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258 Newest Publications in organic lettersrss
17-11-2014 | G. Gangadhararao; Anasuyamma Uruvakilli; K. C. Kumara Swamy, Organic Letters, 2014
Copper-catalyzed oxidative ring-expansion/intramolecular electrophilic substitution of 3-dienylindoles leading to cyclopenta[c]quinolines and 3-indenylindoles under aerobic conditions is described. The precursors, 3-dienylindoles, are formed via Friedel–Crafts alkenylation followed by ...
14-11-2014 | Yuewei Zhang; Fengzhi Yang; Lianyou Zheng; Qun Dang; Xu Bai, Organic Letters, 2014
Organic Letters DOI: 10.1021/ol502971e
05-11-2014 | Graham W. Heberlig; Monica Wirz; Meng Wang; Christopher N. Boddy, Organic Letters, 2014
Zearalenone and radicicol are highly related resorcylic acid lactones with the rare property of having opposite stereochemical configurations of the secondary alcohol involved in lactone formation. The ability of the thioesterases from the zearalenone and radicicol biosynthetic pathways to ...
03-11-2014 | John Y. L. Chung; Yong-Li Zhong; Kevin M. Maloney; Robert A. Reamer; Jeffrey C. Moore; Hallena Strotman; Alexei Kali ..., Organic Letters, 2014
An asymmetric synthesis of dual orexin receptor antagonist MK-6096 (1) is described. Key steps for the trans-2,5-disubstituted piperidinyl ether fragment include a biocatalytic transamination, a trans-selective Mukaiyama aldol, and a regioselective pyridyl SNAr process. The pyrimidyl benzoic acid ...
30-10-2014 | Chicco Manzuna Sapu; Tamás Görbe; Richard Lihammar; Jan-E. Bäckvall; Jan Deska, Organic Letters, 2014
A novel migratory dynamic kinetic resolution based on the interplay between an enzyme acylation catalyst and a heterogeneous Brønsted acid as an isomerization/racemization catalyst gives rise to carbocyclic allylic esters with excellent stereoselectivity from readily available tertiary carbinols. ...
30-10-2014 | Rina Suzuki; Raku Irie; Yanit Harntaweesup; Kazuo Tachibana; Patrick T. Holland; D. Tim Harwood; Feng Shi; Veronica ..., Organic Letters, 2014
The isolation and structural determination of new marine ladder-frame polyethers, brevisulcatic acids-1 (1) and -4 (2) are reported. Brevisulcatic acids were isolated from the dinoflagellate Karenia brevisulcata, which was identified as the causative species of a major red tide event in New ...
28-10-2014 | Benjamin A. Chalmers; Subham Saha; Tri Nguyen; John McMurtrie; Snorri Th. Sigurdsson; Steven E. Bottle; Kye-Simeon M ..., Organic Letters, 2014
We report the synthesis of a new class of molecules which are hybrids of long-lived tetramethylisoindolinoxyl (TMIO) radicals and the pyrido[1,2-a]benzimidazole (PyrImid) scaffold. These compounds represent a new lead for noncovalently binding nucleic acid probes, as they interact with nucleic ...
24-10-2014 | Yasunori Mitsuoka; Yuko Fujimura; Reiko Waki; Akira Kugimiya; Tsuyoshi Yamamoto; Yoshiyuki Hari; Satoshi Obika, Organic Letters, 2014
Organic Letters DOI: 10.1021/ol503029v
24-10-2014 | Xue-Jing Quan; Zhi-Hui Ren; Yao-Yu Wang; Zheng-Hui Guan, Organic Letters, 2014
Organic Letters DOI: 10.1021/ol5027975
21-10-2014 | Zhuye Liang; Weichao Xue; Kunhua Lin; Hegui Gong, Organic Letters, 2014
Organic Letters DOI: 10.1021/ol502682q