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21,241 Newest Publications in proceedings of the national academy of sciences current issue

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matching the following criteria

Vitamin A-aldehyde adducts: AMD risk and targeted therapeutics [Medical Sciences]

26-Apr-2016 | Janet R. Sparrow, Proceedings of the National Academy of Sciences current issue, 2016

Although currently available treatment options for age-related macular degeneration (AMD) are limited, particularly for atrophic AMD, the identification of predisposing genetic variations has informed clinical studies addressing therapeutic options such as complement inhibitors and ...

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Cooperative folding near the downhill limit determined with amino acid resolution by hydrogen exchange [Biophysics and Computational Biology]

26-Apr-2016 | Wookyung Yu; Michael C. Baxa; Isabelle Gagnon; Karl F. Freed; Tobin R. Sosnick, Proceedings of the National Academy of Sciences current issue, 2016

The relationship between folding cooperativity and downhill, or barrier-free, folding of proteins under highly stabilizing conditions remains an unresolved topic, especially for proteins such as λ-repressor that fold on the microsecond timescale. Under aqueous conditions where downhill folding is ...

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Echolocating bats use future-target information for optimal foraging [Neuroscience]

26-Apr-2016 | Emyo Fujioka; Ikkyu Aihara; Miwa Sumiya; Kazuyuki Aihara; Shizuko Hiryu, Proceedings of the National Academy of Sciences current issue, 2016

When seeing or listening to an object, we aim our attention toward it. While capturing prey, many animal species focus their visual or acoustic attention toward the prey. However, for multiple prey items, the direction and timing of attention for effective foraging remain unknown. In this study, ...

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Correction for Bai et al., Structural analysis of the dodecameric proteasome activator PafE in Mycobacterium tuberculosis [Correction]

26-Apr-2016 | Proceedings of the National Academy of Sciences current issue, 2016

BIOCHEMISTRY Correction for “Structural analysis of the dodecameric proteasome activator PafE in Mycobacterium tuberculosis,” by Lin Bai, Kuan Hu, Tong Wang, Jordan M. Jastrab, K. Heran Darwin, and Huilin Li, which appeared in issue 14, April 5, 2016, of Proc Natl Acad Sci USA (113:E1983–E1992; ...

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Evolution of the knowledge system for agricultural development in the Yaqui Valley, Sonora, Mexico [Sustainability Science]

26-Apr-2016 | Ellen B. McCullough; Pamela A. Matson, Proceedings of the National Academy of Sciences current issue, 2016

Knowledge systems—networks of linked actors, organizations, and objects that perform a number of knowledge-related functions that link knowledge and know how with action—have played a key role in fostering agricultural development over the last 50 years. We examine the evolution of the knowledge ...

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Covert neurofeedback without awareness shapes cortical network spontaneous connectivity [Neuroscience]

26-Apr-2016 | Michal Ramot; Shany Grossman; Doron Friedman; Rafael Malach, Proceedings of the National Academy of Sciences current issue, 2016

Recent advances in blood oxygen level-dependent–functional MRI (BOLD-fMRI)-based neurofeedback reveal that participants can modulate neuronal properties. However, it is unknown whether such training effects can be introduced in the absence of participants' awareness that they are being trained. ...

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The role of innovative global institutions in linking knowledge and action [Sustainability Science]

26-Apr-2016 | Lorrae van Kerkhoff; Nicole A. Szlezák, Proceedings of the National Academy of Sciences current issue, 2016

It is becoming increasingly recognized that our collective ability to tackle complex problems will require the development of new, adaptive, and innovative institutional arrangements that can deal with rapidly changing knowledge and have effective learning capabilities. In this paper, we applied ...

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Correction for Eastwood et al., Tissue mechanics govern the rapidly adapting and symmetrical response to touch [Correction]

26-Apr-2016 | Proceedings of the National Academy of Sciences current issue, 2016

NEUROSCIENCE, ENGINEERING Correction for “Tissue mechanics govern the rapidly adapting and symmetrical response to touch,” by Amy L. Eastwood, Alessandro Sanzeni, Bryan C. Petzold, Sung-Jin Park, Massimo Vergassola, Beth L. Pruitt, and Miriam B. Goodman, which appeared in issue 50, December 15, ...

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Gene therapy, CMT1X, and the inherited neuropathies [Neuroscience]

26-Apr-2016 | Michael E. Shy, Proceedings of the National Academy of Sciences current issue, 2016

In PNAS, Kagiava et al. (1) report their rescue of the X-linked form of Charcot–Marie–Tooth disease (CMT1X) in mice, through the use of a single intrathecal injection with a lentiviral vector. The vector expresses the gap junction beta 1 (GJB1) gene and its encoded protein connexin32 (Cx32), ...

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Moral consequences of becoming unemployed [Economic Sciences]

26-Apr-2016 | Abigail Barr; Luis Miller; Paloma Ubeda, Proceedings of the National Academy of Sciences current issue, 2016

We test the conjecture that becoming unemployed erodes the extent to which a person acknowledges earned entitlement. We use behavioral experiments to generate incentive-compatible measures of individuals’ tendencies to acknowledge earned entitlement and incorporate these experiments in a ...

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