My watch list
my.chemeurope.com  
Login  

297 Newest Publications in proceedings of the national academy of sciences current issue

rss
matching the following criteria

In vivo treatment of Helicobacter pylori infection with liposomal linolenic acid reduces colonization and ameliorates inflammation [Engineering]

09-12-2014 | Soracha Thamphiwatana; Weiwei Gao; Marygorret Obonyo; Liangfang Zhang, Proceedings of the National Academy of Sciences current issue, 2014

Helicobacter pylori infection is marked by a vast prevalence and strong association with various gastric diseases, including gastritis, peptic ulcers, and gastric cancer. Because of the rapid emergence of H. pylori strains resistant to existing antibiotics, current treatment regimens show a rapid ...

more

Amino acid modified Ni catalyst exhibits reversible H2 oxidation/production over a broad pH range at elevated temperatures [Chemistry]

18-11-2014 | Arnab Dutta; Daniel L. DuBois; John A. S. Roberts; Wendy J. Shaw, Proceedings of the National Academy of Sciences current issue, 2014

Hydrogenases interconvert H2 and protons at high rates and with high energy efficiencies, providing inspiration for the development of molecular catalysts. Studies designed to determine how the protein scaffold can influence a catalytically active site have led to the synthesis of amino acid ...

more

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance [Medical Sciences]

18-11-2014 | Yasmeen Rahimi; João-Paulo G. Camporez; Max C. Petersen; Dominik Pesta; Rachel J. Perry; Michael J. Jurczak; Gary W. ..., Proceedings of the National Academy of Sciences current issue, 2014

The pyruvate dehydrogenase complex (PDH) has been hypothesized to link lipid exposure to skeletal muscle insulin resistance through a glucose-fatty acid cycle in which increased fatty acid oxidation increases acetyl-CoA concentrations, thereby inactivating PDH and decreasing glucose oxidation. ...

more

Use of protein cross-linking and radiolytic footprinting to elucidate PsbP and PsbQ interactions within higher plant Photosystem II [Plant Biology]

11-11-2014 | Manjula P. Mummadisetti; Laurie K. Frankel; Henry D. Bellamy; Larry Sallans; Jost S. Goettert; Michal Brylinski; Pat ..., Proceedings of the National Academy of Sciences current issue, 2014

Protein cross-linking and radiolytic footprinting coupled with high-resolution mass spectrometry were used to examine the structure of PsbP and PsbQ when they are bound to Photosystem II. In its bound state, the N-terminal 15-amino-acid residue domain of PsbP, which is unresolved in current ...

more

Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway [Medical Sciences]

07-10-2014 | Gabrielle Fredman; Lale Ozcan; Stefano Spolitu; Jason Hellmann; Matthew Spite; Johannes Backs; Ira Tabas, Proceedings of the National Academy of Sciences current issue, 2014

Imbalances between proinflammatory and proresolving mediators can lead to chronic inflammatory diseases. The balance of arachidonic acid-derived mediators in leukocytes is thought to be achieved through intracellular localization of 5-lipoxygenase (5-LOX): nuclear 5-LOX favors the biosynthesis of ...

more

Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid [Neuroscience]

16-09-2014 | Yannick Comoglio; Joshua Levitz; Michael A. Kienzler; Florian Lesage; Ehud Y. Isacoff; Guillaume Sandoz, Proceedings of the National Academy of Sciences current issue, 2014

Membrane lipids serve as second messengers and docking sites for proteins and play central roles in cell signaling. A major question about lipid signaling is whether diffusible lipids can selectively target specific proteins. One family of lipid-regulated membrane proteins is the TWIK-related K ...

more

Molecular mechanism of pH-dependent substrate transport by an arginine-agmatine antiporter [Biochemistry]

02-09-2014 | Sheng Wang; Renhong Yan; Xi Zhang; Qi Chu; Yigong Shi, Proceedings of the National Academy of Sciences current issue, 2014

Enteropathogenic bacteria, exemplified by Escherichia coli, rely on acid-resistance systems (ARs) to survive the acidic environment of the stomach. AR3 consumes intracellular protons through decarboxylation of arginine (Arg) in the cytoplasm and exchange of the reaction product agmatine (Agm) ...

more

Robustness against serum neutralization of a poliovirus type 1 from a lethal epidemic of poliomyelitis in the Republic of Congo in 2010 [Microbiology]

02-09-2014 | Jan Felix Drexler; Gilda Grard; Alexander N. Lukashev; Liubov I. Kozlovskaya; Sindy Böttcher; Gökhan Uslu; Johan Rei ..., Proceedings of the National Academy of Sciences current issue, 2014

In 2010, a large outbreak of poliomyelitis with unusual 47% lethality occurred in Pointe Noire, Republic of Congo. Vaccine-mediated immunity against the outbreak virus was never investigated. A wild poliovirus 1 (WPV1) isolated from a fatal case (termed PV1-RC2010) showed a previously unknown ...

more

Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids [Microbiology]

26-08-2014 | John P. Santa Maria, Jr.; Ama Sadaka; Samir H. Moussa; Stephanie Brown; Yanjia J. Zhang; Eric J. Rubin; Michael S. G ..., Proceedings of the National Academy of Sciences current issue, 2014

Staphylococcus aureus contains two distinct teichoic acid (TA) polymers, lipoteichoic acid (LTA) and wall teichoic acid (WTA), which are proposed to play redundant roles in regulating cell division. To gain insight into the underlying biology of S. aureus TAs, we used a small molecule inhibitor ...

more

Synthesis and scavenging role of furan fatty acids [Microbiology]

19-08-2014 | Rachelle A. S. Lemke; Amelia C. Peterson; Eva C. Ziegelhoffer; Michael S. Westphall; Henrik Tjellström; Joshua J. Co ..., Proceedings of the National Academy of Sciences current issue, 2014

Fatty acids play important functional and protective roles in living systems. This paper reports on the synthesis of a previously unidentified 19 carbon furan-containing fatty acid, 10,13-epoxy-11-methyl-octadecadienoate (9-(3-methyl-5-pentylfuran-2-yl)nonanoic acid) (19Fu-FA), in phospholipids ...

more

Page 1 From 30
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE