Although nano-structured surfaces exhibit superior biological activities to the smooth or micro-structured surfaces, whether there is an optimal topographical surface in nano-scale affecting protein adsorption and cell behaviors is still controversial. In this study, porous aluminum oxide membranes with different pore sizes ranging from 25 to 120 nm were prepared by the anodic oxidation technique. The surface morphology, topography and wettability were analyzed by scanning electron microscope, atomic force microscope and water contact angle measurement, respectively. The results indicated that the synergistic action of the nano-topography structure and hydrophilic/hydrophobic properties resulted in a highest protein adsorption on the aluminum oxide membrane with 80 nm pore size. Additionally, the morphological, metabolic and cell counting methods showed that cells had different sensitivity to porous aluminum oxide membranes with different surface features. Furthermore, this sensitivity was cell type dependent. The optimal pore size of aluminum oxide membranes for cell growth was 80 nm for PC12 cells and 50 nm for NIH 3T3 cells.
Hua-Jie Wang, Yuan-Yuan Sun, Ying Cao, Kui Wang, Lin Yang, Yi-Dong Zhang, Zhi Zheng
Plant parasitic nematodes are the most destructive group of plant pathogens worldwide and their control is extremely challenging. Plant Essential oils (EOs) and their constituents have a great potential in nematode control since they can be developed for use as nematicides themselves or can ... more
For over a century, ulcer has been a major cause of morbidity and mortality. Its treatment has progressed from vagotomy to proton pump inhibitors. However, the drugs used produce many adverse effects and are less effective than they ought to be. Therefore, there is a growing interest in alt ... more
Endophytic fungi are ubiquitous organisms found in the plants, residing intercellular or intracellular, at least for a portion of their lives without causing apparent symptoms of infection. Almost all plants are known to harbor endophytes. The choice of the plant to be used for exploring en ... more
Physicists describe how they have synthesized a new material that belongs to the iron-selenide class of superconductors, called LixFe2Se2(NH3)y, in a paper about to be published in EPJ B. The work was carried out by Ernst-Wilhelm Scheidt from the University of Augsburg and colleagues. This ... more
The U.S. federal government is significantly underestimating the costs of carbon pollution because it is using a faulty analytical model, according to a new study published in the Journal of Environmental Studies and Sciences. A more appropriate accounting of costs would pave the way to cle ... more
Springer advisory board member Vladimir V. Dmitriev, along with fellow scientists Yuriy M. Bunkov and Igor A. Fomin, have been named winners of the 2008 Fritz London Memorial Prize for their discovery and understanding of the "Phase Coherent Spin Precession and Spin Superfluidity of 3He-B." ... more