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425 Newest Publications in proceedings of the national academy of sciences current issue

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matching the following criteria

News Feature: Animals that self-medicate [News Feature]

09-12-2014 | Joel Shurkin, Proceedings of the National Academy of Sciences current issue, 2014

Many animal species have created their own pharmacies from ingredients that commonly occur in nature. Birds, bees, lizards, elephants, and chimpanzees all share a survival trait: They self-medicate. These animals eat things that make them feel better, or prevent disease, or kill parasites like ...

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Global discovery of colonization determinants in the squid symbiont Vibrio fischeri [Microbiology]

02-12-2014 | John F. Brooks II; Mattias C. Gyllborg; David C. Cronin; Sarah J. Quillin; Celeste A. Mallama; Randi Foxall; Cheryl ..., Proceedings of the National Academy of Sciences current issue, 2014

Animal epithelial tissue becomes reproducibly colonized by specific environmental bacteria. The bacteria (microbiota) perform critical functions for the host’s tissue development, immune system development, and nutrition; yet the processes by which bacterial diversity in the environment is ...

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XerD-mediated FtsK-independent integration of TLC{phi} into the Vibrio cholerae genome [Microbiology]

25-11-2014 | Caroline Midonet; Bhabatosh Das; Evelyne Paly; Francois-Xavier Barre, Proceedings of the National Academy of Sciences current issue, 2014

As in most bacteria, topological problems arising from the circularity of the two Vibrio cholerae chromosomes, chrI and chrII, are resolved by the addition of a crossover at a specific site of each chromosome, dif, by two tyrosine recombinases, XerC and XerD. The reaction is under the control of ...

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Gill bacteria enable a novel digestive strategy in a wood-feeding mollusk [Microbiology]

25-11-2014 | Roberta M. O’Connor; Jennifer M. Fung; Koty H. Sharp; Jack S. Benner; Colleen McClung; Shelley Cushing; Elizabeth R. ..., Proceedings of the National Academy of Sciences current issue, 2014

Bacteria play many important roles in animal digestive systems, including the provision of enzymes critical to digestion. Typically, complex communities of bacteria reside in the gut lumen in direct contact with the ingested materials they help to digest. Here, we demonstrate a previously ...

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Acceleration of evolutionary spread by long-range dispersal [Applied Physical Sciences]

18-11-2014 | Oskar Hallatschek; Daniel S. Fisher, Proceedings of the National Academy of Sciences current issue, 2014

The spreading of evolutionary novelties across populations is the central element of adaptation. Unless populations are well mixed (like bacteria in a shaken test tube), the spreading dynamics depend not only on fitness differences but also on the dispersal behavior of the species. Spreading at a ...

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Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3 [Biochemistry]

18-11-2014 | Bei Gong; Minsang Shin; Jiali Sun; Che-Hun Jung; Edward L. Bolt; John van der Oost; Jeong-Sun Kim, Proceedings of the National Academy of Sciences current issue, 2014

Mobile genetic elements in bacteria are neutralized by a system based on clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins. Type I CRISPR-Cas systems use a “Cascade” ribonucleoprotein complex to guide RNA specifically to complementary ...

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Horizontal transfer beyond genes [Microbiology]

11-11-2014 | Eugene V. Koonin, Proceedings of the National Academy of Sciences current issue, 2014

Horizontal gene transfer (HGT) is a major process in the evolution of bacteria and archaea (1–3) that is thought to be the principal source of functional innovation in microbial evolution (4, 5). The signal of vertical, tree-like evolution is detectable primarily among genes encoding components ...

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Selective allosteric coupling in core chemotaxis signaling complexes [Biochemistry]

11-11-2014 | Mingshan Li; Gerald L. Hazelbauer, Proceedings of the National Academy of Sciences current issue, 2014

Bacterial chemotaxis is mediated by signaling complexes that sense chemical gradients and direct bacteria to favorable environments by controlling a histidine kinase as a function of chemoreceptor ligand occupancy. Core signaling complexes contain two trimers of transmembrane chemoreceptor ...

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Transfer of noncoding DNA drives regulatory rewiring in bacteria [Microbiology]

11-11-2014 | Yaara Oren; Mark B. Smith; Nathan I. Johns; Millie Kaplan Zeevi; Dvora Biran; Eliora Z. Ron; Jukka Corander; Harris ..., Proceedings of the National Academy of Sciences current issue, 2014

Understanding the mechanisms that generate variation is a common pursuit unifying the life sciences. Bacteria represent an especially striking puzzle, because closely related strains possess radically different metabolic and ecological capabilities. Differences in protein repertoire arising from ...

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Replication initiator DnaA binds at the Caulobacter centromere and enables chromosome segregation [Microbiology]

11-11-2014 | Paola E. Mera; Virginia S. Kalogeraki; Lucy Shapiro, Proceedings of the National Academy of Sciences current issue, 2014

During cell division, multiple processes are highly coordinated to faithfully generate genetically equivalent daughter cells. In bacteria, the mechanisms that underlie the coordination of chromosome replication and segregation are poorly understood. Here, we report that the conserved replication ...

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