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387 Newest Publications in proceedings of the national academy of sciences current issue

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Magnetotactic bacteria form magnetite from a phosphate-rich ferric hydroxide via nanometric ferric (oxyhydr)oxide intermediates [Microbiology]

10-09-2013 | Jens Baumgartner; Guillaume Morin; Nicolas Menguy; Teresa Perez Gonzalez; Marc Widdrat; Julie Cosmidis; Damien Faivre, Proceedings of the National Academy of Sciences current issue, 2013

The iron oxide mineral magnetite (Fe3O4) is produced by various organisms to exploit magnetic and mechanical properties. Magnetotactic bacteria have become one of the best model organisms for studying magnetite biomineralization, as their genomes are sequenced and tools are available for their ...

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Comparative genomics boosts target prediction for bacterial small RNAs [Genetics]

10-09-2013 | Patrick R. Wright; Andreas S. Richter; Kai Papenfort; Martin Mann; Jörg Vogel; Wolfgang R. Hess; Rolf Backofen; Jens ..., Proceedings of the National Academy of Sciences current issue, 2013

Small RNAs (sRNAs) constitute a large and heterogeneous class of bacterial gene expression regulators. Much like eukaryotic microRNAs, these sRNAs typically target multiple mRNAs through short seed pairing, thereby acting as global posttranscriptional regulators. In some bacteria, evidence for ...

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Analysis of Chlamydomonas thiamin metabolism in vivo reveals riboswitch plasticity [Biochemistry]

03-09-2013 | Michael Moulin; Ginnie T. D. T. Nguyen; Mark A. Scaife; Alison G. Smith; Teresa B. Fitzpatrick, Proceedings of the National Academy of Sciences current issue, 2013

Thiamin (vitamin B1) is an essential micronutrient needed as a cofactor for many central metabolic enzymes. Animals must have thiamin in their diet, whereas bacteria, fungi, and plants can biosynthesize it de novo from the condensation of a thiazole and a pyrimidine moiety. Although the routes to ...

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Correction for Gushchin et al., Structural insights into the proton pumping by unusual proteorhodopsin from nonmarine bacteria [Correction]

03-09-2013 | Proceedings of the National Academy of Sciences current issue, 2013

BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for “Structural insights into the proton pumping by unusual proteorhodopsin from nonmarine bacteria,” by Ivan Gushchin, Pavel Chervakov, Pavel Kuzmichev, Alexander N. Popov, Ekaterina Round, Valentin Borshchevskiy, Andrii Ishchenko, Lada ...

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A physical explanation of the temperature dependence of physiological processes mediated by cilia and flagella [Ecology]

03-09-2013 | Stuart Humphries, Proceedings of the National Academy of Sciences current issue, 2013

The majority of biological rates are known to exhibit temperature dependence. Here I reveal a direct link between temperature and ecologically relevant rates such as swimming speeds in Archaea, Bacteria, and Eukaryotes as well as fluid-pumping and filtration rates in many metazoans, and show that ...

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Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A [Biophysics and Computational Biology]

03-09-2013 | Daohua Jiang; Yan Zhao; Xianping Wang; Junping Fan; Jie Heng; Xuehui Liu; Wei Feng; Xusheng Kang; Bo Huang; Jianfeng ..., Proceedings of the National Academy of Sciences current issue, 2013

The major facilitator superfamily (MFS) is the largest family of secondary active transporters and is present in all life kingdoms. Detailed structural basis of the substrate transport and energy-coupling mechanisms of these proteins remain to be elucidated. YajR is a putative proton-driven MFS ...

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Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance [Microbiology]

27-08-2013 | Nicole M. Vega; Kyle R. Allison; Amanda N. Samuels; Mark S. Klempner; James J. Collins, Proceedings of the National Academy of Sciences current issue, 2013

Bacterial communication plays an important role in many population-based phenotypes and interspecies interactions, including those in host environments. These interspecies interactions may prove critical to some infectious diseases, and it follows that communication between pathogenic bacteria ...

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Gram-positive siderophore-shuttle with iron-exchange from Fe-siderophore to apo-siderophore by Bacillus cereus YxeB [Biochemistry]

20-08-2013 | Tatsuya Fukushima; Benjamin E. Allred; Allyson K. Sia; Rita Nichiporuk; Ulla N. Andersen; Kenneth N. Raymond, Proceedings of the National Academy of Sciences current issue, 2013

Small molecule iron-chelators, siderophores, are very important in facilitating the acquisition of Fe(III), an essential element for pathogenic bacteria. Many Gram-negative outer-membrane transporters and Gram-positive lipoprotein siderophore-binding proteins have been characterized, and the ...

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MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection [Immunology]

13-08-2013 | Anda Meierovics; Wei-Jen Chua Yankelevich; Siobhán C. Cowley, Proceedings of the National Academy of Sciences current issue, 2013

Mucosa-associated invariant T (MAIT) cells are “innate” T cells that express an invariant T-cell receptor α-chain restricted by the nonclassical MHC class I molecule MHC-related protein 1 (MR1). A recent discovery that MR1 presents vitamin B metabolites, presumably from pathogenic and/or ...

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Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses [Microbiology]

13-08-2013 | Annette Kampa; Andrey N. Gagunashvili; Tobias A. M. Gulder; Brandon I. Morinaka; Cristina Daolio; Markus Godejohann; ..., Proceedings of the National Academy of Sciences current issue, 2013

Bacteria are a major source of natural products that provide rich opportunities for both chemical and biological investigation. Although the vast majority of known bacterial metabolites derive from free-living organisms, increasing evidence supports the widespread existence of chemically prolific ...

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