My watch list
my.chemeurope.com  
Login  

317 Newest Publications in proceedings of the national academy of sciences current issue

rss
matching the following criteria

Reply to van de Sandt and Rimmelzwaan: Matching epitope display with functional avidity [Biological Sciences]

12-May-2015 | Derin B. Keskin; Bruce R. Reinhold; Guang Lan Zhang; Alexander R. Ivanov; Barry L. Karger; Ellis L. Reinherz, Proceedings of the National Academy of Sciences current issue, 2015

We appreciate the comments of van de Sandt and Rimmelzwaan (1) on our paper (2), as well as the opportunity to respond. First, we agree that in Berkhoff et al. (3) single alanine replacements resulted in reduced kinetics of viral replication. Nonetheless, to claim “a reduction of progeny virus ...

more

Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases [Biochemistry]

12-May-2015 | Robert T. Byrne; Huw T. Jenkins; Daniel T. Peters; Fiona Whelan; James Stowell; Naveed Aziz; Pavel Kasatsky; Marina ..., Proceedings of the National Academy of Sciences current issue, 2015

The reduction of specific uridines to dihydrouridine is one of the most common modifications in tRNA. Increased levels of the dihydrouridine modification are associated with cancer. Dihydrouridine synthases (Dus) from different subfamilies selectively reduce distinct uridines, located at ...

more

Structure-relaxation mechanism for the response of T4 lysozyme cavity mutants to hydrostatic pressure [Biophysics and Computational Biology]

12-May-2015 | Michael T. Lerch; Carlos J. López; Zhongyu Yang; Margaux J. Kreitman; Joseph Horwitz; Wayne L. Hubbell, Proceedings of the National Academy of Sciences current issue, 2015

Application of hydrostatic pressure shifts protein conformational equilibria in a direction to reduce the volume of the system. A current view is that the volume reduction is dominated by elimination of voids or cavities in the protein interior via cavity hydration, although an alternative ...

more

Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response [Immunology and Inflammation]

21-Apr-2015 | Emilie K. Grasset; Amanda Duhlin; Hanna E. Agardh; Olga Ovchinnikova; Thomas Hägglöf; Mattias N. Forsell; Gabrielle ..., Proceedings of the National Academy of Sciences current issue, 2015

The B-cell response in atherosclerosis is directed toward oxidation-specific epitopes such as phosphorylcholine (PC) that arise during disease-driven oxidation of self-antigens. PC-bearing antigens have been used to induce atheroprotective antibodies against modified low-density lipoproteins ...

more

Cortical activity is more stable when sensory stimuli are consciously perceived [Neuroscience]

21-Apr-2015 | Aaron Schurger; Ioannis Sarigiannidis; Lionel Naccache; Jacobo D. Sitt; Stanislas Dehaene, Proceedings of the National Academy of Sciences current issue, 2015

According to recent evidence, stimulus-tuned neurons in the cerebral cortex exhibit reduced variability in firing rate across trials, after the onset of a stimulus. However, in order for a reduction in variability to be directly relevant to perception and behavior, it must be realized within ...

more

Place field expansion after focal MEC inactivations is consistent with loss of Fourier components and path integrator gain reduction [Neuroscience]

31-Mar-2015 | Jake Ormond; Bruce L. McNaughton, Proceedings of the National Academy of Sciences current issue, 2015

Both hippocampal place fields and medial entorhinal cortex (MEC) grid fields increase in scale along the dorsoventral axis. Because the connections from MEC to hippocampus are topographically organized and divergent, it has been hypothesized that place fields are generated by a Fourier-like ...

more

Mitochondrial metabolism is regulated by thioredoxin [Plant Biology]

17-Mar-2015 | Ian Max Møller, Proceedings of the National Academy of Sciences current issue, 2015

In PNAS, Daloso et al. (1) show that, in plant cells, the activities of two enzymes, succinate dehydrogenase and fumarase, in the tricarboxylic acid (TCA) cycle in the mitochondria, as well as one cytosolic enzyme associated with the cycle (ATP-citrate lyase), are regulated by reversible ...

more

Methane emissions from natural gas infrastructure and use in the urban region of Boston, Massachusetts [Sustainability Science]

17-Feb-2015 | Kathryn McKain; Adrian Down; Steve M. Raciti; John Budney; Lucy R. Hutyra; Cody Floerchinger; Scott C. Herndon; Thom ..., Proceedings of the National Academy of Sciences current issue, 2015

Methane emissions from natural gas delivery and end use must be quantified to evaluate the environmental impacts of natural gas and to develop and assess the efficacy of emission reduction strategies. We report natural gas emission rates for 1 y in the urban region of Boston, using a ...

more

Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase [Biophysics and Computational Biology]

17-Feb-2015 | Vivek Sharma; Giray Enkavi; Ilpo Vattulainen; Tomasz Róg; Mårten Wikström, Proceedings of the National Academy of Sciences current issue, 2015

Molecular oxygen acts as the terminal electron sink in the respiratory chains of aerobic organisms. Cytochrome c oxidase in the inner membrane of mitochondria and the plasma membrane of bacteria catalyzes the reduction of oxygen to water, and couples the free energy of the reaction to proton ...

more

Plasma butyrylcholinesterase regulates ghrelin to control aggression [Neuroscience]

17-Feb-2015 | Vicky Ping Chen; Yang Gao; Liyi Geng; Robin J. Parks; Yuan-Ping Pang; Stephen Brimijoin, Proceedings of the National Academy of Sciences current issue, 2015

Ongoing mouse studies of a proposed therapy for cocaine abuse based on viral gene transfer of butyrylcholinesterase (BChE) mutated for accelerated cocaine hydrolysis have yielded surprising effects on aggression. Further investigation has linked these effects to a reduction in circulating ...

more

Page 1 From 32
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE