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Manipulation and capture of A[small beta] amyloid fibrils and monomers by DC insulator gradient dielectrophoresis (DC-iGDEP)

Here we report a novel method for the manipulation and concentration of Aβ amyloid fibrils, implicated in Alzheimer's disease, using DC insulating gradient dielectrophoresis (DC-iGDEP). Fibril enrichment was found to be [[similar]] 400%. Simulations suggest that capture of the full range of amyloid protein agg...

Authors:   Sarah J. R. Staton; Paul V. Jones; Ginger Ku; S. Douglass Gilman; Indu Kheterpal; Mark A. Hayes
Journal:   Analyst
DOI:   10.1039/C2AN35138B

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