My watch list
my.chemeurope.com  
Login  

447 Newest Publications in proceedings of the national academy of sciences current issue

rss
matching the following criteria

Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIAGlc [Biochemistry]

24-Feb-2015 | Parameswaran Hariharan; Dhandayuthapani Balasubramaniam; Alan Peterkofsky; H. Ronald Kaback; Lan Guan, Proceedings of the National Academy of Sciences current issue, 2015

In a variety of bacteria, the phosphotransferase protein IIAGlc plays a key regulatory role in catabolite repression in addition to its role in the vectorial phosphorylation of glucose catalyzed by the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). The lactose permease (LacY) ...

more

Quorum sensing and policing of Pseudomonas aeruginosa social cheaters [Microbiology]

17-Feb-2015 | Meizhen Wang; Amy L. Schaefer; Ajai A. Dandekar; E. Peter Greenberg, Proceedings of the National Academy of Sciences current issue, 2015

The bacterium Pseudomonas aeruginosa is an opportunistic human pathogen that uses a quorum sensing signal cascade to activate expression of dozens of genes when sufficient population densities have been reached. Quorum sensing controls production of several key virulence factors, including ...

more

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence [Microbiology]

17-Feb-2015 | TuAnh Ngoc Huynh; Shukun Luo; Daniel Pensinger; John-Demian Sauer; Liang Tong; Joshua J. Woodward, Proceedings of the National Academy of Sciences current issue, 2015

The nucleotide cyclic di-3′,5′- adenosine monophosphate (c-di-AMP) was recently identified as an essential and widespread second messenger in bacterial signaling. Among c-di-AMP–producing bacteria, altered nucleotide levels result in several physiological defects and attenuated virulence. Thus, a ...

more

Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase [Biophysics and Computational Biology]

17-Feb-2015 | Vivek Sharma; Giray Enkavi; Ilpo Vattulainen; Tomasz Róg; Mårten Wikström, Proceedings of the National Academy of Sciences current issue, 2015

Molecular oxygen acts as the terminal electron sink in the respiratory chains of aerobic organisms. Cytochrome c oxidase in the inner membrane of mitochondria and the plasma membrane of bacteria catalyzes the reduction of oxygen to water, and couples the free energy of the reaction to proton ...

more

Inhibition of the {beta}-barrel assembly machine by a peptide that binds BamD [Biochemistry]

17-Feb-2015 | Christine L. Hagan; Joseph S. Wzorek; Daniel Kahne, Proceedings of the National Academy of Sciences current issue, 2015

The protein complex that assembles integral membrane β-barrel proteins in the outer membranes of Gram-negative bacteria is an attractive target in the development of new antibiotics. This complex, the β-barrel assembly machine (Bam), contains two essential proteins, BamA and BamD. We have ...

more

Noncanonical coproporphyrin-dependent bacterial heme biosynthesis pathway that does not use protoporphyrin [Microbiology]

17-Feb-2015 | Harry A. Dailey; Svetlana Gerdes; Tamara A. Dailey; Joseph S. Burch; John D. Phillips, Proceedings of the National Academy of Sciences current issue, 2015

It has been generally accepted that biosynthesis of protoheme (heme) uses a common set of core metabolic intermediates that includes protoporphyrin. Herein, we show that the Actinobacteria and Firmicutes (high-GC and low-GC Gram-positive bacteria) are unable to synthesize protoporphyrin. Instead, ...

more

Differential RNA-seq of Vibrio cholerae identifies the VqmR small RNA as a regulator of biofilm formation [Microbiology]

17-Feb-2015 | Kai Papenfort; Konrad U. Förstner; Jian-Ping Cong; Cynthia M. Sharma; Bonnie L. Bassler, Proceedings of the National Academy of Sciences current issue, 2015

Quorum sensing (QS) is a process of cell-to-cell communication that enables bacteria to transition between individual and collective lifestyles. QS controls virulence and biofilm formation in Vibrio cholerae, the causative agent of cholera disease. Differential RNA sequencing (RNA-seq) of ...

more

Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid {alpha}-glycosyltransferase [Microbiology]

10-Feb-2015 | Solmaz Sobhanifar; Liam James Worrall; Robert J. Gruninger; Gregory A. Wasney; Markus Blaukopf; Lars Baumann; Emilie ..., Proceedings of the National Academy of Sciences current issue, 2015

Unique to Gram-positive bacteria, wall teichoic acids are anionic glycopolymers cross-stitched to a thick layer of peptidoglycan. The polyol phosphate subunits of these glycopolymers are decorated with GlcNAc sugars that are involved in phage binding, genetic exchange, host antibody response, ...

more

Chemical signature of magnetotactic bacteria [Earth, Atmospheric, and Planetary Sciences]

10-Feb-2015 | Matthieu Amor; Vincent Busigny; Mickaël Durand-Dubief; Mickaël Tharaud; Georges Ona-Nguema; Alexandre Gélabert; Edou ..., Proceedings of the National Academy of Sciences current issue, 2015

There are longstanding and ongoing controversies about the abiotic or biological origin of nanocrystals of magnetite. On Earth, magnetotactic bacteria perform biomineralization of intracellular magnetite nanoparticles under a controlled pathway. These bacteria are ubiquitous in modern natural ...

more

Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa [Immunology and Inflammation]

10-Feb-2015 | Natalia V. Kirienko; Frederick M. Ausubel; Gary Ruvkun, Proceedings of the National Academy of Sciences current issue, 2015

In the arms race of bacterial pathogenesis, bacteria produce an array of toxins and virulence factors that disrupt core host processes. Hosts mitigate the ensuing damage by responding with immune countermeasures. The iron-binding siderophore pyoverdin is a key virulence mediator of the human ...

more

Page 1 From 45
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE