My watch list
my.chemeurope.com  
Login  

758 Newest Publications

rss

Modular design of SPIRO-OMeTAD analogues as hole transport materials in solar cells

30-Apr-2015 | Alexander Murray; Jarvist Moore Frost; Christopher Hendon; Chris D Molloy; D Carbery; Aron Walsh, Chemical Communication, 2015

We predict the ionisation potentials of the hole-conducting material SPIRO-OMeTAD and twelve methoxy isomers and polymethoxy derivatives. Based on electronic and economic factors, we identify the optimal compounds for application as p-type hole-selective contacts in hybrid halide perovskite solar ...

more

Fibroblastic Synoviocytes Secrete Plasma Proteins via α2‐Macroglobulins Serving as Intracellular and Extracellular Chaperones

21-Apr-2015 | Ke‐Wei Zhao, Elsa J. Brochmann Murray, Samuel S. Murray, Journal of Cellular Biochemistry, 2015

ABSTRACT Changes in plasma protein levels in synovial fluid (SF) have been implicated in osteoarthritis and rheumatoid arthritis. It was previously thought that the presence of plasma proteins in SF reflected ultrafiltration or extravasation from the vasculature, possibly due to retraction of ...

more

Selective Targeting of the TPX2 Site of Importin‐α Using Fragment‐Based Ligand Design

21-Apr-2015 | Rhian S. Holvey, Eugene Valkov, David Neal, Murray Stewart, Chris Abell, ChemMedChem, 2015

Abstract Protein–protein interactions are difficult therapeutic targets, and inhibiting pathologically relevant interactions without disrupting other essential ones presents an additional challenge. Herein we report how this might be achieved for the potential anticancer target, the ...

more

Defect-dependent colossal negative thermal expansion in UiO-66(Hf) metal–organic framework

15-Apr-2015 | Matthew J. Cliffe; Joshua A. Hill; Claire A. Murray; François-Xavier Coudert; Andrew L. Goodwin, Physical Chemistry Chemical Physics, 2015

Thermally-densified hafnium terephthalate UiO-66(Hf) is shown to exhibit the strongest isotropic negative thermal expansion (NTE) effect yet reported for a metal–organic framework (MOF). Incorporation of correlated vacancy defects within the framework affects both the extent of thermal ...

more

Smectic Nanorod Superlattices Assembled on Liquid Subphases: Structure, Orientation, Defects, and Optical Polarization

08-Apr-2015 | Benjamin T. Diroll; Nicholas J. Greybush; Cherie R. Kagan; Christopher B. Murray, Chemistry of Materials, 2015

Directing the orientation of anisotropic nanocrystal assemblies is important for harnessing the shape-dependent properties of nanocrystal solids in devices. We control the orientation of smectic B superlattices of CdSe/CdS dot-in-rod nanocrystals through assembly on different polar interfaces and ...

more

Cosolute Effects on Amyloid Aggregation in a Nondiffusion Limited Regime: Intrinsic Osmolyte Properties and the Volume Exclusion Principle

03-Apr-2015 | Brian Murray; Joseph Rosenthal; Zhongli Zheng; David Isaacson; Yingxi Zhu; Georges Belfort, Langmuir, 2015

The effects of cosolutes on amyloid aggregation kinetics in vivo are critical and not fully understood. To explore the effects of cosolute additives, the in vitro behavior of destabilizing and stabilizing osmolytes with polymer cosolutes on the aggregation of a model amyloid, human insulin, is ...

more

[Cu(N^N)(P^P)]+ complexes with 2,2[prime or minute]:6[prime or minute],2[prime or minute][prime or minute]-terpyridine ligands as the N^N domain

01-Apr-2015 | Niamh S. Murray; Sarah Keller; Edwin C. Constable; Catherine E. Housecroft; Markus Neuburger; Alessandro Prescimone, Dalton Transactions, 2015

The first examples of [Cu(N^N)(POP)]+ complexes (POP = bis(2-(diphenylphosphino)phenyl)ether) in which the N^N domain is a 2,2′:6′,2′′-terpyridine (tpy) ligand have been prepared and characterized; N^N = tpy, 5,5′′-dimethyl-2,2′:6′,2′′-terpyridine (1), 4′-(4-tolyl)-2,2′:6′,2′′-terpyridine (2), ...

more

Engineering Cortical Neuron Polarity with Nanomagnets on a Chip

01-Apr-2015 | Anja Kunze; Peter Tseng; Chanya Godzich; Coleman Murray; Anna Caputo; Felix E. Schweizer; Dino Di Carlo, ACS Nano, 2015

Intra- and extracellular signaling play critical roles in cell polarity, ultimately leading to the development of functional cell–cell connections, tissues, and organs. In the brain, pathologically oriented neurons are often the cause for disordered circuits, severely impacting motor function, ...

more

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

01-Apr-2015 | Michael A. Brodney; Elizabeth M. Beck; Christopher R. Butler; Gabriela Barreiro; Eric F. Johnson; David Riddell; Kev ..., Journal of Medicinal Chemistry, 2015

In recent years, the first generation of β-secretase (BACE1) inhibitors advanced into clinical development for the treatment of Alzheimer’s disease (AD). However, the alignment of drug-like properties and selectivity remains a major challenge. Herein, we describe the discovery of a novel class of ...

more

Essential genome of Pseudomonas aeruginosa in cystic fibrosis sputum [Microbiology]

31-Mar-2015 | Keith H. Turner; Aimee K. Wessel; Gregory C. Palmer; Justine L. Murray; Marvin Whiteley, Proceedings of the National Academy of Sciences current issue, 2015

Defining the essential genome of bacterial pathogens is central to developing an understanding of the biological processes controlling disease. This has proven elusive for Pseudomonas aeruginosa during chronic infection of the cystic fibrosis (CF) lung. In this paper, using a Monte Carlo ...

more

Page 1 From 76
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE