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10,439 Newest Publications in organic letters


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Domino Aza-Michael-ih-Diels–Alder Reaction to Various 3-Vinyl-1,2,4-triazines: Access to Polysubstituted Tetrahydro-1,6-naphthyridines

31-Aug-2017 | Jabrane Jouha; Floris Buttard; Magali Lorion; Clément Berthonneau; Mostafa Khouili; Marie-Aude Hiebel; Gérald Guilla ..., Organic Letters, 2017

Organic Letters DOI: 10.1021/acs.orglett.7b02132


Iridium-Catalyzed Asymmetric Hydrogenation of 2H-Chromenes: A Highly Enantioselective Approach to Isoflavan Derivatives

31-Aug-2017 | Jingzhao Xia; Yu Nie; Guoqiang Yang; Yangang Liu; Wanbin Zhang, Organic Letters, 2017

Organic Letters DOI: 10.1021/acs.orglett.7b02341


Copper-Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amides

31-Aug-2017 | Subhadip De; Junli Yin; Dawei Ma, Organic Letters, 2017

Organic Letters DOI: 10.1021/acs.orglett.7b02326


Scalable Synthesis of a Key Intermediate for the Production of Pleuromutilin-Based Antibiotics

31-Aug-2017 | Stephen K. Murphy; Mingshuo Zeng; Seth B. Herzon, Organic Letters, 2017

Organic Letters DOI: 10.1021/acs.orglett.7b02476


Useful Applications of Enantioselective (4 + 2)-Cycloaddition Reactions to the Synthesis of Chiral 1,2-Amino Alcohols, 1,2-Diamines, and β-Amino Acids

31-Aug-2017 | Karla Mahender Reddy; Barla Thirupathi; E. J. Corey, Organic Letters, 2017

The scope of enantioselective (4 + 2)-cycloaddition reactions has been expanded to include reactive olefinic components that are equivalents of three inoperable and unstable ethylene derivatives: 1-hydroxy-2-aminoethylene, 1,2-diaminoethylene, and β-aminoacrylic acid. In this way, a variety of ...


Synthesis of Spirobidihydropyrazole through Double 1,3-Dipolar Cycloaddition of Nitrilimines with Allenoates

31-Aug-2017 | Honglei Liu; Hao Jia; Bo Wang; Yumei Xiao; Hongchao Guo, Organic Letters, 2017

Organic Letters DOI: 10.1021/acs.orglett.7b01961


Cnidimonins A–C, Three Types of Hybrid Dimer from Cnidium monnieri: Structural Elucidation and Semisynthesis

31-Aug-2017 | Fangyi Su; Zheng Zhao; Shuanggang Ma; Rubing Wang; Yong Li; Yunbao Liu; Yuhuan Li; Li Li; Jing Qu; Shishan Yu, Organic Letters, 2017

Three pairs of racemic dimers, (±)-cnidimonins A–C (1–3), were isolated from the fruits of Cnidium monnieri. They represent novel hybrid-dimerization patterns of coumarin skeleton with structurally diverse units (flavonol, benzofuran, and chromone) via an unprecedented terminal chiral carbon of ...


Direct Access to 2,3,4,6-Tetrasubstituted Tetrahydro-2H-pyrans via Tandem SN2′–Prins Cyclization

31-Aug-2017 | Jimena Scoccia; Sixto J. Pérez; Victoria Sinka; Daniel A. Cruz; Juan M. López-Soria; Israel Fernández; Víctor S. Mar ..., Organic Letters, 2017

Organic Letters DOI: 10.1021/acs.orglett.7b02270


Catalytic Reductions and Tandem Reactions of Nitro Compounds Using in Situ Prepared Nickel Boride Catalyst in Nanocellulose Solution

31-Aug-2017 | Kaniraj Jeya Prathap; Qiong Wu; Richard T. Olsson; Peter Dinér, Organic Letters, 2017

A mild and efficient method for the in situ reduction of a wide range of nitroarenes and aliphatic nitrocompounds to amines in excellent yields using nickel chloride/sodium borohydride in a solution of TEMPO-oxidized nanocellulose in water (0.01 wt %) is described. The nanocellulose has a ...


Copper- or Nickel-Enabled Oxidative Cross-Coupling of Unreactive C(sp3)–H Bonds with Azole C(sp2)–H Bonds: Rapid Access to β-Azolyl Propanoic Acid Derivatives

30-Aug-2017 | Guangying Tan; Luoqiang Zhang; Xingrong Liao; Yang Shi; Yimin Wu; Yudong Yang; Jingsong You, Organic Letters, 2017

Organic Letters DOI: 10.1021/acs.orglett.7b02265


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