My watch list
my.chemeurope.com  
Login  

457 Newest Publications in proceedings of the national academy of sciences current issue

rss
matching the following criteria

Revealing bacterial targets of growth inhibitors encoded by bacteriophage T7 [Microbiology]

30-Dec-2014 | Shahar Molshanski-Mor; Ido Yosef; Ruth Kiro; Rotem Edgar; Miriam Manor; Michael Gershovits; Mia Laserson; Tal Pupko; ..., Proceedings of the National Academy of Sciences current issue, 2014

Today's arsenal of antibiotics is ineffective against some emerging strains of antibiotic-resistant pathogens. Novel inhibitors of bacterial growth therefore need to be found. The target of such bacterial-growth inhibitors must be identified, and one way to achieve this is by locating mutations ...

more

Silencing urease: A key evolutionary step that facilitated the adaptation of Yersinia pestis to the flea-borne transmission route [Microbiology]

30-Dec-2014 | Iman Chouikha; B. Joseph Hinnebusch, Proceedings of the National Academy of Sciences current issue, 2014

The arthropod-borne transmission route of Yersinia pestis, the bacterial agent of plague, is a recent evolutionary adaptation. Yersinia pseudotuberculosis, the closely related food-and water-borne enteric species from which Y. pestis diverged less than 6,400 y ago, exhibits significant oral ...

more

Wolbachia small noncoding RNAs and their role in cross-kingdom communications [Microbiology]

30-Dec-2014 | Jaime G. Mayoral; Mazhar Hussain; D. Albert Joubert; Iñaki Iturbe-Ormaetxe; Scott L. O’Neill; Sassan Asgari, Proceedings of the National Academy of Sciences current issue, 2014

In prokaryotes, small noncoding RNAs (snRNAs) of 50–500 nt are produced that are important in bacterial virulence and response to environmental stimuli. Here, we identified and characterized snRNAs from the endosymbiotic bacteria, Wolbachia, which are widespread in invertebrates and cause ...

more

pH modulates the activity and synergism of the airway surface liquid antimicrobials {beta}-defensin-3 and LL-37 [Microbiology]

30-Dec-2014 | Mahmoud H. Abou Alaiwa; Leah R. Reznikov; Nicholas D. Gansemer; Kelsey A. Sheets; Alexander R. Horswill; David A. St ..., Proceedings of the National Academy of Sciences current issue, 2014

The pulmonary airways are continuously exposed to bacteria. As a first line of defense against infection, the airway surface liquid (ASL) contains a complex mixture of antimicrobial factors that kill inhaled and aspirated bacteria. The composition of ASL is critical for antimicrobial ...

more

Subtle genetic modifications transformed an enteropathogen into a flea-borne pathogen [Microbiology]

30-Dec-2014 | Elisabeth Carniel, Proceedings of the National Academy of Sciences current issue, 2014

Yersinia pestis is the etiological agent of plague, one of the most devastating diseases in human history. Because of the identification of the plague bacillus, the understanding of its epidemiological cycle, and the advent of efficient antibiotic therapies, the death toll due to the plague has ...

more

Structure of the nonameric bacterial amyloid secretion channel [Microbiology]

16-Dec-2014 | Baohua Cao; Yan Zhao; Yongjun Kou; Dongchun Ni; Xuejun Cai Zhang; Yihua Huang, Proceedings of the National Academy of Sciences current issue, 2014

Various strains of bacteria are able to produce a unique class of functional amyloids termed curli, which are critical for biofilm formation, host cell adhesion, and colonization of inert surfaces. Curli are secreted via the type VIII bacterial secretion system, and they share biochemical and ...

more

Bioalcohol production by a new synthetic route in a hyperthermophilic archaeon [Microbiology]

09-Dec-2014 | Volker Müller, Proceedings of the National Academy of Sciences current issue, 2014

The still growing demand for bioethanol is currently met by two microbiological processes. The by far most important process is the use of first- (sugar) or second- (lignocellulosic biomass) generation raw materials and yeast as catalysts. Yeasts convert the sugars via glycolysis to pyruvate, ...

more

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex [Microbiology]

09-Dec-2014 | Devin Sok; Marit J. van Gils; Matthias Pauthner; Jean-Philippe Julien; Karen L. Saye-Francisco; Jessica Hsueh; Bryan ..., Proceedings of the National Academy of Sciences current issue, 2014

Broadly neutralizing antibodies (bnAbs) targeting the trimer apex of HIV envelope are favored candidates for vaccine design and immunotherapy because of their great neutralization breadth and potency. However, methods of isolating bnAbs against this site have been limited by the quaternary nature ...

more

The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity [Microbiology]

09-Dec-2014 | Lucy K. Shewell; Richard M. Harvey; Melanie A. Higgins; Christopher J. Day; Lauren E. Hartley-Tassell; Austen Y. Che ..., Proceedings of the National Academy of Sciences current issue, 2014

The cholesterol-dependent cytolysin (CDC) pneumolysin (Ply) is a key virulence factor of Streptococcus pneumoniae. Membrane cholesterol is required for the cytolytic activity of this toxin, but it is not clear whether cholesterol is the only cellular receptor. Analysis of Ply binding to a glycan ...

more

Single gene insertion drives bioalcohol production by a thermophilic archaeon [Microbiology]

09-Dec-2014 | Mirko Basen; Gerrit J. Schut; Diep M. Nguyen; Gina L. Lipscomb; Robert A. Benn; Cameron J. Prybol; Brian J. Vaccaro; ..., Proceedings of the National Academy of Sciences current issue, 2014

Bioethanol production is achieved by only two metabolic pathways and only at moderate temperatures. Herein a fundamentally different synthetic pathway for bioalcohol production at 70 °C was constructed by insertion of the gene for bacterial alcohol dehydrogenase (AdhA) into the archaeon ...

more

Page 1 From 46
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE