.2017.9 Authors: Akinori Kawakami & David E Fisher more

All publications on lab technology

Influence of epoxy addition on the thermal, mechanical, and dielectrical properties of polycyanurate films

In the study, polycyanurate (PCN)/epoxy resin (ER) blends are prepared to enhance the physical properties of cyanate ester resins. The effects of curing schedule and blend composition on their thermal, mechanical, and dielectrical properties of cured PCN/epoxy blend films are examined. FTIR ... more

Production of doxycycline‐loaded gelatin microspheres through thermal treatment in inverse suspensions

Doxycycline is a broad‐spectrum antibiotic. The development of a polymer matrix that can allow for the controlled release of this drug can bring many benefits to veterinary and human medicine. For this reason, in the present study doxycycline was encapsulated in situ with gelatin through th ... more

Absorption and Desorption of Carbon Dioxide in Several Water Types

Abstract This study investigated the effect of water type on the rate of CO2 transfer from/to an aqueous phase with varying degree of water salinity. The absorption and desorption experiments were conducted on reverse osmosis product, brackish well, and brackish water reverse osmosis re ... more

Experimental evaluation and modeling of thermal conductivity of tetrafunctional epoxy resin containing different carbon nanostructures

This study attempts to investigate the thermal conductivity behavior of epoxy nanocomposites containing different types of nanofillers, such as 1‐D Multiwall Carbon Nanotubes (MWCNTs) and 2‐D predominant shape of Exfoliated Graphite nanoparticles (EG) at loading level from 0.25 to 3% wt. Fo ... more

A new paradigm for accident investigation and analysis in the era of big data

The advent of the era of Big Data has spawned a new research paradigm and has transformed the outlook of numerous fields in science and engineering. Similarly, as one of the important fields of safety science, the area of accident investigation also has great opportunities for leveraging Bi ... more

All publications on chemical engineering

Comparison of PM2.5 carbonaceous pollutants between an urban site in Shanghai and a background site in a coastal East China Sea island in summer: concentration, composition and ...

Nine paired samples of atmospheric particulate matter with an aerodynamic diameter less than or equal to 2.5 μm (PM2.5) were collected concurrently from an urban site in Shanghai, China and a background site in Huaniao Island (HNI) in the coastal East China Sea (ECS) between July 21 and 29, ... more

Soil sorption of two nitramines derived from amine-based CO2 capture

Nitramines are potentially carcinogens that form from the amines used in post-combustion CO2 capture (PCCC). The soil sorption characteristics of monoethanol (MEA)- and dimethyl (DMA)-nitramines have been assessed using a batch experimental setup, and defined indirectly by measuring loss of ... more

An Oil Spill Decision Matrix in Response to Surface Spills of Various Bitumen Blends

Canada’s production, transport, and sale of diluted bitumen (dilbit) products are expected to increase by a million barrels per day over the next decade. The anticipated growth in oil production and transport increases the risk of oil spills in aquatic areas and places greater demands on oi ... more

Photolysis and cellular toxicities of the organic ultraviolet filter chemical octyl methoxycinnamate and its photoproducts

Organic ultraviolet (UV) filter chemicals are the active ingredients used in many sunscreens to protect the skin from UV light; these chemicals have been detected in numerous aquatic environments leading to concerns about how they might affect aquatic organisms and humans. One commonly used ... more

Sustainability, Vol. 9, Pages 852: Sustainable Use of Reservoir Sediment through Partial Application in Building Material

Sediment, often considered a by-product of various activities within river basin management to be disposed of, or a pollutant to be controlled, is increasingly being acknowledged as a resource in need of management. The paper deals with the possibility of reusing sediment from two Slovak re ... more

All publications on environmental technology
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