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8,813 Newest Publications in organic letters


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Detrifluoroacetylative in Situ Generation of Free 3-Fluoroindolin-2-one-Derived Tertiary Enolates: Design, Synthesis, and Assessment of Reactivity toward Asymmetric Mannich Reactions

15-Jun-2016 | Chen Xie; Lijun Zhang; Wanxing Sha; Vadim A. Soloshonok; Jianlin Han; Yi Pan, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01516


Oxidative Radical Addition–Cyclization of Sulfonyl Hydrazones with Simple Olefins by Binary Acid Catalysis

15-Jun-2016 | Xingren Zhong; Jian Lv; Sanzhong Luo, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01360


Synthesis and Photophysical Properties of Fluorescence Molecular Probe for Turn-ON-Type Detection of Cytosine Bulge DNA

14-Jun-2016 | Rajiv Kumar Verma; Fumie Takei; Kazuhiko Nakatani, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01378


Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines

14-Jun-2016 | Ahmed Chelouan; Rocío Recio; Lorenzo G. Borrego; Eleuterio Álvarez; Noureddine Khiar; Inmaculada Fernández, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01509


Ruthenium-Catalyzed Dehydrogenative β-Benzylation of 1,2,3,4-Tetrahydroquinolines with Aryl Aldehydes: Access to Functionalized Quinolines

14-Jun-2016 | Zhenda Tan; Huanfeng Jiang; Min Zhang, Organic Letters, 2016

A new benzylation protocol, enabling straightforward access to β-benzylated quinolines, has been demonstrated. By employing readily available [RuCl2(p-cymene)]2 as a catalyst and O2 as a sole green oxidant, various 1,2,3,4-tetrahydroquinolines were efficiently converted in combination with aryl ...


Copper-Catalyzed Direct Propargylation of Polyfluoroarenes with Secondary Propargyl Phosphates

14-Jun-2016 | Yan-Bo Yu; Zhi-Ji Luo; Xingang Zhang, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01642


Synthesis of the C9–C25 Subunit of Spirastrellolide B

14-Jun-2016 | Soma Maitra; Mahipal Bodugam; Salim Javed; Paul R. Hanson, Organic Letters, 2016

The synthesis of the C9–C25 subunit of the marine natural product spirastrellolide B is reported. The key synthetic features included the union of the two key fragments 5 and 6 via a Suzuki–Miyaura coupling reaction and a late-stage, one-pot sequential deprotection/cascade Achmatowicz ...


Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides

13-Jun-2016 | Wen-Xue Huang; Lian-Jin Liu; Bo Wu; Guang-Shou Feng; Baomin Wang; Yong-Gui Zhou, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01190


Synthesis of Quaternary 3,3-Disubstituted 2-Oxindoles from 2-Substituted Indole Using Selectfluor

13-Jun-2016 | Xiaojian Jiang; Junjie Yang; Feng Zhang; Pei Yu; Peng Yi; Yewei Sun; Yuqiang Wang, Organic Letters, 2016

Organic Letters DOI: 10.1021/acs.orglett.6b01367


Stereoselection in Intramolecular Diels–Alder Reactions of 2-Cyano-1-azadienes: Indolizidine and Quinolizidine Synthesis

13-Jun-2016 | Gidget C. Tay; Nicholas Sizemore; Scott D. Rychnovsky, Organic Letters, 2016

Progress toward understanding the scope and diastereoselectivity of intramolecular Diels–Alder reactions using 2-cyano-1-azadienes is described herein. The resulting cyanoenamine products are underutilized intermediates in organic synthesis. Assembly of the Diels–Alder precursors was achieved ...


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