25-11-2012 | Ruma Kumari, Richa Saxena, Sameer Tiwari, Dinesh K. Tripathi, Kishore K. Srivastava, Molecular and Cellular Biochemistry, 2012

The mycobacterial FASII multi-enzyme complex has been identified to be a target of Ser/Thr protein kinases (STPKs) of Mycobacterium tuberculosis (MTB), with substrates, including the malonyl-CoA:ACP transacylase (FabD) and the β-ketoacyl-ACP synthases KasA and KasB. These proteins are ...

more

25-11-2012 | C. C. Han, J. W. Wang, Z. X. Pan, H. Tang, S. X. Xiang, J. Wang, L. Li, F. Xu, S. H. Wei, Molecular and Cellular Biochemistry, 2012

To investigate how cholesterol induces hepatocytic steatosis, we investigated the effect of cholesterol on hepatic lipogenesis and the assembly and secretion of very-low-density lipoprotein–triglycerides (VLDL–TGs) in goose primary hepatocytes. We found that cholesterol at 20 μg/ml increased ...

more

25-11-2012 | Nazila Azordegan, Virginia Fraser, Khuong Le, Lyn M. Hillyer, David W. L. Ma, Gabor Fischer, Mohammed H. Moghadasian, Molecular and Cellular Biochemistry, 2012

Cancerogenesis is associated with cell membrane changes. The aim of this study was to investigate whether breast tissues with different degrees of cancer involvement have different fatty acid profiles. Fourteen breast cancer patients with a mean age of 61 years were recruited. Morphological ...

more

25-11-2012 | Philip G. Wong, David W. J. Armstrong, M. Yat Tse, Emily P. A. Brander, Stephen C. Pang, Molecular and Cellular Biochemistry, 2012

Sex-specific differences in hormone-mediated gene regulation may influence susceptibility to cardiac hypertrophy, a primary risk factor for cardiovascular disease. Under hormonal influence, natriuretic peptide (NP) and nitric oxide synthase (NOS) systems modulate cardio-protective gene ...

more

25-11-2012 | Min You, Niramol Savaraj, Macus T. Kuo, Medhi Wangpaichitr, Javier Varona-Santos, Chunjing Wu, Dao M. Nguyen, Lynn Feun, Molecular and Cellular Biochemistry, 2012

Arginine deprivation is a promising strategy for treating ASS-negative malignant tumors including melanoma. However, autophagy can potentially counteract the effectiveness of this treatment by acting as a pro-survival pathway. By combining tumor necrosis factor-related apoptosis-inducing ...

more

25-11-2012 | Daniela Zanini, Roberta Schmatz, Luana Paula Pelinson, Victor Camera Pimentel, Pauline da Costa, Andréia Machado Car ..., Molecular and Cellular Biochemistry, 2012

We aimed to examine the nucleoside triphosphate diphosphohydrolases (NTPDase) in lymphocytes; adenosine deaminase (ADA) and butyrylcholinesterase (BChE) in serum; and acetylcholinesterase (AChE), superoxide dismutase (SOD), and catalase (CAT) activity in whole blood; since these enzymes are ...

more

19-11-2012 | Di Wu, Dechao Song, Xinyun Li, Mei Yu, Changchun Li, Shuhong Zhao, Molecular and Cellular Biochemistry, 2012

Homeobox A10 (HOXA10), a well-known transcriptional factor that can be regulated by estrogen (E2) and progesterone (P4), is necessary not only for endometrial differentiation but also for establishing the conditions required for implantation. However, little research has focused on the ...

more

19-11-2012 | Takashi Shimizu, Eri Imamura, Fumie Magata, Chiaki Murayama, Akio Miyamoto, Molecular and Cellular Biochemistry, 2012

Interleukin 8 (IL-8) is a chemoattractant associated with ovulation in the mammalian ovary. This chemokine is also involved in the recruitment and activation of neutrophils. Using bovine tissue, we examined the possible role of IL-8 in steroid production by theca cells of the large ovarian ...

more

19-11-2012 | Sana Venkata Vijaya Lakshmi, Shaik Mohammad Naushad, Cheruku Apoorva Reddy, Kankanala Saumya, Damera Seshagiri Rao, ..., Molecular and Cellular Biochemistry, 2012

The association between oxidative stress and coronary artery disease (CAD) is well documented. However, the role of epigenetic factors contributing to oxidative stress is relatively unexplored. In this study, we aimed to explore the impact of DNA methylation profile in BCL2/E1B adenovirus ...

more

19-11-2012 | Yejing Zhu, Jinyu Chi, Yue Liu, Yihua Sun, Yu Fu, Xiaohui Zhang, Xueliang Ding, Xinhua Yin, Dechao Zhao, Molecular and Cellular Biochemistry, 2012

Cyclosporine (CsA) has become a mainstay for immune suppression of organ transplants. It is known that patients receiving CsA manifest increased growth of aggressive cardiotoxicity. We have demonstrated that CsA induces myocardium cell apoptosis in vivo and vitro. Recently, dishevelled-1 ...

more