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1,233 Newest Publications in journal of cellular biochemistry
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Activated EGFR stimulates MUC1 expression in human uterine and pancreatic cancer cell lines
18-05-2013 | Neeraja Dharmaraj, Brian J. Engel, Daniel D. Carson, Journal of Cellular Biochemistry, 2013
Abstract MUC1 is a large cell surface mucin glycoprotein that plays diverse roles in both normal and tumor cell biology. These roles include mucosal hydration and protection, inhibition of embryo implantation, protection of tumor cells from the immune system and reduction of cytotoxic ...
Journal of Cellular Biochemistry: Volume 114, Number 7, July, 2013
10-05-2013 | Journal of Cellular Biochemistry, 2013
Abstract Cover: Immunofluorescence images of MIA PaCa‐2 cells cultured in SCM and SFM. See article by Bose et al., pages 1642–1652. Cover designed by Lucía Sagredo S´nchez.
Estrogen receptor alpha: Molecular mechanisms and emerging insights
03-05-2013 | Nicholes R. Candelaria, Ka Liu, Chin‐Yo Lin, Journal of Cellular Biochemistry, 2013
Abstract Estrogen receptor alpha (ERα) is a cellular receptor for the female sex hormone estrogen and other natural and synthetic ligands and play critical roles in normal development and physiology and in the etiology and treatment of endocrine‐related diseases. ERα is a member of the ...
Concerted expression of the thermogenic and bioenergetic mitochondrial protein machinery in brown adipose tissue
20-04-2013 | Carlos Guillen, Alberto Bartolome, Rocio Vila‐Bedmar, Ana García‐Aguilar, Almudena Gomez‐Hernandez, Manuel Benito, Journal of Cellular Biochemistry, 2013
Abstract Brown adipose tissue (BAT) is specialized in non‐shivering thermogenesis through the expression of the mitochondrial uncoupling protein‐1 (UCP1). In this paper, we describe the relationship between UCP1 and proteins involved in ATP synthesis. By the use of BATIRKO mice, which ...
Metabolic stability of 3‐epi‐1α,25‐dihydroxyvitamin D3 over its parent, 1α,25‐dihydroxyvitamin D3: Comparative metabolism and molecular docking studies using rat CYP24A1
20-04-2013 | Steve Y. Rhieu, Andrew J. Annalora, Guochun Wang, Caroline C. Flarakos, Rose M. Gathungu, Paul Vouros, Rita Sigüeiro ..., Journal of Cellular Biochemistry, 2013
Abstract 3‐epi‐1α,25‐dihydroxyvitamin D3 (3‐epi‐1α,25(OH)2D3), a natural metabolite of 1α,25‐dihydroxyvitamin D3 (1α,25(OH)2D3), exhibits potent vitamin D receptor (VDR)‐mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion. These ...
The Leading Role of Microtubules in Endothelial Barrier Dysfunction: Disassembly of Peripheral Microtubules Leaves Behind the Cytoskeletal Reorganization
20-04-2013 | Irina B. Alieva, Evgeny A. Zemskov, Ksenija M. Smurova, Irina N. Kaverina, Alexander D. Verin, Journal of Cellular Biochemistry, 2013
Abstract Disturbance of the endothelial barrier is characterized by dramatic cytoskeleton reorganization, activation of actomyosin contraction and, finally, leads to intercellular gap formation. Here we demonstrate that the edemagenic agent, thrombin, causes a rapid increase in the human ...
MiR‐125b regulates side population in breast cancer and confers a chemoresistant phenotype
20-04-2013 | Hong‐Jiang Wang, Ying‐Qiu Guo, Guang Tan, Lei Dong, Lei Cheng, Ke‐Jun Li, Zhong‐Yu Wang, Hai‐Feng Luo, Journal of Cellular Biochemistry, 2013
Abstract Resistance to chemotherapy is a major obstacle for the effective treatment of breast cancer and is partially due to the presence of drug resistant stem cell‐like side population (SP). Previous studies have shown elevated miR‐125b is associated with chemoresistance and ...
Helicobacter pylori activates NF‐κB by inducing Ubc13‐mediated ubiquitination of lysine 158 of TAK1
19-04-2013 | Acacia Lamb, JinJing Chen, Steven R. Blanke, Lin‐Feng Chen, Journal of Cellular Biochemistry, 2013
Abstract The Helicobacter pylori virulence factor CagA targets a variety of host proteins to alter different cellular responses, including the induction of pro‐inflammatory cytokines. We have previously shown that CagA‐facilitated lysine 63‐linked ubiquitination of TAK1 is essential for ...
SWI/SNF in cardiac progenitor cell differentiation
19-04-2013 | Ienglam Lei, Liu Liu, Mai Har Sham, Zhong Wang, Journal of Cellular Biochemistry, 2013
Abstract Cardiogenesis requires proper specification, proliferation, and differentiation of cardiac progenitor cells (CPCs). The differentiation of CPCs to specific cardiac cell types is likely guided by a comprehensive network comprised of cardiac transcription factors and epigenetic ...
Cross‐talk between activated monocytes and smooth muscle cells activates the STAT3 pathway and induces resistin and reactive oxygen species production
19-04-2013 | Ana Maria Gan, Monica Madalina Pirvulescu, Daniela Stan, Viorel Simion, Manuela Calin, Ileana Manduteanu, Elena Butoi, Journal of Cellular Biochemistry, 2013
Abstract During the early phase of atherosclerosis, monocytes attach to and migrate through the vessel wall where they activate and communicate with smooth muscle cells (SMC) affecting plaque progression by largely unknown mechanisms. Activation of STAT3 transcription factor is suggested ...
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