My watch list
my.chemeurope.com  
Login  

507 Newest Publications in proceedings of the national academy of sciences current issue

rss
matching the following criteria

Profile of Benjamin Cravatt [Profiles]

02-Feb-2016 | Jennifer Viegas, Proceedings of the National Academy of Sciences current issue, 2016

Bridging the fields of chemistry and biology, Benjamin Cravatt and his research group have developed and applied technologies to discover biochemical pathways in mammalian biology and disease. Cravatt, who was elected to the National Academy of Sciences in 2014 and is chair of the Department of ...

more

Protein carbamylation is a hallmark of aging [Chemistry]

02-Feb-2016 | Laëtitia Gorisse; Christine Pietrement; Vincent Vuiblet; Christian E. H. Schmelzer; Martin Köhler; Laurent Duca; Lau ..., Proceedings of the National Academy of Sciences current issue, 2016

Aging is a progressive process determined by genetic and acquired factors. Among the latter are the chemical reactions referred to as nonenzymatic posttranslational modifications (NEPTMs), such as glycoxidation, which are responsible for protein molecular aging. Carbamylation is a more recently ...

more

Onion-like glycodendrimersomes from sequence-defined Janus glycodendrimers and influence of architecture on reactivity to a lectin [Chemistry]

02-Feb-2016 | Qi Xiao; Shaodong Zhang; Zhichun Wang; Samuel E. Sherman; Ralph-Olivier Moussodia; Mihai Peterca; Adam Muncan; Dewig ..., Proceedings of the National Academy of Sciences current issue, 2016

A library of eight amphiphilic Janus glycodendrimers (GDs) with d-mannose (Man) headgroups, a known routing signal for lectin-mediated transport processes, was constructed via an iterative modular methodology. Sequence-defined variations of the Janus GD modulate the surface density and sequence ...

more

Close relation between quantum interference in molecular conductance and diradical existence [Chemistry]

26-Jan-2016 | Yuta Tsuji; Roald Hoffmann; Mikkel Strange; Gemma C. Solomon, Proceedings of the National Academy of Sciences current issue, 2016

An empirical observation of a relationship between a striking feature of electronic transmission through a π-system, destructive quantum interference (QI), on one hand, and the stability of diradicals on the other, leads to the proof of a general theorem that relates the two. Subject to a number ...

more

A single protein redox ruler [Chemistry]

12-Jan-2016 | Rajneesh K. Bains; Jeffrey J. Warren, Proceedings of the National Academy of Sciences current issue, 2016

Redox reactions are the heart of function in biological systems. Using a deceptively simple toolbox, consisting largely of first row transition metals and the 20 canonical amino acids, nature has evolved proteins that contain cofactors with reduction potentials (E°′) between +1 V and −1 V. ...

more

Profile of Tomas Lindahl, Paul Modrich, and Aziz Sancar, 2015 Nobel Laureates in Chemistry [Profiles]

12-Jan-2016 | James E. Cleaver, Proceedings of the National Academy of Sciences current issue, 2016

In 1994, Science magazine heralded “the DNA repair enzyme” as the molecule of the year, on the basis of several significant advances made in mismatch repair and nucleotide excision repair, both recognized by this year’s Chemistry Nobel awards, that heralds an even better year for the field. This ...

more

Design of a single protein that spans the entire 2-V range of physiological redox potentials [Chemistry]

12-Jan-2016 | Parisa Hosseinzadeh; Nicholas M. Marshall; Kelly N. Chacón; Yang Yu; Mark J. Nilges; Siu Yee New; Stoyan A. Tashkov; ..., Proceedings of the National Academy of Sciences current issue, 2016

The reduction potential (E°′) is a critical parameter in determining the efficiency of most biological and chemical reactions. Biology employs three classes of metalloproteins to cover the majority of the 2-V range of physiological E°′s. An ultimate test of our understanding of E°′ is to find out ...

more

Effects of DNA replication on mRNA noise [Chemistry]

29-Dec-2015 | Joseph R. Peterson; John A. Cole; Jingyi Fei; Taekjip Ha; Zaida A. Luthey-Schulten, Proceedings of the National Academy of Sciences current issue, 2015

There are several sources of fluctuations in gene expression. Here we study the effects of time-dependent DNA replication, itself a tightly controlled process, on noise in mRNA levels. Stochastic simulations of constitutive and regulated gene expression are used to analyze the time-averaged mean ...

more

Gut bacteria mediate aggregation in the German cockroach [Chemistry]

22-Dec-2015 | Ayako Wada-Katsumata; Ludek Zurek; Godfrey Nalyanya; Wendell L. Roelofs; Aijun Zhang; Coby Schal, Proceedings of the National Academy of Sciences current issue, 2015

Aggregation of the German cockroach, Blattella germanica, is regulated by fecal aggregation agents (pheromones), including volatile carboxylic acids (VCAs). We demonstrate that the gut microbial community contributes to production of these semiochemicals. Chemical analysis of the fecal extract of ...

more

Protein-like proton exchange in a synthetic host cavity [Chemistry]

15-Dec-2015 | William M. Hart-Cooper; Carmelo Sgarlata; Charles L. Perrin; F. Dean Toste; Robert G. Bergman; Kenneth N. Raymond, Proceedings of the National Academy of Sciences current issue, 2015

The mechanism of proton exchange in a metal–ligand enzyme active site mimic (compound 1) is described through amide hydrogen–deuterium exchange kinetics. The type and ratio of cationic guest to host in solution affect the rate of isotope exchange, suggesting that the rate of exchange is driven by ...

more

Page 1 From 51
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE