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17,273 Newest Publications in proceedings of the national academy of sciences current issue

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matching the following criteria

Regulation of oxygen delivery to the body via hypoxic vasodilation [Medical Sciences]

19-May-2015 | Shathiyah Kulandavelu; Wayne Balkan; Joshua M. Hare, Proceedings of the National Academy of Sciences current issue, 2015

The respiratory system has traditionally been thought of as a two-gas model: hemoglobin (Hb) within red blood cells (RBC) binds oxygen in the lungs, delivers the oxygen to peripheral tissues, and binds carbon dioxide, which is returned to the lungs, released, and expired. However, fine-tuning of ...

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Age-related changes in working memory and the ability to ignore distraction [Psychological and Cognitive Sciences]

19-May-2015 | Fiona McNab; Peter Zeidman; Robb B. Rutledge; Peter Smittenaar; Harriet R. Brown; Rick A. Adams; Raymond J. Dolan, Proceedings of the National Academy of Sciences current issue, 2015

A weakened ability to effectively resist distraction is a potential basis for reduced working memory capacity (WMC) associated with healthy aging. Exploiting data from 29,631 users of a smartphone game, we show that, as age increases, working memory (WM) performance is compromised more by ...

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Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair [Biophysics and Computational Biology]

19-May-2015 | Dylan A. Reid; Sarah Keegan; Alejandra Leo-Macias; Go Watanabe; Natasha T. Strande; Howard H. Chang; Betul Akgol Oks ..., Proceedings of the National Academy of Sciences current issue, 2015

Nonhomologous end-joining (NHEJ) is a major repair pathway for DNA double-strand breaks (DSBs), involving synapsis and ligation of the broken strands. We describe the use of in vivo and in vitro single-molecule methods to define the organization and interaction of NHEJ repair proteins at DSB ...

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Rational design of self-assembly pathways for complex multicomponent structures [Chemistry]

19-May-2015 | William M. Jacobs; Aleks Reinhardt; Daan Frenkel, Proceedings of the National Academy of Sciences current issue, 2015

The field of complex self-assembly is moving toward the design of multiparticle structures consisting of thousands of distinct building blocks. To exploit the potential benefits of structures with such “addressable complexity,” we need to understand the factors that optimize the yield and the ...

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The membrane remodeling protein Pex11p activates the GTPase Dnm1p during peroxisomal fission [Cell Biology]

19-May-2015 | Chris Williams; Lukasz Opalinski; Christiane Landgraf; Joseph Costello; Michael Schrader; Arjen M. Krikken; Kèvin Kn ..., Proceedings of the National Academy of Sciences current issue, 2015

The initial phase of peroxisomal fission requires the peroxisomal membrane protein Peroxin 11 (Pex11p), which remodels the membrane, resulting in organelle elongation. Here, we identify an additional function for Pex11p, demonstrating that Pex11p also plays a crucial role in the final step of ...

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Neuronal thresholds and choice-related activity of otolith afferent fibers during heading perception [Neuroscience]

19-May-2015 | Xiong-jie Yu; J. David Dickman; Gregory C. DeAngelis; Dora E. Angelaki, Proceedings of the National Academy of Sciences current issue, 2015

How activity of sensory neurons leads to perceptual decisions remains a challenge to understand. Correlations between choices and single neuron firing rates have been found early in vestibular processing, in the brainstem and cerebellum. To investigate the origins of choice-related activity, we ...

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In-use product stocks link manufactured capital to natural capital [Sustainability Science]

19-May-2015 | Wei-Qiang Chen; T. E. Graedel, Proceedings of the National Academy of Sciences current issue, 2015

In-use stock of a product is the amount of the product in active use. In-use product stocks provide various functions or services on which we rely in our daily work and lives, and the concept of in-use product stock for industrial ecologists is similar to the concept of net manufactured...

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Correction for Sun et al., Nucleation of metastable aragonite CaCO3 in seawater [Correction]

19-May-2015 | Proceedings of the National Academy of Sciences current issue, 2015

APPLIED PHYSICAL SCIENCES Correction for “Nucleation of metastable aragonite CaCO3 in seawater,” by Wenhao Sun, Saivenkataraman Jayaraman, Wei Chen, Kristin A. Persson, and Gerbrand Ceder, which appeared in issue 11, March 17, 2015, of Proc Natl Acad Sci USA (112:3199–3204; first published March ...

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Nonlinearity and chaos in ecological dynamics revisited [Ecology]

19-May-2015 | Ottar N. Bjørnstad, Proceedings of the National Academy of Sciences current issue, 2015

Historically, both experimental and theoretical ecologists have sought to emulate the development of early theory in the physical sciences: the ideal that a few simple equations may accurately predict the complex movement of celestial bodies or interactions among molecules in mixing gasses. In ...

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Correction for Sano et al., Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways [Correction]

19-May-2015 | Proceedings of the National Academy of Sciences current issue, 2015

MEDICAL SCIENCES Correction for “Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways,” by Shigetoshi Sano, Masahiro Kira, Satoshi Takagi, Kunihiko Yoshikawa, Junji Takeda, and Satoshi Itami, which appeared in issue 25, December 5, 2000, of Proc Natl ...

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