my.chemeurope.com
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
Double headed acyclo-C-nucleosides, 1,4-bis(3-mercapto-1H-1,2,4-triazol-5-yl)butane-1,2,3,4-tetrol (6), 5,5’-(1,2,3,4-tetrahydroxybutane-1,4-diyl)bis(1,3,4-oxadiazole-2(3H)-thione) (7), and 1,4-bis(4-amino-5-mercapto-4H-1,2,4-triazol-3-yl)butane-1,2,3,4-tetrol (8) have been synthesized from D-glucose (1) without protecting hydroxyl groups. Two steps synthesis leading to formation of 2,3,4,5-tetrahydroxyhexanedihydrazide (4) which is regarded as starting intermediates for the synthesis of 6,7 and 8. Synthetic intermediates and final products were appropriately characterized by IR, 1H NMR and 13C NMR. The products were tested in vitro against gram positive bacteria Staphylococcus aureus, Listeria inovanii and gram negative bacteria Klebsiella pneumoniae, Salmonella sp, Escherichia coli and compared with the known antibiotic: amoxicillin + clavulanic acid (AMC) and showed variable effects.
| Authors: | Sarah Amara, Adil A. Othman | |
| Journal: | Arabian Journal of Chemistry | |
| Year: | 2012 | |
| DOI: | 10.1016/j.arabjc.2012.05.005 | |
| Publication date: | 04-06-2012 |
Watchlist
This is where you can add this publication to your personal favourites.
Additional Information
Publication date: July 2013Source:Journal of Solid State Chemistry, Volume 203 Author(s): S. Kumar , K. Singh , M. Miclau , Ch. Simon , C. Martin , A. Maignan The change from antiferromagnetism induced ferroelectricity to spin glass ferroelectric relaxor has been studied along the ... more
Investigation of an unusual low-temperature phase transformation in RbBH4 by neutron diffraction
Publication date: July 2013Source:Journal of Solid State Chemistry, Volume 203 Author(s): Brian B. Kitchen , Nina Verdal , Terrence J. Udovic , John J. Rush , Michael R. Hartman , Daniel J. DeVries To investigate the previously reported low-temperature phase transition in rubidium ... more
Effect of co-doping Tm3+ ions on the emission properties of Dy3+ ions in tellurite glasses
Publication date: July 2013Source:Journal of Solid State Chemistry, Volume 203 Author(s): T. Sasikala , L. Rama Moorthy , A. Mohan Babu , T. Srinivasa Rao The present work reports the absorption, photoluminescence and decay properties of singly doped Dy3+ and co-doped Dy3+/Tm3+ ions ... more
Elsevier Acquires the Beilstein Database
Elsevier announced the acquisition through its subsidiary MDL Information Systems GmbH, of the Beilstein Database, the world's largest compilation of chemical facts and the premier database in the field of organic chemistry. Elsevier has been exclusively involved in both the production an ... more
Über CHEMIE.DE
CHEMIE.DE Information Service GmbH runs specialist scientific internet portals. The secret to our success? We are familiar with what we publish.
Advertising at CHEMIE.DE
Our advertising formats support you in getting your message across to a clearly defined target audience.
© 1997-2013 CHEMIE.DE Information Service GmbH, All rights reserved
Netmeeting
