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[Report] Discovery and spectroscopy of the young jovian planet 51 Eri b with the Gemini Planet Imager

02-Oct-2015 | B. Macintosh; J. R. Graham; T. Barman; R. J. De Rosa; Q. Konopacky; M. S. Marley; C. Marois; E. L. Nielsen; L. Pueyo ..., Science , 2015

. Morzinski, R. Murray-Clay, R. Oppenheimer, D. W. Palmer, R. Patel, M. D. Perrin, L. A. Poyneer, R. R. Rafikov, F. T. Rantakyrö, E. L. Rice, P. Rojo, A. R. Rudy, J.-B. Ruffio, M. T. Ruiz, N. Sadakuni, L...


Large Hexadecametallic {MnIII–LnIII} Wheels: Synthesis, Structural, Magnetic, and Theoretical Characterization

25-Sep-2015 | Kuduva R. Vignesh, Stuart K. Langley, Boujemaa Moubaraki, Keith S. Murray, Gopalan Rajaraman, Chemistry - A European Journal, 2015

Abstract The synthesis, gas sorption studies, magnetic properties, and theoretical studies of new molecular wheels of core type {MnIII8LnIII8} (Ln=Dy, Ho, Er, Y and Yb), using the ligand mdeaH2, in the presence of ortho‐toluic or benzoic acid are reported. From the seven wheels studied the ...


B(OCH2CF3)3-mediated direct amidation of pharmaceutically relevant building blocks in cyclopentyl methyl ether

24-Sep-2015 | Valerija Karaluka; Rachel M. Lanigan; Paul M. Murray; Matthew Badland; Tom D. Sheppard, Organic & Biomolecular Chemistry, 2015

The use of B(OCH2CF3)3 for mediating direct amidation reactions of a wide range of pharmaceutically relevant carboxylic acids and amines is described, including numerous heterocycle-containing examples. An initial screen of solvents for the direct amidation reaction suggested that cyclopentyl ...


The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

24-Sep-2015 | S. Bhatt; D. J. Weiss; E. Cameron; D. Bisanzio; B. Mappin; U. Dalrymple; K. E. Battle; C. L. Moyes; A. Henry; P. A. ..., Nature, 2015

, P. A. Eckhoff, E. A. Wenger, O. Briët, M. A. Penny, T. A. Smith, A. Bennett, J. Yukich, T. P. Eisele, J. T. Griffin, C. A. Fergus, M. Lynch, F. Lindgren, J. M. Cohen, C. L. J. Murray, D. L. Smith...


Sensors, Vol. 15, Pages 24573-24584: Effect of Electrode Configuration on Nitric Oxide Gas Sensor Behavior

23-Sep-2015 | Cui, Ling ; Murray, Erica P., Sensors, 2015

The influence of electrode configuration on the impedancemetric response of nitric oxide (NO) gas sensors was investigated for solid electrochemical cells [Au/yttria-stabilized zirconia (YSZ)/Au)]. Fabrication of the sensors was carried out at 1050 °C in order to establish a porous YSZ ...


Discovery of ((4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methylpyrrolo[1,2-f][1,2,4]triazine-6-carbonyl)(propyl)carbamoyloxy)methyl-2-(4-(phosphonooxy)phenyl)acetate (BMS-751324), a Clinical Prodrug of p38α MAP Kinase Inhibitor

22-Sep-2015 | Chunjian Liu; James Lin; John Hynes; Hong Wu; Stephen T. Wrobleski; Shuqun Lin; T. G. Murali Dhar; Vivekananda M. Vr ..., Journal of Medicinal Chemistry, 2015

In search for prodrugs to address the issue of pH-dependent solubility and exposure associated with 1 (BMS-582949), a previously disclosed phase II clinical p38α MAP kinase inhibitor, a structurally novel clinical prodrug, 2 (BMS-751324), featuring a carbamoylmethylene linked promoiety containing ...


Poroelastic Foams for Simple Fabrication of Complex Soft Robots

19-Sep-2015 | Benjamin C. Mac Murray, Xintong An, Sanlin S. Robinson, Ilse M. van Meerbeek, Kevin W. O'Brien, Huichan Zhao, Robert ..., Advanced Materials, 2015

Open‐celled, elastomeric foams allow the simple design of fully 3D pneumatic soft machines using common forming techniques. This is demonstrated through fabrication of simple actuators and an entirely soft, functional fluid pump formed in the shape of the human heart. The device pumps at ...


Spectrally-Resolved Dielectric Functions of Solution-Cast Quantum Dot Thin Films

08-Sep-2015 | Benjamin T. Diroll; E. Ashley Gaulding; Cherie R. Kagan; Christopher B. Murray, Chemistry of Materials, 2015

Quantum confinement is the divergence, at small crystallite size, of the electronic structure of semiconductor nanocrystals, or quantum dots, from the properties of larger crystals of the same materials. Although the extinction properties of quantum dots in the dispersed state have been ...


The British route to innovation

01-Sep-2015 | Nature Materials, 2015

Nature Materials 14, 851 (2015). doi:10.1038/nmat4404 Richard Murray of Innovate UK explains to Nature Materials how innovation derived from research findings can boost...


Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3

31-Aug-2015 | Justin K. Murray; Yi-Xin Qian; Benxian Liu; Robin Elliott; Jennifer Aral; Cynthia Park; Xuxia Zhang; Michael Stenkil ..., Journal of Medicinal Chemistry, 2015

To realize the medicinal potential of peptide toxins, naturally occurring disulfide-rich peptides, as ion channel antagonists, more efficient pharmaceutical optimization technologies must be developed. Here, we show that the therapeutic properties of multiple cysteine toxin peptides can be ...


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