My watch list
my.chemeurope.com  
Login  

945 Newest Publications in proceedings of the national academy of sciences current issue

rss
matching the following criteria

Spatial embedding of structural similarity in the cerebral cortex [Neuroscience]

18-11-2014 | H. Francis Song; Henry Kennedy; Xiao-Jing Wang, Proceedings of the National Academy of Sciences current issue, 2014

Recent anatomical tracing studies have yielded substantial amounts of data on the areal connectivity underlying distributed processing in cortex, yet the fundamental principles that govern the large-scale organization of cortex remain unknown. Here we show that functional similarity between areas ...

more

Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice [Neuroscience]

18-11-2014 | Hai-Ying Zhang; Ming Gao; Qing-Rong Liu; Guo-Hua Bi; Xia Li; Hong-Ju Yang; Eliot L. Gardner; Jie Wu; Zheng-Xiong Xi, Proceedings of the National Academy of Sciences current issue, 2014

Cannabinoid CB2 receptors (CB2Rs) have been recently reported to modulate brain dopamine (DA)-related behaviors; however, the cellular mechanisms underlying these actions are unclear. Here we report that CB2Rs are expressed in ventral tegmental area (VTA) DA neurons and functionally modulate DA ...

more

Mosquito odorant receptor for DEET and methyl jasmonate [Neuroscience]

18-11-2014 | Pingxi Xu; Young-Moo Choo; Alyssa De La Rosa; Walter S. Leal, Proceedings of the National Academy of Sciences current issue, 2014

Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other vector-borne diseases. DEET (N,N-diethyl-3-methylbenzamide) is a 6-decade-old synthetic repellent, which is still considered the gold standard of ...

more

Anatomical accuracy of brain connections derived from diffusion MRI tractography is inherently limited [Neuroscience]

18-11-2014 | Cibu Thomas; Frank Q. Ye; M. Okan Irfanoglu; Pooja Modi; Kadharbatcha S. Saleem; David A. Leopold; Carlo Pierpaoli, Proceedings of the National Academy of Sciences current issue, 2014

Tractography based on diffusion-weighted MRI (DWI) is widely used for mapping the structural connections of the human brain. Its accuracy is known to be limited by technical factors affecting in vivo data acquisition, such as noise, artifacts, and data undersampling resulting from scan time ...

more

Asymmetrical integration of sensory information during mating decisions in grasshoppers [Neuroscience]

18-11-2014 | Jan Clemens; Stefanie Krämer; Bernhard Ronacher, Proceedings of the National Academy of Sciences current issue, 2014

Decision-making processes, like all traits of an organism, are shaped by evolution; they thus carry a signature of the selection pressures associated with choice behaviors. The way sexual communication signals are integrated during courtship likely reflects the costs and benefits associated with ...

more

SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination [Neuroscience]

18-11-2014 | Hong-Bin Luo; Yi-Yuan Xia; Xi-Ji Shu; Zan-Chao Liu; Ye Feng; Xing-Hua Liu; Guang Yu; Gang Yin; Yan-Si Xiong; Kuan Ze ..., Proceedings of the National Academy of Sciences current issue, 2014

Intracellular accumulation of the abnormally modified tau is hallmark pathology of Alzheimer’s disease (AD), but the mechanism leading to tau aggregation is not fully characterized. Here, we studied the effects of tau SUMOylation on its phosphorylation, ubiquitination, and degradation. We show ...

more

RHGF-1/PDZ-RhoGEF and retrograde DLK-1 signaling drive neuronal remodeling on microtubule disassembly [Neuroscience]

18-11-2014 | Chun-Hao Chen; Albert Lee; Chien-Po Liao; Ya-Wen Liu; Chun-Liang Pan, Proceedings of the National Academy of Sciences current issue, 2014

Neurons remodel their connectivity in response to various insults, including microtubule disruption. How neurons sense microtubule disassembly and mount remodeling responses by altering genetic programs in the soma are not well defined. Here we show that in response to microtubule disassembly, ...

more

CDK5 activator protein p25 preferentially binds and activates GSK3{beta} [Neuroscience]

11-11-2014 | Hei-Man Chow; Dong Guo; Jie-Chao Zhou; Guan-Yun Zhang; Hui-Fang Li; Karl Herrup; Jie Zhang, Proceedings of the National Academy of Sciences current issue, 2014

Glycogen synthase kinase 3β (GSK3β) and cyclin-dependent kinase 5 (CDK5) are tau kinases and have been proposed to contribute to the pathogenesis of Alzheimer’s disease. The 3D structures of these kinases are remarkably similar, which led us to hypothesize that both might be capable of binding ...

more

New approach to capture and characterize synaptic proteome [Neuroscience]

11-11-2014 | Xin-An Liu; Beena Kadakkuzha; Bruce Pascal; Caitlin Steckler; Komolitdin Akhmedov; Long Yan; Michael Chalmers; Sathy ..., Proceedings of the National Academy of Sciences current issue, 2014

Little is known regarding the identity of the population of proteins that are transported and localized to synapses. Here we describe a new approach that involves the isolation and systematic proteomic characterization of molecular motor kinesins to identify the populations of proteins ...

more

Activity-dependent FUS dysregulation disrupts synaptic homeostasis [Neuroscience]

04-11-2014 | Chantelle F. Sephton; Amy A. Tang; Ashwinikumar Kulkarni; James West; Mieu Brooks; Jeremy J. Stubblefield; Yun Liu; ..., Proceedings of the National Academy of Sciences current issue, 2014

The RNA-binding protein fused-in-sarcoma (FUS) has been associated with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), two neurodegenerative disorders that share similar clinical and pathological features. Both missense mutations and overexpression of wild-type ...

more

Page 1 From 95
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE