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505 Newest Publications in proceedings of the national academy of sciences current issue

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matching the following criteria

Metabolic and trophic interactions modulate methane production by Arctic peat microbiota in response to warming [Microbiology]

12-May-2015 | Alexander Tøsdal Tveit; Tim Urich; Peter Frenzel; Mette Marianne Svenning, Proceedings of the National Academy of Sciences current issue, 2015

Arctic permafrost soils store large amounts of soil organic carbon (SOC) that could be released into the atmosphere as methane (CH4) in a future warmer climate. How warming affects the complex microbial network decomposing SOC is not understood. We studied CH4 production of Arctic peat soil ...

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Membrane fusion during phage lysis [Microbiology]

28-Apr-2015 | Manoj Rajaure; Joel Berry; Rohit Kongari; Jesse Cahill; Ry Young, Proceedings of the National Academy of Sciences current issue, 2015

In general, phages cause lysis of the bacterial host to effect release of the progeny virions. Until recently, it was thought that degradation of the peptidoglycan (PG) was necessary and sufficient for osmotic bursting of the cell. Recently, we have shown that in Gram-negative hosts, phage lysis ...

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Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication [Microbiology]

28-Apr-2015 | Yury A. Bochkov; Kelly Watters; Shamaila Ashraf; Theodor F. Griggs; Mark K. Devries; Daniel J. Jackson; Ann C. Palme ..., Proceedings of the National Academy of Sciences current issue, 2015

Members of rhinovirus C (RV-C) species are more likely to cause wheezing illnesses and asthma exacerbations compared with other rhinoviruses. The cellular receptor for these viruses was heretofore unknown. We report here that expression of human cadherin-related family member 3 (CDHR3) enables ...

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Electrochemical detection of a single cytomegalovirus at an ultramicroelectrode and its antibody anchoring [Microbiology]

28-Apr-2015 | Jeffrey E. Dick; Adam T. Hilterbrand; Aliaksei Boika; Jason W. Upton; Allen J. Bard, Proceedings of the National Academy of Sciences current issue, 2015

We report observations of stochastic collisions of murine cytomegalovirus (MCMV) on ultramicroelectrodes (UMEs), extending the observation of discrete collision events on UMEs to biologically relevant analytes. Adsorption of an antibody specific for a virion surface glycoprotein allowed ...

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Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-fever Borrelia [Microbiology]

28-Apr-2015 | Alvaro Toledo; Javier D. Monzón; James L. Coleman; Juan C. Garcia-Monco; Jorge L. Benach, Proceedings of the National Academy of Sciences current issue, 2015

The Lyme disease (Borrelia burgdorferi) and relapsing-fever (Borrelia hispanica) agents have distinct infection courses, but both require cholesterol for growth. They acquire cholesterol from the environment and process it to form cholesterol glycolipids that are incorporated onto their ...

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Stochastic induction of persister cells by HipA through (p)ppGpp-mediated activation of mRNA endonucleases [Microbiology]

21-Apr-2015 | Elsa Germain; Mohammad Roghanian; Kenn Gerdes; Etienne Maisonneuve, Proceedings of the National Academy of Sciences current issue, 2015

The model organism Escherichia coli codes for at least 11 type II toxin–antitoxin (TA) modules, all implicated in bacterial persistence (multidrug tolerance). Ten of these encode messenger RNA endonucleases (mRNases) inhibiting translation by catalytic degradation of mRNA, and the 11th module, ...

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Rgg protein structure-function and inhibition by cyclic peptide compounds [Microbiology]

21-Apr-2015 | Vijay Parashar; Chaitanya Aggarwal; Michael J. Federle; Matthew B. Neiditch, Proceedings of the National Academy of Sciences current issue, 2015

Peptide pheromone cell–cell signaling (quorum sensing) regulates the expression of diverse developmental phenotypes (including virulence) in Firmicutes, which includes common human pathogens, e.g., Streptococcus pyogenes and Streptococcus pneumoniae. Cytoplasmic transcription factors known as ...

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Structural basis for the geometry-driven localization of a small protein [Microbiology]

14-Apr-2015 | Richard L. Gill Jr.; Jean-Philippe Castaing; Jen Hsin; Irene S. Tan; Xingsheng Wang; Kerwyn Casey Huang; Fang Tian; ..., Proceedings of the National Academy of Sciences current issue, 2015

In bacteria, certain shape-sensing proteins localize to differently curved membranes. During sporulation in Bacillus subtilis, the only convex (positively curved) surface in the cell is the forespore, an approximately spherical internal organelle. Previously, we demonstrated that SpoVM localizes ...

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The circadian oscillator in Synechococcus elongatus controls metabolite partitioning during diurnal growth [Microbiology]

14-Apr-2015 | Spencer Diamond; Darae Jun; Benjamin E. Rubin; Susan S. Golden, Proceedings of the National Academy of Sciences current issue, 2015

Synechococcus elongatus PCC 7942 is a genetically tractable model cyanobacterium that has been engineered to produce industrially relevant biomolecules and is the best-studied model for a prokaryotic circadian clock. However, the organism is commonly grown in continuous light in the laboratory, ...

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Loose coupling in the bacterial flagellar motor [Microbiology]

14-Apr-2015 | Ryan Boschert; Frederick R. Adler; David F. Blair, Proceedings of the National Academy of Sciences current issue, 2015

Physiological properties of the flagellar rotary motor have been taken to indicate a tightly coupled mechanism in which each revolution is driven by a fixed number of energizing ions. Measurements that would directly test the tight-coupling hypothesis have not been made. Energizing ions flow ...

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