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10,158 Newest Publications in proceedings of the national academy of sciences current issue
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matching the following criteria
Evidence of a liquid-liquid phase transition in hot dense hydrogen [Physics]
14-05-2013 | Vasily Dzyabura; Mohamed Zaghoo; Isaac F. Silvera, Proceedings of the National Academy of Sciences current issue, 2013
We use pulsed-laser heating of hydrogen at static pressures in the megabar pressure region to search for the plasma phase transition to liquid atomic metallic hydrogen. We heat our samples substantially above the melting line and observe a plateau in a temperature vs. laser power curve that ...
Latency of Epstein-Barr virus is disrupted by gain-of-function mutant cellular AP-1 proteins that preferentially bind methylated DNA [Medical Sciences]
14-05-2013 | Kuan-Ping Yu; Lee Heston; Richard Park; Zhaowei Ding; Ruth Wang’ondu; Henri-Jacques Delecluse; George Miller, Proceedings of the National Academy of Sciences current issue, 2013
ZEBReplication Activator (ZEBRA), a viral basic zipper protein that initiates the Epstein–Barr viral lytic cycle, binds to DNA and activates transcription through heptamer ZEBRA response elements (ZREs) related to AP-1 sites. A component of the biologic action of ZEBRA is attributable to ...
Arabidopsis nanodomain-delimited ABA signaling pathway regulates the anion channel SLAH3 [Plant Biology]
14-05-2013 | Fatih Demir; Claudia Horntrich; Jörg O. Blachutzik; Sönke Scherzer; Yvonne Reinders; Sylwia Kierszniowska; Waltraud ..., Proceedings of the National Academy of Sciences current issue, 2013
The phytohormone abscisic acid (ABA) plays a key role in the plant response to drought stress. Hence, ABA-dependent gene transcription and ion transport is regulated by a variety of protein kinases and phosphatases. However, the nature of the membrane-delimited ABA signal transduction steps ...
AMPA receptor exchange underlies transient memory destabilization on retrieval [Neuroscience]
14-05-2013 | Ingie Hong; Jeongyeon Kim; Jihye Kim; Sukwon Lee; Hyoung-Gon Ko; Karim Nader; Bong-Kiun Kaang; Richard W. Tsien; Suk ..., Proceedings of the National Academy of Sciences current issue, 2013
A consolidated memory can be transiently destabilized by memory retrieval, after which memories are reconsolidated within a few hours; however, the molecular substrates underlying this destabilization process remain essentially unknown. Here we show that at lateral amygdala synapses, fear ...
Smoke-derived karrikin perception by the {alpha}/{beta}-hydrolase KAI2 from Arabidopsis [Plant Biology]
14-05-2013 | Yongxia Guo; Zuyu Zheng; James J. La Clair; Joanne Chory; Joseph P. Noel, Proceedings of the National Academy of Sciences current issue, 2013
Genetic studies in Arabidopsis implicate an α/β-hydrolase, KARRIKIN-INSENSITIVE 2 (KAI2) as a receptor for karrikins, germination-promoting butenolide small molecules found in the smoke of burned plants. However, direct biochemical evidence for the interaction between KAI2 and karrikin and ...
Weather and anomalous heat flow occurring near absolute zero [Physics]
14-05-2013 | Joseph J. Niemela, Proceedings of the National Academy of Sciences current issue, 2013
It usually takes some work to make heat flow from a colder body to a hotter one. In PNAS, Urban et al. (1) have carefully observed precisely this process in a sample space partially filled with liquid helium initially in near equilibrium with its saturated vapor; specifically, a complex heat...
IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner [Immunology]
14-05-2013 | Rebecca Berlant Liu; Boris Engels; Karin Schreiber; Cezary Ciszewski; Andrea Schietinger; Hans Schreiber; Bana Jabri, Proceedings of the National Academy of Sciences current issue, 2013
A major challenge of cancer immunotherapy is the persistence and outgrowth of subpopulations that lose expression of the target antigen. IL-15 is a potent cytokine that can promote organ-specific autoimmunity when up-regulated on tissue cells. Here we report that T cells eradicated 2-wk-old ...
Activation of heme biosynthesis by a small molecule that is toxic to fermenting Staphylococcus aureus [Microbiology]
14-05-2013 | Laura A. Mike; Brendan F. Dutter; Devin L. Stauff; Jessica L. Moore; Nicholas P. Vitko; Olusegun Aranmolate; Thomas ..., Proceedings of the National Academy of Sciences current issue, 2013
Staphylococcus aureus is a significant infectious threat to global public health. Acquisition or synthesis of heme is required for S. aureus to capture energy through respiration, but an excess of this critical cofactor is toxic to bacteria. S. aureus employs the heme sensor system (HssRS) to ...
Fe-carbonyl is a key player in planetary magmas [Earth, Atmospheric, and Planetary Sciences]
14-05-2013 | Marc M. Hirschmann, Proceedings of the National Academy of Sciences current issue, 2013
Introducing Fe-CarbonylAlthough the volatile elements C and H are minor constituents of magmas on terrestrial planets (Earth-like rocky bodies, including Earth, Mercury, Venus, Mars, and the Moon), they play an outsized role in planetary processes, having crucial influence on planetary ...
Degassing of reduced carbon from planetary basalts [Earth, Atmospheric, and Planetary Sciences]
14-05-2013 | Diane T. Wetzel; Malcolm J. Rutherford; Steven D. Jacobsen; Erik H. Hauri; Alberto E. Saal, Proceedings of the National Academy of Sciences current issue, 2013
Degassing of planetary interiors through surface volcanism plays an important role in the evolution of planetary bodies and atmospheres. On Earth, carbon dioxide and water are the primary volatile species in magmas. However, little is known about the speciation and degassing of carbon in ...
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