My watch list
my.chemeurope.com  
Login  

1,627 Newest Publications in proceedings of the national academy of sciences current issue

rss
matching the following criteria

Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy [Biophysics and Computational Biology]

23-Jun-2015 | Wing Sin Chiu; Natalie A. Belsey; Natalie L. Garrett; Julian Moger; M. Begoña Delgado-Charro; Richard H. Guy, Proceedings of the National Academy of Sciences current issue, 2015

The effective treatment of diseases of the nail remains an important unmet medical need, primarily because of poor drug delivery. To address this challenge, the diffusion, in real time, of topically applied chemicals into the human nail has been visualized and characterized using stimulated Raman ...

more

Inference of transcriptional regulation in cancers [Biophysics and Computational Biology]

23-Jun-2015 | Peng Jiang; Matthew L. Freedman; Jun S. Liu; Xiaole Shirley Liu, Proceedings of the National Academy of Sciences current issue, 2015

Despite the rapid accumulation of tumor-profiling data and transcription factor (TF) ChIP-seq profiles, efforts integrating TF binding with the tumor-profiling data to understand how TFs regulate tumor gene expression are still limited. To systematically search for cancer-associated TFs, we ...

more

Gate-controlled proton diffusion and protonation-induced ratchet motion in the stator of the bacterial flagellar motor [Biophysics and Computational Biology]

23-Jun-2015 | Yasutaka Nishihara; Akio Kitao, Proceedings of the National Academy of Sciences current issue, 2015

The proton permeation process of the stator complex MotA/B in the flagellar motor of Escherichia coli was investigated. The atomic model structure of the transmembrane part of MotA/B was constructed based on the previously published disulfide cross-linking and tryptophan scanning mutations. The ...

more

Asymptomatic spread of huanglongbing and implications for disease control [Plant Biology]

16-Jun-2015 | Jo Ann Lee; Susan E. Halbert; William O. Dawson; Cecile J. Robertson; James E. Keesling; Burton H. Singer, Proceedings of the National Academy of Sciences current issue, 2015

Huanglongbing (HLB) is a bacterial infection of citrus trees transmitted by the Asian citrus psyllid Diaphorina citri. Mitigation of HLB has focused on spraying of insecticides to reduce the psyllid population and removal of trees when they first show symptoms of the disease. These interventions ...

more

Direct observation of DNA overwinding by reverse gyrase [Biophysics and Computational Biology]

16-Jun-2015 | Taisaku Ogawa; Katsunori Yogo; Shou Furuike; Kazuo Sutoh; Akihiko Kikuchi; Kazuhiko Kinosita Jr., Proceedings of the National Academy of Sciences current issue, 2015

Reverse gyrase, found in hyperthermophiles, is the only enzyme known to overwind (introduce positive supercoils into) DNA. The ATP-dependent activity, detected at >70 °C, has so far been studied solely by gel electrophoresis; thus, the reaction dynamics remain obscure. Here, we image the ...

more

Identifying localized changes in large systems: Change-point detection for biomolecular simulations [Biophysics and Computational Biology]

16-Jun-2015 | Zhou Fan; Ron O. Dror; Thomas J. Mildorf; Stefano Piana; David E. Shaw, Proceedings of the National Academy of Sciences current issue, 2015

Research on change-point detection, the classical problem of detecting abrupt changes in sequential data, has focused predominantly on datasets with a single observable. A growing number of time series datasets, however, involve many observables, often with the property that a given change ...

more

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers [Biophysics and Computational Biology]

16-Jun-2015 | Harindranath Kadavath; Romina V. Hofele; Jacek Biernat; Satish Kumar; Katharina Tepper; Henning Urlaub; Eckhard Mand ..., Proceedings of the National Academy of Sciences current issue, 2015

The structure, dynamic behavior, and spatial organization of microtubules are regulated by microtubule-associated proteins. An important microtubule-associated protein is the protein Tau, because its microtubule interaction is impaired in the course of Alzheimer’s disease and several other ...

more

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy [Biophysics and Computational Biology]

16-Jun-2015 | András Micsonai; Frank Wien; Linda Kernya; Young-Ho Lee; Yuji Goto; Matthieu Réfrégiers; József Kardos, Proceedings of the National Academy of Sciences current issue, 2015

Circular dichroism (CD) spectroscopy is a widely used technique for the study of protein structure. Numerous algorithms have been developed for the estimation of the secondary structure composition from the CD spectra. These methods often fail to provide acceptable results on α/β-mixed or ...

more

Calcium sensor kinase activates potassium uptake systems in gland cells of Venus flytraps [Plant Biology]

09-Jun-2015 | Sönke Scherzer; Jennifer Böhm; Elzbieta Krol; Lana Shabala; Ines Kreuzer; Christina Larisch; Felix Bemm; Khaled A. S ..., Proceedings of the National Academy of Sciences current issue, 2015

The Darwin plant Dionaea muscipula is able to grow on mineral-poor soil, because it gains essential nutrients from captured animal prey. Given that no nutrients remain in the trap when it opens after the consumption of an animal meal, we here asked the question of how Dionaea sequesters ...

more

Water-soluble chlorophyll protein is involved in herbivore resistance activation during greening of Arabidopsis thaliana [Plant Biology]

09-Jun-2015 | Edouard Boex-Fontvieille; Sachin Rustgi; Diter von Wettstein; Steffen Reinbothe; Christiane Reinbothe, Proceedings of the National Academy of Sciences current issue, 2015

Water-soluble chlorophyll proteins (WSCPs) constitute a small family of unusual chlorophyll (Chl)-binding proteins that possess a Kunitz-type protease inhibitor domain. In Arabidopsis thaliana, a WSCP has been identified, named AtWSCP, that forms complexes with Chl and the Chl precursor ...

more

Page 1 From 163
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE