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9,044 Newest Publications in organic letters

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Direct Synthesis of Polyaryls by Consecutive Oxidative Cross-Coupling of Phenols with Arenes

16-Aug-2016 | Alina Dyadyuk; Kavitha Sudheendran; Yulia Vainer; Vlada Vershinin; Alexander I. Shames; Doron Pappo, Organic Letters, 2016

A bioinspired iron-catalyzed consecutive oxidative cross-coupling reaction between a single phenolic unit and nucleophilic arenes was developed. This sustainable transformation offers a selective synthetic strategy for the preparation of complex polyaryl compounds directly from readily available ...

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Isolation and Identification of Intermediates of the Oxidative Bilirubin Degradation

16-Aug-2016 | Marcel Ritter; Raphael A. Seidel; Peter Bellstedt; Bernd Schneider; Michael Bauer; Helmar Görls; Georg Pohnert, Organic Letters, 2016

Four endogenous products of oxidative bilirubin degradation were isolated and fully characterized. The constitutional isomers belong to the propentdyopents (PDPs). Their structures and further oxidative transformations to biologically active bilirubin oxidation end products (Z-BOXes) are ...

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Protecting-Group-Free Total Synthesis of (−)-Lycopodine via Phosphoric Acid Promoted Alkyne Aza-Prins Cyclization

16-Aug-2016 | Donghui Ma; Zhuliang Zhong; Zaimin Liu; Mingjie Zhang; Shiyan Xu; Dengyu Xu; Dengpeng Song; Xingang Xie; Xuegong She, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b02072

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Visible-Light Photocatalytic Aerobic Annulation for the Green Synthesis of Pyrazoles

16-Aug-2016 | Ya Ding; Te Zhang; Qiu-Yun Chen; Chunyin Zhu, Organic Letters, 2016

A selective and high yielding synthesis of polysubstituted pyrazoles through a VLPC (visible light photoredox catalysis)-promoted reaction of hydrazine with Michael acceptors is reported. The method employs very mild reaction conditions and uses air as the terminal oxidant, which makes the ...

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Enantioselective Intermolecular Cyclopropanations for the Synthesis of Chiral Pyrimidine Carbocyclic Nucleosides

16-Aug-2016 | Ming-Sheng Xie; Peng Zhou; Hong-Ying Niu; Gui-Rong Qu; Hai-Ming Guo, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b02104

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Solvent-Controlled, Tunable Hydrosulfonylation of 3-Cyclopropylideneprop-2-en-1-ones

16-Aug-2016 | Maozhong Miao; Yi Luo; Huaping Xu; Zhengkai Chen; Jianfeng Xu; Hongjun Ren, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b02047

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Gold-Catalyzed Direct Assembly of Aryl-Annulated Carbazoles from 2-Alkynyl Arylazides and Alkynes

16-Aug-2016 | Nan Li; Xiao-Lei Lian; Yu-Hui Li; Tian-Yi Wang; Zhi-Yong Han; Liming Zhang; Liu-Zhu Gong, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01627

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Mild Synthesis of Sterically Congested Alkyl Aryl Ethers

16-Aug-2016 | Erik Lindstedt; Elin Stridfeldt; Berit Olofsson, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01975

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Collective Synthesis of Phenanthridinone through C–H Activation Involving a Pd-Catalyzed Aryne Multicomponent Reaction

16-Aug-2016 | Minghao Feng; Bingqing Tang; Hong-Xi Xu; Xuefeng Jiang, Organic Letters, 2016

A palladium-catalyzed multicomponent reaction (MCR) involving aryne, CO, and aniline is established for straightforward assembly of a phenanthridinone scaffold through C–H bond activation. Free combination with multiple kinds of readily available anilines and arynes is facilely achieved for ...

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Ru(II)/Organo Relay Catalytic Three-Component Reaction of 3-Diazooxindoles, Amines, and Nitroalkene: Formal Synthesis of (−)-Psychotrimine

16-Aug-2016 | Xiao-Lei Lian; Jing Meng; Zhi-Yong Han, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b02019

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