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Optical mapping of DNA provides large-scale genomic information that can be used to assemble contigs from next-generation sequencing, and to detect rearrangements between single cells. A recent optical mapping technique called denaturation mapping has the advantage of using physical principles rather than the actio

Authors:   Robert L. Welch; Robert Sladek; Ken Dewar; Walter W. Reisner
Journal:   Lab on a Chip
DOI:   10.1039/C2LC40504K

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  • Saccharomyces cerevisiae
  • next generation sequencing
  • cells
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