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Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI‐C) is used to functionalize surfaces of adeno‐associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI‐C hybrid vectors become highly “sticky”, resulting in spatially patterned viral attachment onto substrates by the simple “gene‐vector drawing” technique (see picture).
<!--Unmatched element: w:blockFixed-->| Authors: | Kim, Eunmi; Song, In Taek; Lee, Slgirim; Kim, Jung‐Suk; Lee, Haeshin; Jang, Jae‐Hyung | |
| Journal: | Angewandte Chemie International Edition | |
| Year: | 2012 | |
| Pages: | n/a | |
| DOI: | 10.1002/anie.201201495 | |
| Publication date: | 26-04-2012 |
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