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8,586 Newest Publications in organic letters

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Asymmetric Hydrogenation of α-Purine Nucleobase-Substituted Acrylates with Rhodium Diphosphine Complexes: Access to Tenofovir Analogues

26-Apr-2016 | Huan-Li Sun; Fei Chen; Ming-Sheng Xie; Hai-Ming Guo; Gui-Rong Qu; Yan-Mei He; Qing-Hua Fan, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b00869

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Development and Applications of Transesterification Reactions Catalyzed by N-Heterocyclic Olefins

26-Apr-2016 | Marcus Blümel; Janina-Miriam Noy; Dieter Enders; Martina H. Stenzel; Thanh V. Nguyen, Organic Letters, 2016

A novel method to utilize N-heterocyclic olefins (NHOs), the alkylidene derivatives of N-heterocycic carbenes, as organocatalysts to promote transesterification reactions has been developed. Because of their strong Brønsted/Lewis basicity, NHOs can enhance the nucleophilicity of alcohols for ...

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Enantioselective Total Synthesis of (+)-Amphirionin-4

26-Apr-2016 | Arun K. Ghosh; Prasanth R. Nyalapatla, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b00942

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A Three-Step Synthesis of Tetrasubstituted NH-Pyrroles

26-Apr-2016 | Tristan A. Reekie; Etienne J. Donckele; Giorgio Manenti; Salome Püntener; Nils Trapp; François Diederich, Organic Letters, 2016

Buta-1,3-dienes appended with electron-withdrawing groups (EWGs), derived from the [2 + 2] cycloaddition–retroelectrocyclization (CA–RE) cascade, react with (predominately) nitrogen-based nucleophiles affording tetrasubstituted 2-amino-NH-pyrroles in moderate to excellent yields with complete ...

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Asymmetric Hydrogenation of α-Substituted Acrylic Acids Catalyzed by a Ruthenocenyl Phosphino-oxazoline–Ruthenium Complex

25-Apr-2016 | Jing Li; Jiefeng Shen; Chao Xia; Yanzhao Wang; Delong Liu; Wanbin Zhang, Organic Letters, 2016

Asymmetric hydrogenation of various α-substituted acrylic acids was carried out using RuPHOX–Ru as a chiral catalyst under 5 bar H2, affording the corresponding chiral α-substituted propanic acids in up to 99% yield and 99.9% ee. The reaction could be performed on a gram-scale with a relatively ...

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Synthesis of Acyl Terphenyls and Higher Polyaromatics via Base-Promoted C–H Functionalization of Acetylarenes with Arylacetylenes

25-Apr-2016 | Elena Yu. Schmidt; Elena V. Ivanova; Inna V. Tatarinova; Igor’ A. Ushakov; Nadezhda V. Semenova; Alexander V. Vashch ..., Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b00782

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Total Synthesis of the Proposed Structure of Marineosin A

25-Apr-2016 | Bing Xu; Guang Li; Jing Li; Yian Shi, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b00632

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Synthesis of (−)-Piperitylmagnolol Featuring ortho-Selective Deiodination and Pd-Catalyzed Allylation

25-Apr-2016 | Atsushi Ikoma; Narihito Ogawa; Daiki Kondo; Hiroki Kawada; Yuichi Kobayashi, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b00706

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A Comparative Investigation: Group 9 Cp*M(III)-Catalyzed Formal [4 + 2] Cycloaddition as an Atom-Economic Approach to Quinazolines

25-Apr-2016 | Xiaoming Wang; Andreas Lerchen; Frank Glorius, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b00716

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