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Translation complex profile sequencing to study the in vivo dynamics of mRNA–ribosome interactions during translation initiation, elongation and termination

Nature Protocols 12, 697 (2017). doi:10.1038/nprot.2016.189

Authors: Nikolay E Shirokikh, Stuart K Archer, Traude H Beilharz, David Powell & Thomas Preiss

Messenger RNA (mRNA) translation is a tightly controlled process that is integral to gene expression. It features intricate and dynamic interactions of the small and large subunits of the ribosome with mRNAs, aided by multiple auxiliary factors during distinct initiation, elongation and termination phases. The

Authors:   Nikolay E Shirokikh; Stuart K Archer; Traude H Beilharz; David Powell; Thomas Preiss
Journal:   Nature Protocols
Volume:   12
edition:   4
Year:   2017
Pages:   697
DOI:   10.1038/nprot.2016.189
Publication date:   01-Apr-2017
Facts, background information, dossiers
  • interactions
  • sequencing
  • messenger RNA
More about Nature Publishing Group
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