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304 Newest Publications in proceedings of the national academy of sciences current issue

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Induced plant defenses, host-pathogen interactions, and forest insect outbreaks [Ecology]

10-09-2013 | Bret D. Elderd; Brian J. Rehill; Kyle J. Haynes; Greg Dwyer, Proceedings of the National Academy of Sciences current issue, 2013

Cyclic outbreaks of defoliating insects devastate forests, but their causes are poorly understood. Outbreak cycles are often assumed to be driven by density-dependent mortality due to natural enemies, because pathogens and predators cause high mortality and because natural-enemy models reproduce ...

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Surge of neurophysiological coherence and connectivity in the dying brain [Neuroscience]

27-08-2013 | Jimo Borjigin; UnCheol Lee; Tiecheng Liu; Dinesh Pal; Sean Huff; Daniel Klarr; Jennifer Sloboda; Jason Hernandez; Mi ..., Proceedings of the National Academy of Sciences current issue, 2013

The brain is assumed to be hypoactive during cardiac arrest. However, the neurophysiological state of the brain immediately following cardiac arrest has not been systematically investigated. In this study, we performed continuous electroencephalography in rats undergoing experimental cardiac ...

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Climate, fishing, and fluctuations of sardine and anchovy in the California Current [Population Biology]

13-08-2013 | Martin Lindegren; David M. Checkley, Jr.; Tristan Rouyer; Alec D. MacCall; Nils Chr. Stenseth, Proceedings of the National Academy of Sciences current issue, 2013

Since the days of Elton, population cycles have challenged ecologists and resource managers. Although the underlying mechanisms remain debated, theory holds that both density-dependent and density-independent processes shape the dynamics. One striking example is the large-scale fluctuations of ...

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Hyperuniformity in amorphous silicon based on the measurement of the infinite-wavelength limit of the structure factor [Applied Physical Sciences]

13-08-2013 | Ruobing Xie; Gabrielle G. Long; Steven J. Weigand; Simon C. Moss; Tobi Carvalho; Sjoerd Roorda; Miroslav Hejna; Salv ..., Proceedings of the National Academy of Sciences current issue, 2013

We report the results of highly sensitive transmission X-ray scattering measurements performed at the Advanced Photon Source, Argonne National Laboratory, on nearly fully dense high-purity amorphous-silicon (a-Si) samples for the purpose of determining their degree of hyperuniformity. A perfectly ...

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Electronic states of the O2-tolerant [NiFe] hydrogenase proximal cluster [Biological Sciences]

09-07-2013 | Jean-Marie Mouesca; Patricia Amara; Juan C. Fontecilla-Camps, Proceedings of the National Academy of Sciences current issue, 2013

Recently, Pandelia et al. (1) used density functional theory (DFT) calculations to interpret their Mössbauer experiments on the superoxidized state of the O2-tolerant hydrogenase [4Fe3S] proximal cluster. Experimentally (table 2 in ref. 1), the subspectrum (S) exhibits the largest quadrupole ...

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Reply to Mouesca et al.: Electronic structure of the proximal [4Fe-3S] cluster of O2-tolerant [NiFe] hydrogenases [Biological Sciences]

09-07-2013 | Maria-Eirini Pandelia; Dmytro Bykov; Robert Izsak; Pascale Infossi; Marie-Thérèse Giudici-Orticoni; Eckhard Bill; Fr ..., Proceedings of the National Academy of Sciences current issue, 2013

Mouesca et al. (1) criticize our analysis (2) of the superoxidized proximal [4Fe-3S]5+ cluster in O2-tolerant hydrogenases (A) that was also studied in Volbeda et al. (3), albeit from a different organism. Both analyses were based on broken-symmetry (BS) density functional theory (DFT) ...

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Optimization criteria and biological process enrichment in homologous multiprotein modules [Systems Biology]

25-06-2013 | Luqman Hodgkinson; Richard M. Karp, Proceedings of the National Academy of Sciences current issue, 2013

Biological process enrichment is a widely used metric for evaluating the quality of multiprotein modules. In this study, we examine possible optimization criteria for detecting homologous multiprotein modules and quantify their effects on biological process enrichment. We find that modularity, ...

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Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction [Neuroscience]

25-06-2013 | Darrick T. Balu; Yan Li; Matthew D. Puhl; Michael A. Benneyworth; Alo C. Basu; Shunsuke Takagi; Vadim Y. Bolshakov; ..., Proceedings of the National Academy of Sciences current issue, 2013

Schizophrenia is characterized by reduced hippocampal volume, decreased dendritic spine density, altered neuroplasticity signaling pathways, and cognitive deficits associated with impaired hippocampal function. We sought to determine whether this diverse pathology could be linked to NMDA receptor ...

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Network topology for the formation of solvated electrons in binary CaO-Al2O3 composition glasses [Physics]

18-06-2013 | Jaakko Akola; Shinji Kohara; Koji Ohara; Akihiko Fujiwara; Yasuhiro Watanabe; Atsunobu Masuno; Takeshi Usuki; Takash ..., Proceedings of the National Academy of Sciences current issue, 2013

Glass formation in the CaO–Al2O3 system represents an important phenomenon because it does not contain typical network-forming cations. We have produced structural models of CaO–Al2O3 glasses using combined density functional theory–reverse Monte Carlo simulations and obtained structures that ...

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Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells [Systems Biology]

18-06-2013 | Martin Kampmann; Michael C. Bassik; Jonathan S. Weissman, Proceedings of the National Academy of Sciences current issue, 2013

A major challenge of the postgenomic era is to understand how human genes function together in normal and disease states. In microorganisms, high-density genetic interaction (GI) maps are a powerful tool to elucidate gene functions and pathways. We have developed an integrated methodology based ...

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