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15N isotopic labelling for in-cell protein studies by NMR spectroscopy and single-cell IR Synchrotron Radiation FTIR Microscopy: a correlative study

The ultimate goal of modern structural biology is to probe proteins structure and dynamics in their physiological microenvironment. In-cell NMR spectroscopy is an ideal technique for achieving this goal, being able to investigate proteins at atomic-resolution in living cells. The reliability of the results p

Authors:   Elisa Mitri; Letizia Barbieri; Lisa Vaccari; Enrico Luchinat
Journal:   Analyst
DOI:   10.1039/C7AN01464C
Facts, background information, dossiers
  • structural biology
  • Single
  • cells
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