Copper-Catalyzed Direct Amination of Halo(hetero)arenes with Sodium Azide as the Amino Source

Abstract:

In the synthesis of primary (hetero)aryl amines through copper-catalysis, the ammonia surrogates or aqueous ammonia nucleophilic partners can be replaced by sodium azide. Recent efforts in copper-mediated transformation of (hetero)aryl halides to (hetero) aryl amines using azide anion as the amino source are discussed in these highlights.

Authors:		Messaoudi, S.; Brion, J.-D.; Alami, M.
Journal:		Mini-Reviews in Organic Chemistry
DOI:		10.2174/157019311797440236

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