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410 Newest Publications in proceedings of the national academy of sciences current issue

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matching the following criteria

Bloom of resident antibiotic-resistant bacteria in soil following manure fertilization [Microbiology]

21-10-2014 | Nikolina Udikovic-Kolic; Fabienne Wichmann; Nichole A. Broderick; Jo Handelsman, Proceedings of the National Academy of Sciences current issue, 2014

The increasing prevalence of antibiotic-resistant bacteria is a global threat to public health. Agricultural use of antibiotics is believed to contribute to the spread of antibiotic resistance, but the mechanisms by which many agricultural practices influence resistance remain obscure. Although ...

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Precisely modulated pathogenicity island interference with late phage gene transcription [Microbiology]

07-10-2014 | Geeta Ram; John Chen; Hope F. Ross; Richard P. Novick, Proceedings of the National Academy of Sciences current issue, 2014

Having gone to great evolutionary lengths to develop resistance to bacteriophages, bacteria have come up with resistance mechanisms directed at every aspect of the bacteriophage life cycle. Most genes involved in phage resistance are carried by plasmids and other mobile genetic elements, ...

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Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages [Microbiology]

07-10-2014 | Shiho Suzuki; Hitomi Mimuro; Minsoo Kim; Michinaga Ogawa; Hiroshi Ashida; Takahito Toyotome; Luigi Franchi; Masato S ..., Proceedings of the National Academy of Sciences current issue, 2014

When nucleotide-binding oligomerization domain–like receptors (NLRs) sense cytosolic-invading bacteria, they induce the formation of inflammasomes and initiate an innate immune response. In quiescent cells, inflammasome activity is tightly regulated to prevent excess inflammation and cell death. ...

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Complementary symbiont contributions to plant decomposition in a fungus-farming termite [Evolution]

07-10-2014 | Michael Poulsen; Haofu Hu; Cai Li; Zhensheng Chen; Luohao Xu; Saria Otani; Sanne Nygaard; Tania Nobre; Sylvia Klauba ..., Proceedings of the National Academy of Sciences current issue, 2014

Termites normally rely on gut symbionts to decompose organic matter but the Macrotermitinae domesticated Termitomyces fungi to produce their own food. This transition was accompanied by a shift in the composition of the gut microbiota, but the complementary roles of these bacteria in the ...

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Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins [Biochemistry]

07-10-2014 | Mark A. Herzik, Jr.; Rohan Jonnalagadda; John Kuriyan; Michael A. Marletta, Proceedings of the National Academy of Sciences current issue, 2014

Heme-nitric oxide/oxygen (H-NOX) binding domains are a recently discovered family of heme-based gas sensor proteins that are conserved across eukaryotes and bacteria. Nitric oxide (NO) binding to the heme cofactor of H-NOX proteins has been implicated as a regulatory mechanism for processes ...

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In This Issue [This Week in PNAS]

16-09-2014 | Proceedings of the National Academy of Sciences current issue, 2014

Penetration of bacterial biofilms in skin by ionic liquids Biofilms that protect bacteria causing skin infections pose an antibiotic-resistant barrier to treatment. To penetrate biofilm layers, as well as stratum corneum skin layers, which also hinder drug delivery, Michael Zakrewsky et al. (pp. ...

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Xylella fastidiosa outer membrane vesicles modulate plant colonization by blocking attachment to surfaces [Microbiology]

16-09-2014 | Michael Ionescu; Paulo A. Zaini; Clelia Baccari; Sophia Tran; Aline M. da Silva; Steven E. Lindow, Proceedings of the National Academy of Sciences current issue, 2014

Outer membrane vesicles (OMVs) of Gram-negative bacteria have been studied intensively in recent years, primarily in their role in delivering virulence factors and antigens during pathogenesis. However, the near ubiquity of their production suggests that they may play other roles, such as ...

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Commensal bacteria protect against food allergen sensitization [Immunology and Inflammation]

09-09-2014 | Andrew T. Stefka; Taylor Feehley; Prabhanshu Tripathi; Ju Qiu; Kathy McCoy; Sarkis K. Mazmanian; Melissa Y. Tjota; G ..., Proceedings of the National Academy of Sciences current issue, 2014

Environmentally induced alterations in the commensal microbiota have been implicated in the increasing prevalence of food allergy. We show here that sensitization to a food allergen is increased in mice that have been treated with antibiotics or are devoid of a commensal microbiota. By ...

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Shewanella oneidensis MR-1 nanowires are outer membrane and periplasmic extensions of the extracellular electron transport components [Microbiology]

02-09-2014 | Sahand Pirbadian; Sarah E. Barchinger; Kar Man Leung; Hye Suk Byun; Yamini Jangir; Rachida A. Bouhenni; Samantha B. ..., Proceedings of the National Academy of Sciences current issue, 2014

Bacterial nanowires offer an extracellular electron transport (EET) pathway for linking the respiratory chain of bacteria to external surfaces, including oxidized metals in the environment and engineered electrodes in renewable energy devices. Despite the global, environmental, and technological ...

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Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes [Microbiology]

02-09-2014 | Meiling Zhang; Jonathan R. Chekan; Dylan Dodd; Pei-Ying Hong; Lauren Radlinski; Vanessa Revindran; Satish K. Nair; R ..., Proceedings of the National Academy of Sciences current issue, 2014

Enzymes that degrade dietary and host-derived glycans represent the most abundant functional activities encoded by genes unique to the human gut microbiome. However, the biochemical activities of a vast majority of the glycan-degrading enzymes are poorly understood. Here, we use transcriptome ...

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