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282 Newest Publications in organic lettersrss
05-Mar-2015 | Shotaro Hoshino; Toshiyuki Wakimoto; Hiroyasu Onaka; Ikuro Abe, Organic Letters, 2015
The soil-derived bacterium, Streptomyces sp. CJ-5, was cocultured with the mycolic acid-containing bacterium Tsukamurella pulmonis TP-B0596. The combined culture method significantly enhanced the production of the secondary metabolites in Streptomyces sp. CJ-5, leading to the isolation of three ...
27-Feb-2015 | Prabhakar Ramchandra Joshi; Sridhar Undeela; Doni Dhanoj Reddy; Kiran Kumar Singarapu; Rajeev S. Menon, Organic Letters, 2015
Facile conversion of α,β-unsaturated aldehydes and ketones into highly substituted arenes via a base-mediated, completely regioselective, air-oxidative [3 + 3] benzannulation reaction with readily available 4-sulfonylcrotonates or 1,3-bisphenylsulfonylpropene is reported. The reaction can also be ...
23-Feb-2015 | Kyungho Park; Sunwoo Lee, Organic Letters, 2015
Organic Letters DOI: 10.1021/acs.orglett.5b00303
20-Feb-2015 | Scott W. Krabbe; Jeffrey S. Johnson, Organic Letters, 2015
The asymmetric total syntheses of the α-benzylidene-γ-butyrolactone natural products megacerotonic acid and shimobashiric acid A have been accomplished in nine and 11 steps, respectively, from simple, commercially available starting materials. The key step for each synthesis is the ...
16-Feb-2015 | Melinda Nonn; Loránd Kiss; Matti Haukka; Santos Fustero; Ferenc Fülöp, Organic Letters, 2015
The selective introduction of fluorine onto the skeleton of an aminocyclopentane or cyclohexane carboxylate has been developed through a novel and efficient fluoride opening of an activated aziridine ring with XtalFluor-E. The reaction proceeded through a stereoselective aziridination of the ...
11-Feb-2015 | Lucy R. Peacock; Robert S. L. Chapman; Adam C. Sedgwick; Mary F. Mahon; Dominique Amans; Steven D. Bull, Organic Letters, 2015
Aryl-aldehydes containing ortho-substituted α,β-unsaturated carboxylic acid derivatives react with hydroxylamine to afford reactive N-hydroxy-carbinolamine intermediates that undergo intramolecular aza-conjugate addition reactions to afford isoindole nitrones and 3,4-dihydroisoquinoline nitrones ...
10-Feb-2015 | Eduard R. Rakhmankulov; Konstantin L. Ivanov; Ekaterina M. Budynina; Olga A. Ivanova; Alexey O. Chagarovskiy; Dmitri ..., Organic Letters, 2015
Organic Letters DOI: 10.1021/ol5037562
09-Feb-2015 | Charles E. Ocampo; Doris Lee; Timothy F. Jamison, Organic Letters, 2015
Organic Letters DOI: 10.1021/ol503612h
28-Jan-2015 | Alan R. Healy; Francesco Vinale; Matteo Lorito; Nicholas J. Westwood, Organic Letters, 2015
The bioactive natural product harzianic acid was prepared for the first time in just six steps (longest linear sequence) with an overall yield of 22%. The identification of conditions to telescope amide bond formation and a Lacey–Dieckmann reaction into one pot proved important. The three ...
26-Jan-2015 | Chun Gui; Qinglian Li; Xuhua Mo; Xiangjing Qin; Junying Ma; Jianhua Ju, Organic Letters, 2015
Bioinformatic analyses indicate that TrdC, SlgL, LipX2, KirHI, and FacHI belong to a group of highly homologous proteins involved in biosynthesis of actinomycete-derived tirandamycin B, streptolydigin, α-lipomycin, kirromycin, and factumycin, respectively. However, assignment of their ...