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20,410 Newest Publications in proceedings of the national academy of sciences current issue

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matching the following criteria

Impact of adolescent marijuana use on intelligence: Results from two longitudinal twin studies [Psychological and Cognitive Sciences]

02-Feb-2016 | Nicholas J. Jackson; Joshua D. Isen; Rubin Khoddam; Daniel Irons; Catherine Tuvblad; William G. Iacono; Matt McGue; ..., Proceedings of the National Academy of Sciences current issue, 2016

Marijuana is one of the most commonly used drugs in the United States, and use during adolescence—when the brain is still developing—has been proposed as a cause of poorer neurocognitive outcome. Nonetheless, research on this topic is scarce and often shows conflicting results, with some studies ...

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Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers [Genetics]

02-Feb-2016 | Miika Mehine; Eevi Kaasinen; Hanna-Riikka Heinonen; Netta Mäkinen; Kati Kämpjärvi; Nanna Sarvilinna; Mervi Aavikko; ..., Proceedings of the National Academy of Sciences current issue, 2016

Uterine leiomyomas are common benign smooth muscle tumors that impose a major burden on women’s health. Recent sequencing studies have revealed recurrent and mutually exclusive mutations in leiomyomas, suggesting the involvement of molecularly distinct pathways. In this study, we explored ...

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T-cell-intrinsic Tif1{alpha}/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy [Immunology and Inflammation]

02-Feb-2016 | Jimena Perez-Lloret; Isobel S. Okoye; Riccardo Guidi; Yashaswini Kannan; Stephanie M. Coomes; Stephanie Czieso; Gabr ..., Proceedings of the National Academy of Sciences current issue, 2016

There is a paucity of new therapeutic targets to control allergic reactions and forestall the rising trend of allergic diseases. Although a variety of immune cells contribute to allergy, cytokine-secreting αβ+CD4+ T-helper 2 (TH2) cells orchestrate the type-2–driven immune response in a large ...

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Subunit stoichiometry and arrangement in a heteromeric glutamate-gated chloride channel [Physiology]

02-Feb-2016 | Nurit Degani-Katzav; Revital Gortler; Lilach Gorodetzki; Yoav Paas, Proceedings of the National Academy of Sciences current issue, 2016

The invertebrate glutamate-gated chloride-selective receptors (GluClRs) are ion channels serving as targets for ivermectin (IVM), a broad-spectrum anthelmintic drug used to treat human parasitic diseases like river blindness and lymphatic filariasis. The native GluClR is a heteropentamer ...

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Stimulus-induced visual cortical networks are recapitulated by spontaneous local and interareal synchronization [Neuroscience]

02-Feb-2016 | Christopher M. Lewis; Conrado A. Bosman; Thilo Womelsdorf; Pascal Fries, Proceedings of the National Academy of Sciences current issue, 2016

Intrinsic covariation of brain activity has been studied across many levels of brain organization. Between visual areas, neuronal activity covaries primarily among portions with similar retinotopic selectivity. We hypothesized that spontaneous interareal coactivation is subserved by neuronal ...

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The decadal state of the terrestrial carbon cycle: Global retrievals of terrestrial carbon allocation, pools, and residence times [Environmental Sciences]

02-Feb-2016 | A. Anthony Bloom; Jean-François Exbrayat; Ivar R. van der Velde; Liang Feng; Mathew Williams, Proceedings of the National Academy of Sciences current issue, 2016

The terrestrial carbon cycle is currently the least constrained component of the global carbon budget. Large uncertainties stem from a poor understanding of plant carbon allocation, stocks, residence times, and carbon use efficiency. Imposing observational constraints on the terrestrial carbon ...

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Exploring why Costa Rica outperforms the United States in life expectancy: A tale of two inequality gradients [Social Sciences]

02-Feb-2016 | Luis Rosero-Bixby; William H. Dow, Proceedings of the National Academy of Sciences current issue, 2016

Mortality in the United States is 18% higher than in Costa Rica among adult men and 10% higher among middle-aged women, despite the several times higher income and health expenditures of the United States. This comparison simultaneously shows the potential for substantially lowering mortality in ...

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Inner Workings: Building accelerator afterburners with plasma [Inner Workings]

02-Feb-2016 | David J. Harris, Proceedings of the National Academy of Sciences current issue, 2016

Particle colliders are pushing the limits of economic and political feasibility. Already, the next generation of planned linear colliders is tens of kilometers long; a planned circular collider is 100 kilometers in circumference. Such massive projects will take years to build and strain ...

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New type of Weyl semimetal with quadratic double Weyl fermions [Physics]

02-Feb-2016 | Shin-Ming Huang; Su-Yang Xu; Ilya Belopolski; Chi-Cheng Lee; Guoqing Chang; Tay-Rong Chang; BaoKai Wang; Nasser Alid ..., Proceedings of the National Academy of Sciences current issue, 2016

Weyl semimetals have attracted worldwide attention due to their wide range of exotic properties predicted in theories. The experimental realization had remained elusive for a long time despite much effort. Very recently, the first Weyl semimetal has been discovered in an inversion-breaking, ...

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Profile of Benjamin Cravatt [Profiles]

02-Feb-2016 | Jennifer Viegas, Proceedings of the National Academy of Sciences current issue, 2016

Bridging the fields of chemistry and biology, Benjamin Cravatt and his research group have developed and applied technologies to discover biochemical pathways in mammalian biology and disease. Cravatt, who was elected to the National Academy of Sciences in 2014 and is chair of the Department of ...

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